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AT1G68890.1
Subcellular Consensus
(Prediction and Experimental)

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SUBAcon:
plastid 1.000
What is SUBAcon?
What is ASURE?
SUBAcon computations
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : magnesium ion binding;thiamin pyrophosphate binding;hydro-lyases;catalytics;2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthases
Curator
Summary (TAIR10)
Homologous to the four eubacterial men genes involved in menanoquinone biosynthesis. Studies of mutants defective in this gene demonstrated its involvement in phylloquinone biosynthesis in Arabidopsis.
Computational
Description (TAIR10)
magnesium ion binding;thiamin pyrophosphate binding;hydro-lyases;catalytics;2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthases; FUNCTIONS IN: 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase activity, hydro-lyase activity, magnesium ion binding, thiamin pyrophosphate binding, catalytic activity; INVOLVED IN: phylloquinone biosynthetic process, photosystem I stabilization; LOCATED IN: chloroplast; EXPRESSED IN: shoot, leaf whorl; CONTAINS InterPro DOMAIN/s: Menaquinone biosynthesis protein MenD (InterPro:IPR004433), Alpha/beta hydrolase fold-1 (InterPro:IPR000073), Mandelate racemase/muconate lactonizing enzyme, C-terminal (InterPro:IPR013342), Thiamine pyrophosphate enzyme, C-terminal TPP-binding (InterPro:IPR011766), Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain (InterPro:IPR012001), O-succinylbenzoic acid (OSB) synthetase, gamma proteobacteria/archaea (InterPro:IPR010196), Mandelate racemase/muconate lactonizing enzyme, conserved site (InterPro:IPR018110); BEST Arabidopsis thaliana protein match is: isochorismate synthase 2 (TAIR:AT1G18870.2); Has 22452 Blast hits to 22188 proteins in 2448 species: Archae - 403; Bacteria - 16894; Metazoa - 237; Fungi - 200; Plants - 484; Viruses - 7; Other Eukaryotes - 4227 (source: NCBI BLink).
Protein Annotations
BioCyc:ARA:AT1G68890-MONOMEREC:2.2.1.9EC:4.2.1.113EC:4.2.99.20eggNOG:COG1165eggNOG:COG1441eggNOG:ENOG410IMYQ
eggNOG:KOG2382EMBL:AC011665EMBL:AK226959EMBL:CP002684EMBL:DQ084385EMBL:DQ084386EnsemblPlants:AT1G68890
EnsemblPlants:AT1G68890.1entrez:843222ESTHER:arath-T6L1.8Gene3D:3.20.20.120Gene3D:3.30.390.10Gene3D:3.40.50.1820Gene3D:3.40.50.970
GeneID:843222Genevisible:Q15KI9GO:GO:0009063GO:GO:0009234GO:GO:0016021GO:GO:0030976GO:GO:0031969
GO:GO:0042372GO:GO:0042550GO:GO:0046872GO:GO:0070204GO:GO:0070205gramene_pathway:2.2.1.9gramene_pathway:3.1.2.2
gramene_pathway:3.1.2.6gramene_pathway:4.2.1.113gramene_pathway:PWY-5148gramene_pathway:PWY-5791HAMAP:MF_01659hmmpanther:PTHR18968hmmpanther:PTHR18968:SF114
HOGENOM:HOG000083101InParanoid:Q15KI9InterPro:IPR000073InterPro:IPR004433InterPro:IPR011766InterPro:IPR012001InterPro:IPR013342
InterPro:IPR018110InterPro:IPR029017InterPro:IPR029035InterPro:IPR029058InterPro:IPR029061InterPro:IPR029065InterPro:IPR032264
KEGG:00130+2.2.1.9KEGG:ath:AT1G68890KO:K14759MEROPS:S33.A36ncoils:CoilOMA:CVVGDISPaxDb:Q15KI9
Pfam:PF00561Pfam:PF02775Pfam:PF02776Pfam:PF13378Pfam:PF16582Pfam:Q15KI9PIR:D96713
PIR:E96713PRIDE:Q15KI9PRO:PR:Q15KI9PROSITE:PS00909ProteinModelPortal:Q15KI9Proteomes:UP000006548RefSeq:NP_177055.2
scanprosite:PS00909SMART:SM00922STRING:3702.AT1G68890.1SUPFAM:SSF51604SUPFAM:SSF52467SUPFAM:SSF52518SUPFAM:SSF53474
SUPFAM:SSF54826TAIR:AT1G68890TIGRfam:TIGR00173TIGRfam:TIGR01927TIGRFAMs:TIGR00173UniGene:At.35470unipathway:UPA00079
unipathway:UPA01057UniProt:Q15KI9
Coordinates (TAIR10) chr1:+:25896988..25906553
Molecular Weight (calculated) 190193.00 Da
IEP (calculated) 6.57
GRAVY (calculated) -0.02
Length 1715 amino acids
Sequence (TAIR10)
(BLAST)
0001: MRSSFLVSNP PFLPSLIPRY SSRKSIRRSR ERFSFPESLR VSLLHGIRRN IEVAQGVQFD GPIMDRDVNL DDDLVVQVCV TRTLPPALTL ELGLESLKEA
0101: IDELKTNPPK SSSGVLRFQV AVPPRAKALF WFCSQPTTSD VFPVFFLSKD TVEPSYKSLY VKEPHGVFGI GNAFAFVHSS SVDSNGHSMI KTFLSDESAM
0201: VTAYGFPDIE FNKYSTVNSK DGSSYFFVPQ IELDEHEEVS ILAVTLAWNE SLSYTVEQTI SSYEKSIFQV SSHFCPNVED HWFKHLKSSL AKLSVEEIHP
0301: LEMEHMGFFT FSGRDQADVK ELKSIQSSCQ FHCKLSPDVV FSNNMLNRET EVSNFLRDEA NINAVWASAI IEECTRLGLT YFCVAPGSRS SHLAIAAANH
0401: PLTTCLACFD ERSLAFHAIG YAKGSLKPAV IITSSGTAVS NLLPAVVEAS EDFLPLLLLT ADRPPELQGV GANQAINQIN HFGSFVRFFF NLPPPTDLIP
0501: VRMVLTTVDS ALHWATGSAC GPVHLNCPFR DPLDGSPTNW SSNCLNGLDM WMSNAEPFTK YFQVQSHKSD GVTTGQITEI LQVIKEAKKG LLLIGAIHTE
0601: DEIWASLLLA KELMWPVVAD VLSGVRLRKL FKPFVEKLTH VFVDHLDHAL FSDSVRNLIE FDVVIQVGSR ITSKRVSQML EKCFPFAYIL VDKHPCRHDP
0701: SHLVTHRVQS NIVQFANCVL KSRFPWRRSK LHGHLQALDG AIAREMSFQI SAESSLTEPY VAHMLSKALT SKSALFIGNS MPIRDVDMYG CSSENSSHVV
0801: DMMLSAELPC QWIQVTGNRG ASGIDGLLSS ATGFAVGCKK RVVCVVGDIS FLHDTNGLAI LKQRIARKPM TILVINNRGG GIFRLLPIAK KTEPSVLNQY
0901: FYTAHDISIE NLCLAHGVRY VHVGTKSELE DALFVPSVEE MDCIVEVESS INANAIVHST LERFARQAAE NSLGIVSASS FLHPMIKNVL LCQVSGIQYS
1001: QYRVKLCDRP TICSDEFSQF HREGFILSLT LEDGSIGYGE VAPLNSNVEN LMDVEGQLQL VLHLMNEAKF SYMLPLLNGS ISSWIWSELG ITASSIFPSV
1101: RCGLEMALLN AMAVRHDSSL LGILHYQKEE NGSAQPHSVQ ICALLDSEGT PLEVAYVARK LVQEGFSAIK LKVGRRVSSV QDALVMQEVR RAVGVQIELR
1201: ADANCRWTFE EAREFGLLVN SCNLKYIEEP VQNKDDLIRF HEETGLPVAL DETLDDFEEC PLRMLTKYTH PGIVAVVIKP SVVGGFENAA LIARWAQQHG
1301: KMAVISAAYE SGLGLSAYIL FASYLEMENV KASTEQKQGT PPSVAHGLGT YRWLSEDVMM NTLGIFRSPY SGFVEGFIAD ASRNLKDVKI NNDVIVRTSK
1401: GIPVRRYELR VDVDGFSHFI RVHDVGENAE GSVALFLHGF LGTGEEWIPI MTGISGSARC ISVDIPGHGR SRVQSHASET QTSPTFSMEM IAEALYKLIE
1501: QITPGKVTIV GYSMGARIAL YMALRFSNKI EGAVVVSGSP GLKDPVARKI RSATDDSKAR MMVDNGLYIF IENWYNGGLW KSLRNHPHFS KIAASRLLHG
1601: DVPSVAKLLS DLSSGRQPSL WEELEDCDTN ISLVFGEKDV KYKQIATRMY REMSKSKKSV NNIIEIVEIP EAGHAVHLES PLRVILALRK FLTRVHNSST
1701: ETELSQKLLL ALKEM
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)