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AT2G01420.1
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
plasma membrane 1.000
ASURE: plasma membrane
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
Description (TAIR10) protein_coding : Auxin efflux carrier family protein
Curator
Summary (TAIR10)
Encodes a putative auxin efflux carrier that is localized in developing and mature root meristems. It is involved in the maintenance of embryonic auxin gradients. A role for AtPIN4 in generating a sink for auxin below the quiescent center of the root meristem that is essential for auxin distribution and patterning is proposed. In the root, PIN4 is detected around the quiescent center and cells surrounding it, and localizes basally in provascular cells. PIN4 expression is upregulated in brassinosteroid-insensitive mutant (PMID 16141452).
Computational
Description (TAIR10)
PIN-FORMED 4 (PIN4); FUNCTIONS IN: auxin:hydrogen symporter activity, transporter activity; INVOLVED IN: root development, pattern specification process, auxin polar transport; LOCATED IN: endomembrane system, integral to membrane; EXPRESSED IN: 27 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Auxin efflux carrier, subgroup (InterPro:IPR014024), Auxin efflux carrier (InterPro:IPR004776); BEST Arabidopsis thaliana protein match is: Auxin efflux carrier family protein (TAIR:AT1G70940.1); Has 1811 Blast hits to 1602 proteins in 498 species: Archae - 31; Bacteria - 1046; Metazoa - 12; Fungi - 10; Plants - 485; Viruses - 0; Other Eukaryotes - 227 (source: NCBI BLink).
Protein Annotations
eggNOG:ENOG410IJ59eggNOG:ENOG410Y9XEEMBL:AK221788EnsemblPlants:AT2G01420
EnsemblPlants:AT2G01420.1entrez:814670ExpressionAtlas:Q56X88GO:GO:0009734
GO:GO:0016021GO:GO:0055085hmmpanther:PTHR31752hmmpanther:PTHR31752:SF14
HOGENOM:HOG000238224InterPro:IPR004776InterPro:IPR014024PaxDb:Q56X88
Pfam:PF03547PRIDE:Q56X88STRING:3702.AT2G01420.2tair10-symbols:ATPIN4
tair10-symbols:PIN4TIGRfam:TIGR00946TIGRFAMs:TIGR00946TMHMM:TMhelix
UniProt:Q56X88
Coordinates (TAIR10) chr2:-:180478..183199
Molecular Weight (calculated) 66347.50 Da
IEP (calculated) 6.74
GRAVY (calculated) 0.21
Length 612 amino acids
Sequence (TAIR10)
(BLAST)
001: MITWHDLYTV LTAVVPLYVA MILAYGSVQW WKIFSPDQCS GINRFVAIFA VPLLSFHFIS TNDPYAMNFR FVAADTLQKI IMLVLLALWA NLTKNGSLEW
101: MITIFSLSTL PNTLVMGIPL LIAMYGTYAG SLMVQVVVLQ CIIWYTLLLF LFEYRGAKLL IMEQFPETGA SIVSFKVESD VVSLDGHDFL ETDAEIGNDG
201: KLHVTVRKSN ASRRSLMMTP RPSNLTGAEI YSLSSTPRGS NFNHSDFYSV MGFPGGRLSN FGPADLYSVQ SSRGPTPRPS NFEENNAVKY GFYNNTNSSV
301: PAAGSYPAPN PEFSTGTGVS TKPNKIPKEN QQQLQEKDSK ASHDAKELHM FVWSSSASPV SDVFGGGAGD NVATEQSEQG AKEIRMVVSD QPRKSGGDDI
401: GGLDSGEGER EIEKATAGLN KMGSNSTAEL EAAGGDGGGN NGTHMPPTSV MTRLILIMVW RKLIRNPNTY SSLIGLIWAL VAYRWHVAMP KILQQSISIL
501: SDAGLGMAMF SLGLFMALQP KIIACGNSVA TFAMAVRFIT GPAIMAVAGI AIGLHGDLLR IAIVQAALPQ GIVPFVFAKE YNVHPTILST GVIFGMLIAL
601: PITLVYYILL GL
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)