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AT1G80560.1
Subcellular Consensus
(Prediction and Experimental)
min: heatmap :max

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SUBAcon:
plastid 1.000
ASURE: plastid
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
  • PMID:31911558 (2020): mitochondrion
  • PMID:31520498 (2020): mitochondrion
  • PMID:31186290 (2019): cytosol None
  • PMID:30783145 (2019): extracellular region plant-type cell wall
  • PMID:30394608 (2019): plastid
  • PMID:28865150 (2017): extracellular region plant-type cell wall
  • PMID:26572690 (2016): extracellular region plant-type cell wall
  • PMID:24361574 (2014): plastid plastid stroma
  • PMID:24124904 (2013): plastid
  • PMID:23673981 (2013): plastid plastid stroma plastoglobules
  • PMID:22550958 (2012): plastid
  • PMID:21531424 (2011): plastid
  • PMID:20061580 (2010): plastid plastid stroma
  • PMID:18431481 (2008): plastid plastid stroma
  • PMID:16207701 (2006): plastid
  • PMID:12938931 (2003): plastid
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : isopropylmalate dehydrogenase 2
Curator
Summary (TAIR10)
The AtIMD2 is one out of 3 genes encoding the enzyme 3-isopropylmalate dehydrogenase involved in leucine biosynthesis in Arabidopsis. Its subcellular location has been targeted to plastids.
Computational
Description (TAIR10)
isopropylmalate dehydrogenase 2 (IMD2); FUNCTIONS IN: 3-isopropylmalate dehydrogenase activity; INVOLVED IN: leucine biosynthetic process, metabolic process; LOCATED IN: chloroplast, chloroplast stroma, plastid, chloroplast envelope; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Isopropylmalate dehydrogenase (InterPro:IPR004429), Isocitrate/isopropylmalate dehydrogenase (InterPro:IPR001804), Isocitrate/isopropylmalate dehydrogenase, conserved site (InterPro:IPR019818); BEST Arabidopsis thaliana protein match is: isopropylmalate dehydrogenase 3 (TAIR:AT1G31180.1); Has 15265 Blast hits to 15265 proteins in 2613 species: Archae - 395; Bacteria - 8292; Metazoa - 578; Fungi - 832; Plants - 243; Viruses - 0; Other Eukaryotes - 4925 (source: NCBI BLink).
Protein Annotations
BioGrid:29613BRENDA:1.1.1.85EC:1.1.1.85eggNOG:COG0473
eggNOG:KOG0786EMBL:AC018849EMBL:AY062441EMBL:AY114627
EMBL:CP002684EMBL:Y10216EnsemblPlants:AT1G80560EnsemblPlants:AT1G80560.1
entrez:844395Gene3D:3.40.718.10GeneID:844395Genevisible:P93832
GO:GO:0000287GO:GO:0003862GO:GO:0009098GO:GO:0009507
GO:GO:0009536GO:GO:0009570GO:GO:0009941GO:GO:0051287
Gramene:AT1G80560.1gramene_pathway:1.1.1.85gramene_pathway:LEUSYN-PWYHAMAP:MF_01033
hmmpanther:PTHR11835hmmpanther:PTHR11835:SF53HOGENOM:HOG000021112InParanoid:P93832
IntAct:P93832InterPro:IPR001804InterPro:IPR004429InterPro:IPR019818
InterPro:IPR024084iPTMnet:P93832KEGG:00290+1.1.1.85KEGG:00660+1.1.1.85
KEGG:ath:AT1G80560KO:K00052OMA:HCGPEVVPANTHER:PTHR11835
PaxDb:P93832PDB:3R8WPDBsum:3R8WPfam:P93832
Pfam:PF00180PhylomeDB:P93832PIR:F96837PRIDE:P93832
PRO:PR:P93832PROSITE:PS00470ProteinModelPortal:P93832Proteomes:UP000006548
RefSeq:NP_178171.1scanprosite:PS00470SMART:SM01329SMR:P93832
STRING:3702.AT1G80560.1SUPFAM:SSF53659TAIR:AT1G80560tair10-symbols:ATIMD2
tair10-symbols:IMD2TIGRfam:TIGR00169TIGRFAMs:TIGR00169UniGene:At.5371
UniPathway:UPA00048UniProt:P93832
Coordinates (TAIR10) chr1:+:30287833..30290126
Molecular Weight (calculated) 43373.30 Da
IEP (calculated) 5.85
GRAVY (calculated) -0.03
Length 405 amino acids
Sequence (TAIR10)
(BLAST)
001: MAAALQTNIR TVKVPATFRA VSKQSLAPFR VRCAVASPGK KRYTITLLPG DGIGPEVVSI AKNVLQQAGS LEGVEFNFRE MPIGGAALDL VGVPLPEETI
101: SAAKESDAVL LGAIGGYKWD NNEKHLRPEK GLLQIRAALK VFANLRPATV LPQLVDASTL KREVAEGVDL MVVRELTGGI YFGEPRGIKT NENGEEVGFN
201: TEVYAAHEID RIARVAFETA RKRRGKLCSV DKANVLEASI LWRKRVTALA SEYPDVELSH MYVDNAAMQL VRDPKQFDTI VTNNIFGDIL SDEASMITGS
301: IGMLPSASLS DSGPGLFEPI HGSAPDIAGQ DKANPLATIL SAAMLLKYGL GEEKAAKRIE DAVLVALNNG FRTGDIYSAG TKLVGCKEMG EEVLKSVDSQ
401: VPASV
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)