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AT1G69770.1
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
nucleus 1.000
ASURE: nucleus
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : chromomethylase 3
Curator
Summary (TAIR10)
Encodes a chromomethylase involved in methylating cytosine residues at non-CG sites. Involved in preferentially methylating transposon-related sequences, reducing their mobility. CMT3 interacts with an Arabidopsis homologue of HP1 (heterochromatin protein 1), which in turn interacts with methylated histones. Involved in gene silencing.
Computational
Description (TAIR10)
chromomethylase 3 (CMT3); FUNCTIONS IN: DNA (cytosine-5-)-methyltransferase activity; INVOLVED IN: in 6 processes; LOCATED IN: chromatin, nucleus; EXPRESSED IN: 21 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: DNA methylase, C-5 cytosine-specific (InterPro:IPR001525), Chromo domain-like (InterPro:IPR016197), Bromo adjacent homology (BAH) domain (InterPro:IPR001025), DNA methylase, C-5 cytosine-specific, active site (InterPro:IPR018117), Chromo domain (InterPro:IPR000953); BEST Arabidopsis thaliana protein match is: chromomethylase 2 (TAIR:AT4G19020.1); Has 4337 Blast hits to 3739 proteins in 974 species: Archae - 208; Bacteria - 2545; Metazoa - 230; Fungi - 161; Plants - 416; Viruses - 30; Other Eukaryotes - 747 (source: NCBI BLink).
Protein Annotations
BioCyc:ARA:AT1G69770-MONOMERBioGrid:28534BRENDA:2.1.1.37DIP:DIP-60719N
EC:2.1.1.37eggNOG:COG0270eggNOG:ENOG410IH5KEMBL:AC013289
EMBL:AF364174EMBL:AF383170EMBL:CP002684EnsemblPlants:AT1G69770
EnsemblPlants:AT1G69770.1entrez:843313Gene3D:3.40.50.150GeneID:843313
Genevisible:Q94F88GO:GO:0003677GO:GO:0003682GO:GO:0003886
GO:GO:0005634GO:GO:0006306GO:GO:0006342GO:GO:0006351
GO:GO:0010069GO:GO:0010425GO:GO:0045814GO:GO:0051567
GO:GO:0090116Gramene:AT1G69770.1hmmpanther:PTHR10629hmmpanther:PTHR10629:SF28
HOGENOM:HOG000082844InParanoid:Q94F88InterPro:IPR000953InterPro:IPR001025
InterPro:IPR001525InterPro:IPR016197InterPro:IPR018117InterPro:IPR023779
InterPro:IPR023780InterPro:IPR029063KEGG:ath:AT1G69770KO:K00558
OMA:HRPLELNPaxDb:Q94F88Pfam:PF00145Pfam:PF00385
Pfam:PF01426Pfam:Q94F88Pfscan:PS50013Pfscan:PS51038
Pfscan:PS51679PhylomeDB:Q94F88PIR:G96719PRIDE:Q94F88
PRINTS:PR00105PRO:PR:Q94F88PROSITE:PS00094PROSITE:PS00598
PROSITE:PS50013PROSITE:PS51038PROSITE:PS51679ProteinModelPortal:Q94F88
Proteomes:UP000006548REBASE:4853RefSeq:NP_177135.1scanprosite:PS00094
scanprosite:PS00598SMART:SM00298SMART:SM00439SMR:Q94F88
STRING:3702.AT1G69770.1SUPFAM:SSF53335SUPFAM:SSF54160TAIR:AT1G69770
tair10-symbols:CMT3TIGRfam:TIGR00675TIGRFAMs:TIGR00675UniGene:At.35376
UniProt:Q94F88
Coordinates (TAIR10) chr1:-:26248496..26253519
Molecular Weight (calculated) 94910.00 Da
IEP (calculated) 7.00
GRAVY (calculated) -0.46
Length 839 amino acids
Sequence (TAIR10)
(BLAST)
001: MAPKRKRPAT KDDTTKSIPK PKKRAPKRAK TVKEEPVTVV EEGEKHVARF LDEPIPESEA KSTWPDRYKP IEVQPPKASS RKKTKDDEKV EIIRARCHYR
101: RAIVDERQIY ELNDDAYVQS GEGKDPFICK IIEMFEGANG KLYFTARWFY RPSDTVMKEF EILIKKKRVF FSEIQDTNEL GLLEKKLNIL MIPLNENTKE
201: TIPATENCDF FCDMNYFLPY DTFEAIQQET MMAISESSTI SSDTDIREGA AAISEIGECS QETEGHKKAT LLDLYSGCGA MSTGLCMGAQ LSGLNLVTKW
301: AVDMNAHACK SLQHNHPETN VRNMTAEDFL FLLKEWEKLC IHFSLRNSPN SEEYANLHGL NNVEDNEDVS EESENEDDGE VFTVDKIVGI SFGVPKKLLK
401: RGLYLKVRWL NYDDSHDTWE PIEGLSNCRG KIEEFVKLGY KSGILPLPGG VDVVCGGPPC QGISGHNRFR NLLDPLEDQK NKQLLVYMNI VEYLKPKFVL
501: MENVVDMLKM AKGYLARFAV GRLLQMNYQV RNGMMAAGAY GLAQFRLRFF LWGALPSEII PQFPLPTHDL VHRGNIVKEF QGNIVAYDEG HTVKLADKLL
601: LKDVISDLPA VANSEKRDEI TYDKDPTTPF QKFIRLRKDE ASGSQSKSKS KKHVLYDHHP LNLNINDYER VCQVPKRKGA NFRDFPGVIV GPGNVVKLEE
701: GKERVKLESG KTLVPDYALT YVDGKSCKPF GRLWWDEIVP TVVTRAEPHN QVIIHPEQNR VLSIRENARL QGFPDDYKLF GPPKQKYIQV GNAVAVPVAK
801: ALGYALGTAF QGLAVGKDPL LTLPEGFAFM KPTLPSELA
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)