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AT2G02560.1
Subcellular Consensus
(Prediction and Experimental)
min: heatmap :max

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SUBAcon:
nucleus 0.999
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
  • PMID:31818904 (2020): mitochondrion
  • PMID:31615849 (2019): plastid plastid thylakoid
  • PMID:31520498 (2020): mitochondrion
  • PMID:30961429 (2019): nucleus
  • PMID:28865150 (2017): extracellular region plant-type cell wall
  • PMID:25900983 (2015): Golgi
  • PMID:25900983 (2015): Golgi trans-Golgi network
  • PMID:25900983 (2015): Golgi trans-Golgi network multivesicular body
  • PMID:25900983 (2015): plant-type vacuole plant-type vacuole membrane
  • PMID:22550958 (2012): plastid
  • PMID:21433285 (2011): plasma membrane
  • PMID:21166475 (2011): cytosol
  • PMID:17644812 (2007): plasma membrane
SUBAcon links
AGI-AGI relationships
Coexpression PPI
Description (TAIR10) protein_coding : cullin-associated and neddylation dissociated
Curator
Summary (TAIR10)
Arabidopsis thaliana homolog of human CAND1 (cullin-associated and neddylation-dissociated). Putative similarity to TBP-interacting protein TIP120. Ubiquitously expressed in plant tissues throughout development. T-DNA insertion mutant plants were completely sterile and resistant to sirtinol and auxin, but not to gibberellins or brassinolide. Displayed developmental phenotypes similar to those of axr1, namely, short petioles, downwardly curling leaves, shorter inflorescence. Required for SCF function and appears to modulate SCF complex cycling. Physically interacts with CUL1.
Computational
Description (TAIR10)
cullin-associated and neddylation dissociated (CAND1); FUNCTIONS IN: binding; INVOLVED IN: xylem and phloem pattern formation, response to auxin stimulus, vegetative to reproductive phase transition of meristem; LOCATED IN: cell wall, plasma membrane; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Armadillo-like helical (InterPro:IPR011989), Armadillo-type fold (InterPro:IPR016024), TATA-binding protein interacting (TIP20) (InterPro:IPR013932); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).
Protein Annotations
BioGrid:188DIP:DIP-33719NeggNOG:ENOG410XPK4eggNOG:KOG1824
EMBL:AC004136EMBL:AY099857EMBL:BT010134EMBL:CP002685
EnsemblPlants:AT2G02560EnsemblPlants:AT2G02560.1entrez:814786Gene3D:1.25.10.10
GeneID:814786Genevisible:Q8L5Y6GO:GO:0005618GO:GO:0005634
GO:GO:0005829GO:GO:0005886GO:GO:0006351GO:GO:0006355
GO:GO:0009733GO:GO:0010051GO:GO:0010228GO:GO:0010265
GO:GO:0016567hmmpanther:PTHR12696HOGENOM:HOG000264713InParanoid:Q8L5Y6
IntAct:Q8L5Y6InterPro:IPR011989InterPro:IPR013932InterPro:IPR016024
KEGG:ath:AT2G02560KO:K17263OMA:CLGKLTVPaxDb:Q8L5Y6
Pfam:PF08623Pfam:PF13646Pfam:Q8L5Y6PhylomeDB:Q8L5Y6
PIR:T00607PRIDE:Q8L5Y6PRO:PR:Q8L5Y6ProteinModelPortal:Q8L5Y6
Proteomes:UP000006548RefSeq:NP_001030954.1RefSeq:NP_178360.2STRING:3702.AT2G02560.1
SUPFAM:SSF48371SwissPalm:Q8L5Y6TAIR:AT2G02560tair10-symbols:ATCAND1
tair10-symbols:CAND1tair10-symbols:ETA2tair10-symbols:HVEtair10-symbols:TIP120
UniGene:At.41482UniProt:Q8L5Y6
Coordinates (TAIR10) chr2:+:690345..697342
Molecular Weight (calculated) 134905.00 Da
IEP (calculated) 5.98
GRAVY (calculated) -0.00
Length 1219 amino acids
Sequence (TAIR10)
(BLAST)
0001: MANLQVSGIL EKFQMTGKDK DYRYMATSDL LNELNKDSFK IDLDLEVRLS SIILQQLDDV AGDVSGLAVK CLAPLVKKVG EERIVEMTNK LCDKLLHGKD
0101: QHRDTASIAL RTVVAQIAPT LAPSILVTLT PQMIGGISGQ GMSSGIKCEC LEIMCDVVQK YGSLMTDDHE KLLNTLLLQL GCNQATVRKK TVTCIASLAS
0201: SLSDDLLAKA TVEVVKNLSN RNAKSEITRT NIQMIGALCR AVGYRFGTHL GNTVPVLINY CTSASENDEE LREYSLQALE SFLLRCPRDI SPYCDEILNL
0301: TLEYISYDPN FTDNMEEDTD NETLEDEEDD ESANEYTDDE DASWKVRRAA AKCLAGLIVS RSEMLTKVYQ EACPKLIDRF KEREENVKMD VFNTFIDLLR
0401: QTGNVTKGQT DTDESSPKWL LKQEVSKIVK SINRQLREKS VKTKVGAFSV LRELVVVLPD CLADHIGSLV PGIERALNDK SSTSNLKIEA LVFTKLVLAS
0501: HAPPVFHPYI KALSSPVLAA VGERYYKVTA EALRVCGELV RVVRPSTAGM GFDFKPFVHP IYNAIMSRLT NQDQDQEVKE CAITCMGLVI STFGDQLRAE
0601: LPSCLPVLVD RMGNEITRLT AVKAFSVIAT SPLHINLSCV LDHLIAELTG FLRKANRVLR QATLITMNTL VTAYGDKIGS EAYEVILVEL SSLISVSDLH
0701: MTALALELCC TLMTGKSCSE NISLAVRNKV LPQALTLVKS PLLQGQALLD LQKFFEALVY HANTSFYTLL ESLLSCAKPS PQSGGVPKQA LYSIAQCVAV
0801: LCLAAGDKNC SSTVKMLMEI LKDDSGTNSA KQHLALLSLG EIGRRKDLSA HAGIETIVIE SFQSPFEEIK SAASYALGNI AVGNLSNYLP FILDQIDNQQ
0901: KKQYILLHSL KEVIVRQSVD KADFQNSSVE KILALLFNHC ESEEEGVRNV VAECLGKMAL IEPEKLVPAL QVRTTSPAAF TRATVVTAVK YSVVERPEKL
1001: DEIIFPQISS FLMLIKDGDR HVRRAAVSAL STFAHYKPNL IKGLLPELLP LLYDQTVIKK ELIRTVDLGP FKHVVDDGLE LRKAAFECVF TLVDSCLDQV
1101: NPSSFIVPFL KSGLEDHYDL KMLCHLILSL LADKCPSAVL AVLDSLVEPL HKTISFKPKQ DAVKQEHDRN EDMIRSALRA ISSLDRINGV DYSHKFKGLM
1201: GDMKRSVPLW EKFQTIRNE
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)