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AT2G15090.1
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
plasma membrane 0.959
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : 3-ketoacyl-CoA synthase 8
Curator
Summary (TAIR10)
Encodes KCS8, a member of the 3-ketoacyl-CoA synthase family involved in the biosynthesis of VLCFA (very long chain fatty acids).
Computational
Description (TAIR10)
3-ketoacyl-CoA synthase 8 (KCS8); FUNCTIONS IN: transferase activity, transferring acyl groups other than amino-acyl groups, catalytic activity, acyltransferase activity; INVOLVED IN: fatty acid elongation, very long-chain fatty acid metabolic process, response to osmotic stress; LOCATED IN: endoplasmic reticulum; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Thiolase-like (InterPro:IPR016039), Very-long-chain 3-ketoacyl-CoA synthase (InterPro:IPR012392), 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C-terminal (InterPro:IPR013747), FAE1/Type III polyketide synthase-like protein (InterPro:IPR013601), Thiolase-like, subgroup (InterPro:IPR016038); BEST Arabidopsis thaliana protein match is: 3-ketoacyl-CoA synthase 16 (TAIR:AT4G34250.1); Has 4430 Blast hits to 4415 proteins in 1092 species: Archae - 0; Bacteria - 1687; Metazoa - 0; Fungi - 24; Plants - 2579; Viruses - 0; Other Eukaryotes - 140 (source: NCBI BLink).
Protein Annotations
BioCyc:ARA:AT2G15090-MONOMEREC:2.3.1.199eggNOG:COG3424eggNOG:ENOG410JXF3
EMBL:AC005957EMBL:AK229027EMBL:BT023427EMBL:CP002685
EnsemblPlants:AT2G15090EnsemblPlants:AT2G15090.1entrez:815998Gene3D:3.40.47.10
GeneID:815998Genevisible:Q4V3C9GO:GO:0005783GO:GO:0005789
GO:GO:0006633GO:GO:0016021GO:GO:0016747Gramene:AT2G15090.1
gramene_pathway:2.3.1.-gramene_pathway:PWY-5080hmmpanther:PTHR31561HOGENOM:HOG000238893
InParanoid:Q4V3C9InterPro:IPR012392InterPro:IPR013601InterPro:IPR013747
InterPro:IPR016039KEGG:00061+2.3.1.180KEGG:00062+2.3.1.199KEGG:ath:AT2G15090
KO:K15397OMA:MGHARRAPANTHER:PTHR31561PaxDb:Q4V3C9
Pfam:PF08392Pfam:PF08541Pfam:Q4V3C9PhylomeDB:Q4V3C9
PIR:H84524PIRSF:PIRSF036417PRIDE:Q4V3C9PRO:PR:Q4V3C9
ProteinModelPortal:Q4V3C9Proteomes:UP000006548RefSeq:NP_179113.2SMR:Q4V3C9
STRING:3702.AT2G15090.1SUPFAM:SSF53901TAIR:AT2G15090tair10-symbols:KCS8
TMHMM:TMhelixUniGene:At.13393UniGene:At.67117UniPathway:UPA00094
UniProt:Q4V3C9
Coordinates (TAIR10) chr2:+:6542336..6543781
Molecular Weight (calculated) 54194.20 Da
IEP (calculated) 9.36
GRAVY (calculated) -0.09
Length 481 amino acids
Sequence (TAIR10)
(BLAST)
001: MKNLKMVFFK ILFISLMAGL AMKGSKINVE DLQKFSLHHT QNNLQTISLL LFLVVFVWIL YMLTRPKPVY LVDFSCYLPP SHLKVSIQTL MGHARRAREA
101: GMCWKNKESD HLVDFQEKIL ERSGLGQETY IPEGLQCFPL QQGMGASRKE TEEVIFGALD NLFRNTGVKP DDIGILVVNS STFNPTPSLA SMIVNKYKLR
201: DNIKSLNLGG MGCSAGVIAV DVAKGLLQVH RNTYAIVVST ENITQNLYLG KNKSMLVTNC LFRVGGAAVL LSNRSRDRNR AKYELVHTVR IHTGSDDRSF
301: ECATQEEDED GIIGVTLTKN LPMVAARTLK INIATLGPLV LPLKEKLAFF ITFVKKKYFK PELRNYTPDF KLAFEHFCIH AGGRALIDEL EKNLKLSPLH
401: VEASRMTLHR FGNTSSSSIW YELAYTEAKG RMKEGDRIWQ IALGSGFKCN SSVWVALRDV KPSANSPWED CMDRYPVEID I
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)