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AT2G07690.1
Subcellular Consensus
(Prediction and Experimental)

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SUBAcon:
nucleus 1.000
ASURE: nucleus
What is SUBAcon?
What is ASURE?
SUBAcon computations
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
Description (TAIR10) protein_coding : Minichromosome maintenance (MCM2/3/5) family protein
Curator
Summary (TAIR10)
Member of the minichromosome maintenance complex, involved in DNA replication initiation. Abundant in proliferating and endocycling tissues. Localized in the nucleus during G1, S and G2 phases of the cell cycle, and are released into the cytoplasmic compartment during mitosis. Binds chromatin.
Computational
Description (TAIR10)
MINICHROMOSOME MAINTENANCE 5 (MCM5); FUNCTIONS IN: DNA-dependent ATPase activity, DNA binding, ATP binding; INVOLVED IN: cell proliferation, DNA-dependent DNA replication initiation, DNA unwinding involved in replication; LOCATED IN: nuclear chromatin, nucleus, cytoplasm; EXPRESSED IN: 20 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Nucleic acid-binding, OB-fold-like (InterPro:IPR016027), Nucleic acid-binding, OB-fold (InterPro:IPR012340), DNA-dependent ATPase MCM (InterPro:IPR001208), DNA-dependent ATPase MCM, conserved site (InterPro:IPR018525), MCM protein 5 (InterPro:IPR008048); BEST Arabidopsis thaliana protein match is: Minichromosome maintenance (MCM2/3/5) family protein (TAIR:AT2G16440.1); Has 3980 Blast hits to 3841 proteins in 547 species: Archae - 376; Bacteria - 145; Metazoa - 1209; Fungi - 933; Plants - 431; Viruses - 3; Other Eukaryotes - 883 (source: NCBI BLink).
Protein Annotations
BioGrid:804EC:3.6.4.12eggNOG:COG1241eggNOG:KOG0481EMBL:AC004483EMBL:BX820823EMBL:CP002685
EnsemblPlants:AT2G07690EnsemblPlants:AT2G07690.1entrez:815415ExpressionAtlas:O80786Gene3D:2.40.50.140Gene3D:3.40.50.300GeneID:815415
Genevisible:O80786GO:GO:0000347GO:GO:0003678GO:GO:0003682GO:GO:0003688GO:GO:0005524GO:GO:0005634
GO:GO:0005737GO:GO:0006268GO:GO:0006270GO:GO:0007049GO:GO:0042555hmmpanther:PTHR11630hmmpanther:PTHR11630:SF42
HOGENOM:HOG000224128InParanoid:O80786IntAct:O80786InterPro:IPR001208InterPro:IPR008048InterPro:IPR012340InterPro:IPR018525
InterPro:IPR027417InterPro:IPR027925InterPro:IPR031327MINT:MINT-6799380OMA:YPSQRDIPaxDb:O80786Pfam:O80786
Pfam:PF00493Pfam:PF14551Pfscan:PS50051PhylomeDB:O80786PIR:G84487PRIDE:O80786PRINTS:PR01657
PRINTS:PR01661PRO:PR:O80786PROSITE:PS00847PROSITE:PS50051ProteinModelPortal:O80786Proteomes:UP000006548Reactome:R-ATH-68867
Reactome:R-ATH-68949Reactome:R-ATH-68962Reactome:R-ATH-69052Reactome:R-ATH-69300RefSeq:NP_178812.1scanprosite:PS00847SMART:SM00350
SMR:O80786STRING:3702.AT2G07690.1SUPFAM:SSF50249SUPFAM:SSF52540TAIR:AT2G07690tair10-symbols:MCM5UniGene:At.40911
UniProt:O80786
Coordinates (TAIR10) chr2:-:3523379..3527388
Molecular Weight (calculated) 81019.10 Da
IEP (calculated) 7.50
GRAVY (calculated) -0.37
Length 727 amino acids
Sequence (TAIR10)
(BLAST)
001: MSGWDEGAVY YSDQPQFPEA GDAATISPHA VLTKFKEFIR NFEIEQNCFP YREALLDNPK RLVVHLEDLL SFDSDLPSLI RSAPADYLPV FEKAAGEVLT
101: GLKMREANEG GVMEEPLTRD VQILLTSRED PVSMRLLGAQ YISKLVKISG ISIAASRVKA KATYVFLVCK NCKKTREVPC RPGLGGAIVP RSCDNIPQPG
201: EEPCPLDPWM VVPDRSQYVD QQTLKLQENP EDVPTGELPR NMLLSVDRHL VQTIVPGTRL TVMGIYSIFQ ASSSSNSHKG AVAIRQPYIR VVGLEDTNEA
301: SSRGPANFTP DEEEEFKKFA DSQDVYKNIC TKIAPSIFGH EDVKRAAACL LFGGSRKSLP DGVKLRGDIN VLLLGDPSTA KSQFLKFVEK TAPIAVYTSG
401: KGSSAAGLTA SVIRDSSTRE FYLEGGAMVL ADGGVVCIDE FDKMRPEDRV AIHEAMEQQT ISIAKAGITT VLNSRTSVLA AANPPSGRYD DLKTAQDNID
501: LQTTILSRFD LIFIVKDIRK YSQDKEIASH IIRVHASANK FSDENTDSKE DNWLKRYIQY CRARCHPRLS KDAAENLQRK YVTIRMDMKR RAHETGEAAP
601: IPITVRQLEA IVRLSESLAK MRLSHEATPD DVDKAFKLFD TSTMDAARSG INQQINITGE MANEIKQAET QIKRRMGIGA RLSERRLIED LARMGMNDSM
701: VRRALLIMHQ RGEVEYQRER RSIVRKA
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)