suba logo
AT1G70730.1
Subcellular Consensus
(Prediction and Experimental)
min: heatmap :max

.
SUBAcon:
cytosol 1.000
ASURE: cytosol
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
  • PMID:31520498 (2020): mitochondrion
  • PMID:31186290 (2019): cytosol None
  • PMID:30783145 (2019): extracellular region plant-type cell wall
  • PMID:30447334 (2019): plasma membrane
  • PMID:28865150 (2017): extracellular region plant-type cell wall
  • PMID:26781341 (2016): plasma membrane
  • PMID:26572690 (2016): extracellular region plant-type cell wall
  • PMID:24361574 (2014): plastid plastid stroma
  • PMID:24124904 (2013): plastid
  • PMID:22215637 (2012): plasma membrane
  • PMID:21988472 (2012): plant-type vacuole plant-type vacuole membrane
  • PMID:21433285 (2011): plasma membrane
  • PMID:21166475 (2011): cytosol
  • PMID:20061580 (2010): plastid plastid stroma
  • PMID:19334764 (2009): plasma membrane
  • PMID:17644812 (2007): plasma membrane
  • PMID:17317660 (2007): plasma membrane
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : Phosphoglucomutase/phosphomannomutase family protein
Curator
Summary (TAIR10)
Encodes a cytosolic phosphoglucomutase (PGM). Two Arabidopsis PGM proteins (AT1G70730/PGM2 and AT1G23190/PGM3) have high sequence similarities and redundant functions. Mature plants possessing a single cPGM allele had a major reduction in cPGM activity. Whereas pgm2 and pgm3 single mutants are undistinguishable from the wild type, loss of both PGM2 and PGM3 severely impairs male and female gametophyte development.
Computational
Description (TAIR10)
Phosphoglucomutase/phosphomannomutase family protein; FUNCTIONS IN: intramolecular transferase activity, phosphotransferases, magnesium ion binding, phosphoglucomutase activity; INVOLVED IN: response to cadmium ion, carbohydrate metabolic process; LOCATED IN: cytosol, nucleus, plasma membrane; EXPRESSED IN: 27 plant structures; EXPRESSED DURING: 16 growth stages; CONTAINS InterPro DOMAIN/s: Alpha-D-phosphohexomutase, conserved site (InterPro:IPR016066), Alpha-D-phosphohexomutase, C-terminal (InterPro:IPR005843), Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III (InterPro:IPR016055), Alpha-D-phosphohexomutase, alpha/beta/alpha domain III (InterPro:IPR005846), Alpha-D-phosphohexomutase, alpha/beta/alpha domain II (InterPro:IPR005845), Alpha-D-phosphohexomutase (InterPro:IPR005841), Alpha-D-phosphohexomutase, alpha/beta/alpha domain I (InterPro:IPR005844); BEST Arabidopsis thaliana protein match is: Phosphoglucomutase/phosphomannomutase family protein (TAIR:AT1G23190.1); Has 8013 Blast hits to 8000 proteins in 2264 species: Archae - 118; Bacteria - 6090; Metazoa - 518; Fungi - 215; Plants - 166; Viruses - 0; Other Eukaryotes - 906 (source: NCBI BLink).
Protein Annotations
BioCyc:ARA:AT1G70730-MONOMERBioCyc:ARA:GQT-1374-MONOMERBioCyc:ARA:GQT-1375-MONOMERBioGrid:28630
BRENDA:5.4.2.2EC:5.4.2.2eggNOG:COG0033eggNOG:KOG0625
EMBL:AC011663EMBL:AY090231EMBL:BT002627EMBL:CP002684
EnsemblPlants:AT1G70730EnsemblPlants:AT1G70730.1entrez:843410ExpressionAtlas:Q9SGC1
Gene3D:3.30.310.50Gene3D:3.40.120.10GeneID:843410Genevisible:Q9SGC1
GO:GO:0000287GO:GO:0004614GO:GO:0005737GO:GO:0006006
gramene_pathway:5.4.2.2gramene_pathway:PWY-5661gramene_pathway:PWY-621gramene_pathway:PWY-622
gramene_pathway:PWY-842gramene_pathway:PWYQT-4437gramene_pathway:PWYQT-4466gramene_pathway:SUCSYN-PWY
hmmpanther:PTHR22573hmmpanther:PTHR22573:SF47HOGENOM:HOG000009550InParanoid:Q9SGC1
InterPro:IPR005841InterPro:IPR005843InterPro:IPR005844InterPro:IPR005845
InterPro:IPR005846InterPro:IPR016055InterPro:IPR016066iPTMnet:Q9SGC1
KEGG:00520+5.4.2.10PaxDb:Q9SGC1Pfam:PF00408Pfam:PF02878
Pfam:PF02879Pfam:PF02880Pfam:Q9SGC1PhylomeDB:Q9SGC1
PIR:G96731PRIDE:Q9SGC1PRINTS:PR00509PRO:PR:Q9SGC1
PROSITE:PS00710ProteinModelPortal:Q9SGC1Proteomes:UP000006548Reactome:R-ATH-3322077
Reactome:R-ATH-70221Reactome:R-ATH-70370RefSeq:NP_177230.1scanprosite:PS00710
SMR:Q9SGC1STRING:3702.AT1G70730.3SUPFAM:SSF53738SUPFAM:SSF55957
TAIR:AT1G70730tair10-symbols:PGM2UniGene:At.35274UniProt:Q0WN31
UniProt:Q9SGC1
Coordinates (TAIR10) chr1:-:26669020..26672726
Molecular Weight (calculated) 63485.40 Da
IEP (calculated) 5.57
GRAVY (calculated) -0.19
Length 585 amino acids
Sequence (TAIR10)
(BLAST)
001: MVSFKVSLVS TSPIDGQKPG TSGLRKKVKV FKQPNYLENF VQATFNALTT EKVKGATLVV SGDGRYYSEQ AIQIIVKMAA ANGVRRVWVG QNSLLSTPAV
101: SAIIRERVGA DGSKATGAFI LTASHNPGGP TEDFGIKYNM ENGGPAPESI TDKIYENTKT IKEYPIAEDL PRVDISTIGI TSFEGPEGKF DVEVFDSADD
201: YVKLMKSIFD FESIKKLLSY PKFTFCYDAL HGVAGAYAHR IFVEELGAPE SSLLNCVPKE DFGGGHPDPN LTYAKELVAR MGLSKTDDAG GEPPEFGAAA
301: DGDADRNMIL GKRFFVTPSD SVAIIAANAV GAIPYFSSGL KGVARSMPTS AALDVVAKNL GLKFFEVPTG WKFFGNLMDA GMCSVCGEES FGTGSDHIRE
401: KDGIWAVLAW LSILAHKNKE TLDGNAKLVT VEDIVRQHWA TYGRHYYTRY DYENVDATAA KELMGLLVKL QSSLPEVNKI IKGIHPEVAN VASADEFEYK
501: DPVDGSVSKH QGIRYLFEDG SRLVFRLSGT GSEGATIRLY IEQYEKDASK IGRDSQDALG PLVDVALKLS KMQEFTGRSS PTVIT
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)