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AT1G69190.1
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
cytosol 1.000
ASURE: cytosol
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no coexpression data no PPI data
Description (TAIR10) protein_coding : Dihydropterin pyrophosphokinase / Dihydropteroate synthase
Curator
Summary (TAIR10)
encodes a bifunctional cytosolic hydroxymethyldihydropterin pyrophosphokinase/ dihydropteroate synthase (HPPK/DHPS)that is involved in tetrahydrofolate biosynthesis and is responsive to oxidative stress.
Computational
Description (TAIR10)
Dihydropterin pyrophosphokinase / Dihydropteroate synthase; CONTAINS InterPro DOMAIN/s: Dihydropteroate synthase-like (InterPro:IPR011005), 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK (InterPro:IPR000550), Dihydropteroate synthase (InterPro:IPR006390), Pterin-binding (InterPro:IPR000489); BEST Arabidopsis thaliana protein match is: Dihydropterin pyrophosphokinase / Dihydropteroate synthase (TAIR:AT4G30000.1); Has 15022 Blast hits to 14981 proteins in 2537 species: Archae - 158; Bacteria - 9759; Metazoa - 8; Fungi - 169; Plants - 69; Viruses - 0; Other Eukaryotes - 4859 (source: NCBI BLink).
Protein Annotations
BioCyc:ARA:AT1G69190-MONOMERBRENDA:2.5.1.15EC:2.5.1.15EC:2.7.6.3
eggNOG:COG0294eggNOG:COG0801eggNOG:KOG2544EMBL:AC008262
EMBL:AC018364EMBL:AJ866732EMBL:CP002684EnsemblPlants:AT1G69190
EnsemblPlants:AT1G69190.1entrez:843250Gene3D:3.20.20.20Gene3D:3.30.70.560
GeneID:843250Genevisible:Q1ENB6GO:GO:0003848GO:GO:0004156
GO:GO:0005524GO:GO:0005829GO:GO:0006979GO:GO:0016301
GO:GO:0046654GO:GO:0046656GO:GO:0046872Gramene:AT1G69190.1
gramene_pathway:2.5.1.15gramene_pathway:2.7.6.3gramene_pathway:PWY-3742gramene_plant_reactome:1119265
gramene_plant_reactome:6874043hmmpanther:PTHR20941hmmpanther:PTHR20941:SF1HOGENOM:HOG000217511
InterPro:IPR000489InterPro:IPR000550InterPro:IPR006390InterPro:IPR011005
KEGG:00790+2.5.1.15KEGG:00790+2.7.6.3KEGG:ath:AT1G69190KO:K13941
OMA:MELPKIRPaxDb:Q1ENB6Pfam:PF00809Pfam:PF01288
Pfam:Q1ENB6Pfscan:PS50972PhylomeDB:Q1ENB6PIR:H96715
PRO:PR:Q1ENB6PROSITE:PS00792PROSITE:PS00793PROSITE:PS00794
PROSITE:PS50972ProteinModelPortal:Q1ENB6Proteomes:UP000006548RefSeq:NP_564953.2
scanprosite:PS00792scanprosite:PS00793scanprosite:PS00794SMR:Q1ENB6
STRING:3702.AT1G69190.1SUPFAM:SSF51717SUPFAM:SSF55083TAIR:AT1G69190
TIGRfam:TIGR01496TIGRfam:TIGR01498TIGRFAMs:TIGR01496TIGRFAMs:TIGR01498
UniGene:At.70808UniPathway:UPA00077UniProt:Q1ENB6
Coordinates (TAIR10) chr1:-:26013131..26014709
Molecular Weight (calculated) 54113.60 Da
IEP (calculated) 6.08
GRAVY (calculated) -0.20
Length 484 amino acids
Sequence (TAIR10)
(BLAST)
001: MDFTSLETTT FEEVVIALGS NVGNRMNNFK EALRLMKDYG ISVTRHSCLY ETEPVHVTDQ PRFLNAAIRG VTKLKPHELL NVLKKIEKEM GREENGLRYG
101: PRPLDLDILF YGKHKIISDK LIIPHERIWE RPFVLAPLVD LLGTEDIDND KIVAYWHSLS MHSGGIFQAW ERLGGESLLG KDGIIQRVIP IGDHLWDFSK
201: KTYVMGILNL TPDSFSDGGK FQSVDTAVSR VRSMISEGVD IIDIGAQSTR PMASRISSQE EIDRLIPVLK VVRGMAEMKG KLISVDTFNS EVALEAIRNG
301: ADILNDVSGG SLDENMHKVV ADSDVPYMIM HMRGDPCTMQ NKENLEYNEI CKDVATELYE RVREAELSGI PAWRIMIDPG IGFSKGIDHN LDIVMELPKI
401: REEMAKKSIG LSHAPILIGP SRKRFLGDIC GRPEASERDA ATVACVTAGI LKGANIIRVH NVRDNVDAAR LCDAMMTKRF KNVD
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)