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AT1G71750.1
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
cytosol 0.524
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
  • PMID:28865150 (2017): extracellular region plant-type cell wall
  • PMID:26572690 (2016): extracellular region plant-type cell wall
  • PMID:21166475 (2011): cytosol
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : Hypoxanthine-guanine phosphoribosyltransferase
Curator
Summary (TAIR10)
Encodes a protein with hypoxanthine-guanine-phosphoribosyltransferase activity. Unlike some related enzymes, it does not appear to act on xanthine in vitro. The enzyme catalyzes reactions occurring in both directions, but appears to prefer acting on guanine, followed by hypoxanthine, in vitro. The enzyme is likely to function in purine salvage pathways and appears to be important for seed germination.
Computational
Description (TAIR10)
Hypoxanthine-guanine phosphoribosyltransferase (HGPT); FUNCTIONS IN: transferase activity, hypoxanthine phosphoribosyltransferase activity; INVOLVED IN: guanine metabolic process, nucleoside metabolic process, seed germination, hypoxanthine metabolic process; LOCATED IN: cytoplasm; EXPRESSED IN: 21 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Phosphoribosyltransferase (InterPro:IPR000836), Hypoxanthine phosphoribosyl transferase (InterPro:IPR005904); Has 5577 Blast hits to 5577 proteins in 2200 species: Archae - 45; Bacteria - 4400; Metazoa - 260; Fungi - 2; Plants - 42; Viruses - 0; Other Eukaryotes - 828 (source: NCBI BLink).
Protein Annotations
BioCyc:ARA:AT1G71750-MONOMERBioCyc:ARA:GQT-2577-MONOMERBioCyc:MetaCyc:AT1G71750-MONOMEREMBL:AY088917
EMBL:BT025544EMBL:CP002684EnsemblPlants:AT1G71750EnsemblPlants:AT1G71750.1
entrez:843505ExpressionAtlas:Q8L8L7Gene3D:3.40.50.2020GeneID:843505
GO:GO:0004422GO:GO:0005737GO:GO:0006166Gramene:AT1G71750.1
gramene_pathway:2.4.2.8gramene_pathway:PWY-6599hmmpanther:PTHR22573hmmpanther:PTHR22573:SF56
InterPro:IPR000836InterPro:IPR005904InterPro:IPR029057KEGG:00230+2.4.2.8
KEGG:00983+2.4.2.8Pfam:PF00156PhylomeDB:Q8L8L7Proteomes:UP000006548
Reactome:R-ATH-74217RefSeq:NP_177320.1SMR:Q8L8L7SUPFAM:SSF53271
TAIR:AT1G71750tair10-symbols:HGPTTIGRfam:TIGR01203TIGRFAMs:TIGR01203
UniGene:At.35167UniGene:At.52481unipathway:UPA00591UniProt:Q8L8L7
Coordinates (TAIR10) chr1:-:26987954..26989144
Molecular Weight (calculated) 20880.20 Da
IEP (calculated) 5.63
GRAVY (calculated) 0.06
Length 188 amino acids
Sequence (TAIR10)
(BLAST)
001: MALEKHIEKV LFSDEVIAHR VNQLGIDITS DFSGDSEETP IFVGVATGAC LFLADLVRRI DLPIAIDFIR AESYGSGTVS SGVPRVSFDL KLDITNKHVV
101: LVEDIVDTGN TLSCLIEHMK AKKASSVSVC TLLDKPSRRK VHYKLVGKGK FYSGFECPDE FVVGYGMDFA EQYRNLSYIG VLKPEYYM
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)