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AT1G60220.1
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
nucleus 1.000
ASURE: nucleus
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : UB-like protease 1D
Curator
Summary (TAIR10)
Encodes a deSUMOylating enzyme. In vitro it has both peptidase activity and isopeptidase activity: it can cleave C-terminal residues from SUMO to activate it for attachment to a target protein and it can also act on the isopeptide bond between SUMO and another protein. sGFP:OTS1 protein accumulates in the nucleus. Double mutant analysis with ULP1C/OTS2 indicates that these genes are involved in salt stress responses and flowering time regulation. Over-expression of 35S:OTS1 increases salt tolerance and reduces the level of SUMO-conjugated proteins. OTS1 transcript levels do not appear to change in response to salt, but, salt stress reduces the level of OTS1 protein in a proteasome-dependent manner.
Computational
Description (TAIR10)
UB-like protease 1D (ULP1D); CONTAINS InterPro DOMAIN/s: Peptidase C48, SUMO/Sentrin/Ubl1 (InterPro:IPR003653); BEST Arabidopsis thaliana protein match is: Cysteine proteinases superfamily protein (TAIR:AT1G10570.2); Has 2556 Blast hits to 2339 proteins in 246 species: Archae - 0; Bacteria - 12; Metazoa - 1276; Fungi - 441; Plants - 318; Viruses - 13; Other Eukaryotes - 496 (source: NCBI BLink).
Protein Annotations
BioGrid:27541EC:3.4.22.68eggNOG:COG5160eggNOG:KOG0779
EMBL:AC004473EMBL:CP002684EMBL:DQ304543EnsemblPlants:AT1G60220
EnsemblPlants:AT1G60220.1entrez:842317GeneID:842317Genevisible:Q2PS26
GO:GO:0004175GO:GO:0005634GO:GO:0009651GO:GO:0010228
GO:GO:0016607GO:GO:0016926GO:GO:0016929Gramene:AT1G60220.1
hmmpanther:PTHR12606hmmpanther:PTHR12606:SF28HOGENOM:HOG000128552InParanoid:Q2PS26
InterPro:IPR003653KEGG:ath:AT1G60220KO:K16287MEROPS:C48.A04
OMA:KAYIFIPPaxDb:Q2PS26Pfam:PF02902Pfam:Q2PS26
Pfscan:PS50600PhylomeDB:Q2PS26PIR:T02274PRIDE:Q2PS26
PRO:PR:Q2PS26PROSITE:PS50600ProteinModelPortal:Q2PS26Proteomes:UP000006548
RefSeq:NP_176228.3SMR:Q2PS26STRING:3702.AT1G60220.1SUPFAM:SSF54001
TAIR:AT1G60220tair10-symbols:OTS1tair10-symbols:ULP1DUniGene:At.43275
UniGene:At.64986UniProt:Q2PS26
Coordinates (TAIR10) chr1:+:22208332..22211910
Molecular Weight (calculated) 67194.80 Da
IEP (calculated) 5.82
GRAVY (calculated) -0.88
Length 584 amino acids
Sequence (TAIR10)
(BLAST)
001: MTKRKKEVID VDCSEKKDFV IDWSSAMDKE DEVPELEIVN TTKPTPPPPP TFFSDDQTDS PKLLTDRDLD EQLERKKAIL TLGPGLPDKG EKIRLKIADL
101: EEEKQRRVLE GSKMEVDRSS KVVSSTSSGS DVLPQGNAVS KDTSRGNADS KDTSRQGNAD SKEVSRSTFS AVFSKPKTDS QSKKAFGKEL EDLGCERRKH
201: KAGRKPVTRL SNGWRLLPDV GKAEHSAKQF DSGLKESKGN KKSKEPYGKK RPMESSTYSL IDDDDDDDDD DDNDTSGHET PREWSWEKSP SQSSRRRKKS
301: EDTVINVDEE EAQPSTVAEQ AAELPEGLQE DICYPTRDDP HFVQVCLKDL ECLAPREYLT SPVMNFYMRF LQQQISSSNQ ISADCHFFNT YFYKKLSDAV
401: TYKGNDKDAF FVRFRRWWKG IDLFRKAYIF IPIHEDLHWS LVIVCIPDKK DESGLTILHL DSLGLHSRKS IVENVKRFLK DEWNYLNQDD YSLDLPISEK
501: VWKNLPRRIS EAVVQVPQQK NDFDCGPFVL FFIKRFIEEA PQRLKRKDLG MFDKKWFRPD EASALRIKIR NTLIELFRVS DQTE
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)