AT1G68890.1
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Subcellular Consensus
(Prediction and Experimental) min:  :max.
SUBAcon:plastid 1.000 What is SUBAcon? |
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| Experimental Localisations and PPI |
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SUBAcon links
AGI-AGI relationships |
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| Description (TAIR10) | protein_coding : magnesium ion binding;thiamin pyrophosphate binding;hydro-lyases;catalytics;2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthases | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Curator Summary (TAIR10) |
Homologous to the four eubacterial men genes involved in menanoquinone biosynthesis. Studies of mutants defective in this gene demonstrated its involvement in phylloquinone biosynthesis in Arabidopsis. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Computational Description (TAIR10) |
magnesium ion binding;thiamin pyrophosphate binding;hydro-lyases;catalytics;2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthases; FUNCTIONS IN: 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase activity, hydro-lyase activity, magnesium ion binding, thiamin pyrophosphate binding, catalytic activity; INVOLVED IN: phylloquinone biosynthetic process, photosystem I stabilization; LOCATED IN: chloroplast; EXPRESSED IN: shoot, leaf whorl; CONTAINS InterPro DOMAIN/s: Menaquinone biosynthesis protein MenD (InterPro:IPR004433), Alpha/beta hydrolase fold-1 (InterPro:IPR000073), Mandelate racemase/muconate lactonizing enzyme, C-terminal (InterPro:IPR013342), Thiamine pyrophosphate enzyme, C-terminal TPP-binding (InterPro:IPR011766), Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain (InterPro:IPR012001), O-succinylbenzoic acid (OSB) synthetase, gamma proteobacteria/archaea (InterPro:IPR010196), Mandelate racemase/muconate lactonizing enzyme, conserved site (InterPro:IPR018110); BEST Arabidopsis thaliana protein match is: isochorismate synthase 2 (TAIR:AT1G18870.2); Has 22452 Blast hits to 22188 proteins in 2448 species: Archae - 403; Bacteria - 16894; Metazoa - 237; Fungi - 200; Plants - 484; Viruses - 7; Other Eukaryotes - 4227 (source: NCBI BLink). | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Protein Annotations |
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| Coordinates (TAIR10) | chr1:+:25896988..25906553 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Molecular Weight (calculated) | 190193.00 Da | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| IEP (calculated) | 6.57 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| GRAVY (calculated) | -0.02 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Length | 1715 amino acids | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Sequence (TAIR10) (BLAST) |
0001: MRSSFLVSNP PFLPSLIPRY SSRKSIRRSR ERFSFPESLR VSLLHGIRRN IEVAQGVQFD GPIMDRDVNL DDDLVVQVCV TRTLPPALTL ELGLESLKEA 0101: IDELKTNPPK SSSGVLRFQV AVPPRAKALF WFCSQPTTSD VFPVFFLSKD TVEPSYKSLY VKEPHGVFGI GNAFAFVHSS SVDSNGHSMI KTFLSDESAM 0201: VTAYGFPDIE FNKYSTVNSK DGSSYFFVPQ IELDEHEEVS ILAVTLAWNE SLSYTVEQTI SSYEKSIFQV SSHFCPNVED HWFKHLKSSL AKLSVEEIHP 0301: LEMEHMGFFT FSGRDQADVK ELKSIQSSCQ FHCKLSPDVV FSNNMLNRET EVSNFLRDEA NINAVWASAI IEECTRLGLT YFCVAPGSRS SHLAIAAANH 0401: PLTTCLACFD ERSLAFHAIG YAKGSLKPAV IITSSGTAVS NLLPAVVEAS EDFLPLLLLT ADRPPELQGV GANQAINQIN HFGSFVRFFF NLPPPTDLIP 0501: VRMVLTTVDS ALHWATGSAC GPVHLNCPFR DPLDGSPTNW SSNCLNGLDM WMSNAEPFTK YFQVQSHKSD GVTTGQITEI LQVIKEAKKG LLLIGAIHTE 0601: DEIWASLLLA KELMWPVVAD VLSGVRLRKL FKPFVEKLTH VFVDHLDHAL FSDSVRNLIE FDVVIQVGSR ITSKRVSQML EKCFPFAYIL VDKHPCRHDP 0701: SHLVTHRVQS NIVQFANCVL KSRFPWRRSK LHGHLQALDG AIAREMSFQI SAESSLTEPY VAHMLSKALT SKSALFIGNS MPIRDVDMYG CSSENSSHVV 0801: DMMLSAELPC QWIQVTGNRG ASGIDGLLSS ATGFAVGCKK RVVCVVGDIS FLHDTNGLAI LKQRIARKPM TILVINNRGG GIFRLLPIAK KTEPSVLNQY 0901: FYTAHDISIE NLCLAHGVRY VHVGTKSELE DALFVPSVEE MDCIVEVESS INANAIVHST LERFARQAAE NSLGIVSASS FLHPMIKNVL LCQVSGIQYS 1001: QYRVKLCDRP TICSDEFSQF HREGFILSLT LEDGSIGYGE VAPLNSNVEN LMDVEGQLQL VLHLMNEAKF SYMLPLLNGS ISSWIWSELG ITASSIFPSV 1101: RCGLEMALLN AMAVRHDSSL LGILHYQKEE NGSAQPHSVQ ICALLDSEGT PLEVAYVARK LVQEGFSAIK LKVGRRVSSV QDALVMQEVR RAVGVQIELR 1201: ADANCRWTFE EAREFGLLVN SCNLKYIEEP VQNKDDLIRF HEETGLPVAL DETLDDFEEC PLRMLTKYTH PGIVAVVIKP SVVGGFENAA LIARWAQQHG 1301: KMAVISAAYE SGLGLSAYIL FASYLEMENV KASTEQKQGT PPSVAHGLGT YRWLSEDVMM NTLGIFRSPY SGFVEGFIAD ASRNLKDVKI NNDVIVRTSK 1401: GIPVRRYELR VDVDGFSHFI RVHDVGENAE GSVALFLHGF LGTGEEWIPI MTGISGSARC ISVDIPGHGR SRVQSHASET QTSPTFSMEM IAEALYKLIE 1501: QITPGKVTIV GYSMGARIAL YMALRFSNKI EGAVVVSGSP GLKDPVARKI RSATDDSKAR MMVDNGLYIF IENWYNGGLW KSLRNHPHFS KIAASRLLHG 1601: DVPSVAKLLS DLSSGRQPSL WEELEDCDTN ISLVFGEKDV KYKQIATRMY REMSKSKKSV NNIIEIVEIP EAGHAVHLES PLRVILALRK FLTRVHNSST 1701: ETELSQKLLL ALKEM |
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| See Also |
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Citation
If you find this resource useful please cite one of the following publications:
Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)
Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)