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AT1G73590.1
Subcellular Consensus
(Prediction and Experimental)

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SUBAcon:
plasma membrane 1.000
ASURE: plasma membrane
What is SUBAcon?
What is ASURE?
SUBAcon computations
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
Description (TAIR10) protein_coding : Auxin efflux carrier family protein
Curator
Summary (TAIR10)
Encodes an auxin efflux carrier involved in shoot and root development. It is involved in the maintenance of embryonic auxin gradients. Loss of function severely affects organ initiation, pin1 mutants are characterised by an inflorescence meristem that does not initiate any flowers, resulting in the formation of a naked inflorescence stem. PIN1 is involved in the determination of leaf shape by actively promoting development of leaf margin serrations. In roots, the protein mainly resides at the basal end of the vascular cells, but weak signals can be detected in the epidermis and the cortex. Expression levels and polarity of this auxin efflux carrier change during primordium development suggesting that cycles of auxin build-up and depletion accompany, and may direct, different stages of primordium development. PIN1 action on plant development does not strictly require function of PGP1 and PGP19 proteins.
Computational
Description (TAIR10)
PIN-FORMED 1 (PIN1); FUNCTIONS IN: transporter activity; INVOLVED IN: in 14 processes; LOCATED IN: apical part of cell, plasma membrane, membrane, basal plasma membrane, cytoplasm; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Auxin efflux carrier, subgroup (InterPro:IPR014024), Auxin efflux carrier (InterPro:IPR004776); BEST Arabidopsis thaliana protein match is: Auxin efflux carrier family protein (TAIR:AT1G70940.1); Has 5945 Blast hits to 4479 proteins in 806 species: Archae - 51; Bacteria - 3010; Metazoa - 784; Fungi - 134; Plants - 814; Viruses - 35; Other Eukaryotes - 1117 (source: NCBI BLink).
Protein Annotations
BioGrid:28912DIP:DIP-40041NeggNOG:ENOG410IJ59eggNOG:ENOG410Y9XEEMBL:AC079676EMBL:AF089084EMBL:AF089085
EMBL:AF372950EMBL:AY093960EMBL:CP002684EnsemblPlants:AT1G73590EnsemblPlants:AT1G73590.1entrez:843693GeneID:843693
Genevisible:Q9C6B8GO:GO:0005215GO:GO:0005737GO:GO:0005783GO:GO:0005886GO:GO:0009505GO:GO:0009506
GO:GO:0009630GO:GO:0009640GO:GO:0009734GO:GO:0009793GO:GO:0009908GO:GO:0009925GO:GO:0009926
GO:GO:0010051GO:GO:0010229GO:GO:0010252GO:GO:0010315GO:GO:0010329GO:GO:0010338GO:GO:0010358
GO:GO:0016021GO:GO:0045177GO:GO:0048364GO:GO:0048367GO:GO:0048825GO:GO:0048826Gramene:AT1G73590.1
hmmpanther:PTHR31752hmmpanther:PTHR31752:SF14HOGENOM:HOG000238224InParanoid:Q9C6B8IntAct:Q9C6B8InterPro:IPR004776InterPro:IPR014024
iPTMnet:Q9C6B8KEGG:ath:AT1G73590KO:K13947OMA:YEEDKAGPaxDb:Q9C6B8Pfam:PF03547Pfam:Q9C6B8
PhylomeDB:Q9C6B8PIR:G96762PRIDE:Q9C6B8PRO:PR:Q9C6B8ProteinModelPortal:Q9C6B8Proteomes:UP000006548RefSeq:NP_177500.1
STRING:3702.AT1G73590.1TAIR:AT1G73590tair10-symbols:ATPIN1tair10-symbols:PIN1TCDB:2.A.69.1.1TIGRfam:TIGR00946TIGRFAMs:TIGR00946
TMHMM:TMhelixUniGene:At.10969UniProt:Q9C6B8
Coordinates (TAIR10) chr1:+:27659772..27662876
Molecular Weight (calculated) 67023.00 Da
IEP (calculated) 9.34
GRAVY (calculated) 0.10
Length 622 amino acids
Sequence (TAIR10)
(BLAST)
001: MITAADFYHV MTAMVPLYVA MILAYGSVKW WKIFTPDQCS GINRFVALFA VPLLSFHFIA ANNPYAMNLR FLAADSLQKV IVLSLLFLWC KLSRNGSLDW
101: TITLFSLSTL PNTLVMGIPL LKGMYGNFSG DLMVQIVVLQ CIIWYTLMLF LFEYRGAKLL ISEQFPDTAG SIVSIHVDSD IMSLDGRQPL ETEAEIKEDG
201: KLHVTVRRSN ASRSDIYSRR SQGLSATPRP SNLTNAEIYS LQSSRNPTPR GSSFNHTDFY SMMASGGGRN SNFGPGEAVF GSKGPTPRPS NYEEDGGPAK
301: PTAAGTAAGA GRFHYQSGGS GGGGGAHYPA PNPGMFSPNT GGGGGTAAKG NAPVVGGKRQ DGNGRDLHMF VWSSSASPVS DVFGGGGGNH HADYSTATND
401: HQKDVKISVP QGNSNDNQYV EREEFSFGNK DDDSKVLATD GGNNISNKTT QAKVMPPTSV MTRLILIMVW RKLIRNPNSY SSLFGITWSL ISFKWNIEMP
501: ALIAKSISIL SDAGLGMAMF SLGLFMALNP RIIACGNRRA AFAAAMRFVV GPAVMLVASY AVGLRGVLLH VAIIQAALPQ GIVPFVFAKE YNVHPDILST
601: AVIFGMLIAL PITLLYYILL GL
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)