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AT2G13560.1
Subcellular Consensus
(Prediction and Experimental)
min: heatmap :max

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SUBAcon:
mitochondrion 1.000
ASURE: mitochondrion
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
  • PMID:31975158 (2020): plastid
  • PMID:31911558 (2020): mitochondrion
  • PMID:31871212 (2020): mitochondrion
  • PMID:31818904 (2020): mitochondrion
  • PMID:31615849 (2019): plastid plastid thylakoid
  • PMID:31520498 (2020): mitochondrion
  • PMID:31023727 (2019): mitochondrion
  • PMID:30783145 (2019): extracellular region plant-type cell wall
  • PMID:28865150 (2017): extracellular region plant-type cell wall
  • PMID:27943495 (2017): mitochondrion
  • PMID:24727099 (2014): mitochondrion
  • PMID:23673981 (2013): plastid plastid stroma plastoglobules
  • PMID:23444301 (2013): mitochondrion
  • PMID:22968828 (2012): mitochondrion
  • PMID:21841088 (2011): mitochondrion
  • PMID:21472856 (2011): mitochondrion
  • PMID:21311031 (2011): mitochondrion
  • PMID:17137349 (2006): mitochondrion
  • PMID:15028209 (2004): plastid
  • PMID:14671022 (2004): mitochondrion
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : NAD-dependent malic enzyme 1
Curator
Summary (TAIR10)
Encodes an NAD-dependent malic enzyme (NAD-ME) that does not act on oxaloacetate, indicating that it belongs to EC 1.1.1.39. It is a member of the alpha family of NAD-MEs in plants. It appears to function as a homodimer or as a heterodimer with the beta-type NAD-ME2 (At4g00570). NAD-ME1 transcript and protein levels are higher during the night than during the day.
Computational
Description (TAIR10)
NAD-dependent malic enzyme 1 (NAD-ME1); FUNCTIONS IN: in 7 functions; INVOLVED IN: response to salt stress, malate metabolic process; LOCATED IN: mitochondrion, chloroplast; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Malic enzyme, NAD-binding (InterPro:IPR012302), Malic oxidoreductase (InterPro:IPR001891), Malic enzyme, conserved site (InterPro:IPR015884), Malic enzyme, N-terminal (InterPro:IPR012301), NAD(P)-binding domain (InterPro:IPR016040); BEST Arabidopsis thaliana protein match is: NAD-dependent malic enzyme 2 (TAIR:AT4G00570.1); Has 9465 Blast hits to 9448 proteins in 2440 species: Archae - 143; Bacteria - 6328; Metazoa - 607; Fungi - 221; Plants - 457; Viruses - 0; Other Eukaryotes - 1709 (source: NCBI BLink).
Protein Annotations
BioCyc:ARA:AT2G13560-MONOMERBioGrid:1203BRENDA:1.1.1.39EC:1.1.1.39
eggNOG:COG0281eggNOG:KOG1257EMBL:AC007063EMBL:AY091108
EMBL:BT000996EMBL:CP002685EnsemblPlants:AT2G13560EnsemblPlants:AT2G13560.1
entrez:815842Gene3D:3.40.50.10380Gene3D:3.40.50.720GeneID:815842
Genevisible:Q9SIU0GO:GO:0004471GO:GO:0005524GO:GO:0005739
GO:GO:0006108GO:GO:0008270GO:GO:0009507GO:GO:0009651
GO:GO:0042803GO:GO:0050897GO:GO:0051287Gramene:AT2G13560.1
hmmpanther:PTHR23406hmmpanther:PTHR23406:SF2HOGENOM:HOG000042486InParanoid:Q9SIU0
InterPro:IPR001891InterPro:IPR012301InterPro:IPR012302InterPro:IPR015884
InterPro:IPR016040KEGG:ath:AT2G13560KO:K00028ncoils:Coil
OMA:ECLAAYMPaxDb:Q9SIU0Pfam:PF00390Pfam:PF03949
Pfam:Q9SIU0PhylomeDB:Q9SIU0PIR:E84508PIRSF:PIRSF000106
PRIDE:Q9SIU0PRINTS:PR00072PRO:PR:Q9SIU0PROSITE:PS00331
ProteinModelPortal:Q9SIU0Proteomes:UP000006548RefSeq:NP_178980.1scanprosite:PS00331
SMART:SM00919SMART:SM01274SMR:Q9SIU0STRING:3702.AT2G13560.1
SUPFAM:SSF51735SUPFAM:SSF53223TAIR:AT2G13560tair10-symbols:NAD-ME1
UniGene:At.28033UniProt:Q9SIU0
Coordinates (TAIR10) chr2:+:5650089..5655103
Molecular Weight (calculated) 69659.80 Da
IEP (calculated) 5.10
GRAVY (calculated) -0.23
Length 623 amino acids
Sequence (TAIR10)
(BLAST)
001: MGIANKLRLS SSSLSRILHR RILYSSAVRS FTTSEGHRPT IVHKQGLDIL HDPWFNKGTA FTMTERNRLD LRGLLPPNVM DSEQQIFRFM TDLKRLEEQA
101: RDGPSDPNAL AKWRILNRLH DRNETMYYKV LINNIEEYAP IVYTPTVGLV CQNYSGLFRR PRGMYFSAED RGEMMSMVYN WPAEQVDMIV VTDGSRILGL
201: GDLGVHGIGI AVGKLDLYVA AAGINPQRVL PVMIDVGTNN EKLRNDPMYL GLQQRRLEDD DYIDVIDEFM EAVYTRWPHV IVQFEDFQSK WAFKLLQRYR
301: CTYRMFNDDV QGTAGVAIAG LLGAVRAQGR PMIDFPKMKI VVAGAGSAGI GVLNAARKTM ARMLGNTETA FDSAQSQFWV VDAQGLITEG RENIDPEAQP
401: FARKTKEMER QGLKEGATLV EVVREVKPDV LLGLSAVGGL FSKEVLEAMK GSTSTRPAIF AMSNPTKNAE CTPQDAFSIL GENMIFASGS PFKNVEFGNG
501: HVGHCNQGNN MYLFPGIGLG TLLSGAPIVS DGMLQAASEC LAAYMSEEEV LEGIIYPPIS RIRDITKRIA AAVIKEAIEE DLVEGYREMD AREIQKLDEE
601: GLMEYVENNM WNPEYPTLVY KDD
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)