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AT1G63970.1
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
plastid 1.000
ASURE: plastid
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
  • PMID:31186290 (2019): plastid plastid stroma
  • PMID:30783145 (2019): extracellular region plant-type cell wall
  • PMID:29967049 (2018): plastid
  • PMID:24361574 (2014): plastid plastid stroma
  • PMID:24124904 (2013): plastid
  • PMID:23673981 (2013): plastid plastid stroma plastoglobules
  • PMID:21531424 (2011): plastid
  • PMID:20423899 (2010): plastid
  • PMID:20061580 (2010): plastid plastid stroma
  • PMID:18633119 (2008): plastid plastid stroma
  • PMID:18431481 (2008): plastid plastid stroma
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : isoprenoid F
Curator
Summary (TAIR10)
Encodes a protein with 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity. The protein's activity was confirmed by heterologous expression of phenotypic complementation of the E. coli ispF mutant. Plants defective in this gene display an albino lethal phenotype.Homolog of E. coli IspF
Computational
Description (TAIR10)
isoprenoid F (ISPF); FUNCTIONS IN: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity; INVOLVED IN: chlorophyll biosynthetic process, carotenoid biosynthetic process, response to light stimulus, isopentenyl diphosphate biosynthetic process, mevalonate-independent pathway; LOCATED IN: chloroplast stroma, chloroplast; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, conserved site (InterPro:IPR020555), 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, core (InterPro:IPR003526); Has 6473 Blast hits to 6472 proteins in 2098 species: Archae - 0; Bacteria - 4326; Metazoa - 0; Fungi - 4; Plants - 64; Viruses - 0; Other Eukaryotes - 2079 (source: NCBI BLink).
Protein Annotations
BioCyc:ARA:AT1G63970-MONOMERBioCyc:MetaCyc:AT1G63970-MONOMERBioGrid:27921BRENDA:4.6.1.12
ChEMBL:CHEMBL2285351EC:4.6.1.12eggNOG:COG0245eggNOG:ENOG410IGM8
EMBL:AC007764EMBL:AC010852EMBL:AF321531EMBL:AF370154
EMBL:AY059096EMBL:AY085564EMBL:CP002684EnsemblPlants:AT1G63970
EnsemblPlants:AT1G63970.1entrez:842700EvolutionaryTrace:Q9CAK8Gene3D:3.30.1330.50
GeneID:842700Genevisible:Q9CAK8GO:GO:0008685GO:GO:0009507
GO:GO:0009570GO:GO:0015995GO:GO:0016117GO:GO:0019288
GO:GO:0046872gramene_pathway:4.6.1.12gramene_pathway:NONMEVIPP-PWYgramene_plant_reactome:1119464
gramene_plant_reactome:6874931HAMAP:MF_00107hmmpanther:PTHR32125HOGENOM:HOG000239175
InParanoid:Q9CAK8IntAct:Q9CAK8InterPro:IPR003526InterPro:IPR020555
KEGG:00900+4.6.1.12KEGG:ath:AT1G63970KO:K01770OMA:SPHKDAI
PaxDb:Q9CAK8PDB:2PMPPDBsum:2PMPPfam:PF02542
Pfam:Q9CAK8PhylomeDB:Q9CAK8PIR:H96664PRIDE:Q9CAK8
PRO:PR:Q9CAK8PROSITE:PS01350ProteinModelPortal:Q9CAK8Proteomes:UP000006548
RefSeq:NP_564819.2RefSeq:NP_850971.1scanprosite:PS01350SMR:Q9CAK8
STRING:3702.AT1G63970.1SUPFAM:SSF69765TAIR:AT1G63970tair10-symbols:ISPF
tair10-symbols:MECPSTIGRfam:TIGR00151TIGRFAMs:TIGR00151UniGene:At.16455
UniPathway:UPA00056UniProt:Q9CAK8
Coordinates (TAIR10) chr1:-:23738923..23740336
Molecular Weight (calculated) 24813.10 Da
IEP (calculated) 9.22
GRAVY (calculated) -0.03
Length 231 amino acids
Sequence (TAIR10)
(BLAST)
001: MATSSTQLLL SSSSLFHSQI TKKPFLLPAT KIGVWRPKKS LSLSCRPSAS VSAASSAVDV NESVTSEKPT KTLPFRIGHG FDLHRLEPGY PLIIGGIVIP
101: HDRGCEAHSD GDVLLHCVVD AILGALGLPD IGQIFPDSDP KWKGAASSVF IKEAVRLMDE AGYEIGNLDA TLILQRPKIS PHKETIRSNL SKLLGADPSV
201: VNLKAKTHEK VDSLGENRSI AAHTVILLMK K
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)