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AT1G78680.1
Subcellular Consensus
(Prediction and Experimental)

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SUBAcon:
vacuole 1.000
ASURE: vacuole
What is SUBAcon?
What is ASURE?
SUBAcon computations
Predictors External Curations
AmiGO : vacuole 15961386
SwissProt : extracellular 16381842
TAIR : vacuole 15539469
TAIR : vacuole 15961386
Experimental Localisations and PPI
FP MS/MS PPI
  • PMID:28155257 (2017): extracellular region plant-type cell wall
  • PMID:26572690 (2016): extracellular region plant-type cell wall
  • PMID:15539469 (2004): plant-type vacuole
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : gamma-glutamyl hydrolase 2
Curator
Summary (TAIR10)
The Arabidopsis protein AtGGH2 is a gamma-glutamyl hydrolase acting specifically on monoglutamates. The enzyme is involved in the tetrahydrofolate metabolism and located to the vacuole.
Computational
Description (TAIR10)
gamma-glutamyl hydrolase 2 (GGH2); FUNCTIONS IN: omega peptidase activity; INVOLVED IN: tetrahydrofolylpolyglutamate metabolic process; LOCATED IN: vacuole; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Peptidase C26, gamma-glutamyl hydrolase (InterPro:IPR015527), Peptidase C26 (InterPro:IPR011697); BEST Arabidopsis thaliana protein match is: gamma-glutamyl hydrolase 1 (TAIR:AT1G78660.2); Has 406 Blast hits to 402 proteins in 115 species: Archae - 3; Bacteria - 51; Metazoa - 191; Fungi - 0; Plants - 77; Viruses - 0; Other Eukaryotes - 84 (source: NCBI BLink).
Protein Annotations
BioCyc:ARA:GQT-2768-MONOMERBioGrid:29423BRENDA:3.4.19.9EC:3.4.19.9eggNOG:ENOG410XQKIeggNOG:KOG1559EMBL:AC005679
EMBL:AF067141EMBL:AY070047EMBL:AY096428EMBL:CP002684EnsemblPlants:AT1G78680EnsemblPlants:AT1G78680.1entrez:844204
ExpressionAtlas:O65355Gene3D:3.40.50.880GeneID:844204Genevisible:O65355GO:GO:0005615GO:GO:0005618GO:GO:0005773
GO:GO:0006508GO:GO:0006541GO:GO:0008242GO:GO:0034722GO:GO:0046900gramene_plant_reactome:1119484gramene_plant_reactome:6876394
hmmpanther:PTHR11315HOGENOM:HOG000006721InParanoid:O65355IntAct:O65355InterPro:IPR011697InterPro:IPR015527InterPro:IPR029062
KEGG:00790+3.4.19.9MEROPS:C26.003merops:C26.A03ncoils:CoilOMA:ACHQHRYPANTHER:PTHR11315PaxDb:O65355
Pfam:O65355Pfam:PF07722Pfscan:PS51275PhylomeDB:O65355PIR:F96815PIR:T52030PRIDE:O65355
PRO:PR:O65355PROSITE:PS51275ProteinModelPortal:O65355Proteomes:UP000006548RefSeq:NP_565186.2SMR:O65355STRING:3702.AT1G78680.1
SUPFAM:SSF52317TAIR:AT1G78680tair10-symbols:ATGGH2tair10-symbols:GGH2UniGene:At.10894UniProt:O65355
Coordinates (TAIR10) chr1:+:29593933..29596037
Molecular Weight (calculated) 38644.40 Da
IEP (calculated) 7.16
GRAVY (calculated) -0.06
Length 347 amino acids
Sequence (TAIR10)
(BLAST)
001: MWSYVWLPLV ALSLFKDSII MAKAATILLP SQTGFDISRS PVCSAPDPNL NYRPVIGILS HPGDGASGRL SNATDASSIA ASYVKLAESG GARVIPLIFN
101: EPEEILFQKL ELVNGVILTG GWAKEGLYFE IVKKIFNKVL ERNDAGEHFP IYAICLGFEL LTMIISQNRD IFEKMDARNS ASSLQFVENV NIQGTIFQRF
201: PPELLKKLGT DCLVMQNHRF GISPQSFEGN IALSNFFKIV TTCVDDNGKV YVSTVQSTKY PVTGFQWHPE KNAFEWGSSK IPHSEDAIQV TQHAANHLVS
301: EARKSLNRPE SKKVLSNLIY NYKPTYCGYA GIGYDEVYIF TQQRSLL
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)