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AT1G59750.1
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
nucleus 1.000
ASURE: nucleus
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
Description (TAIR10) protein_coding : auxin response factor 1
Curator
Summary (TAIR10)
Encodes a member of the auxin response factor family. ARFs bind to the cis element 5'-TGTCTC-3' ARFs mediate changes in gene expression in response to auxin. ARF's form heterodimers with IAA/AUX genes. ARF1 enhances mutant phenotypes of ARF2 and may act with ARF2 to control aspects of maturation and senescence.ARF1:LUC and 3xHA:ARF1 proteins have a half-life of ~3-4 hours and their degradation is reduced by proteasome inhibitors. 3xHA:ARF1 degradation is not affected by a pre-treatment with IAA. A nuclear-targeted fusion protein containing the middle region of ARF1 linked to LUC:NLS has a similar half-life to the full-length ARF1:LUC construct. The degradation of 3xHA:ARF1 is not affected in an axr6-3 mutant grown at room temperature, although the degradation of AXR2/IAA7 is slowed under these conditions.
Computational
Description (TAIR10)
auxin response factor 1 (ARF1); CONTAINS InterPro DOMAIN/s: Aux/IAA-ARF-dimerisation (InterPro:IPR011525), Transcriptional factor B3 (InterPro:IPR003340), AUX/IAA protein (InterPro:IPR003311), Auxin response factor (InterPro:IPR010525); BEST Arabidopsis thaliana protein match is: auxin response factor 11 (TAIR:AT2G46530.1); Has 2491 Blast hits to 2147 proteins in 119 species: Archae - 0; Bacteria - 28; Metazoa - 9; Fungi - 9; Plants - 2417; Viruses - 4; Other Eukaryotes - 24 (source: NCBI BLink).
Protein Annotations
eggNOG:ENOG410IHVYeggNOG:ENOG410Y8ZKEMBL:AK317214EnsemblPlants:AT1G59750
EnsemblPlants:AT1G59750.1EnsemblPlants:AT1G59750.3entrez:842268ExpressionAtlas:B9DGM9
Gene3D:2.40.330.10GeneID:842268GO:GO:0003677GO:GO:0005634
GO:GO:0006351GO:GO:0006355GO:GO:0009734Gramene:AT1G59750.1
Gramene:AT1G59750.3hmmpanther:PTHR31384hmmpanther:PTHR31384:SF28InterPro:IPR000270
InterPro:IPR003340InterPro:IPR010525InterPro:IPR015300InterPro:IPR033389
KEGG:ath:AT1G59750KO:K14486OMA:EPLNINQPaxDb:B9DGM9
Pfam:PF02309Pfam:PF02362Pfam:PF06507Pfam:Q8L7G0
Pfscan:PS50863Pfscan:PS51745PhylomeDB:B9DGM9PRIDE:B9DGM9
PROSITE:PS50863PROSITE:PS51745ProteinModelPortal:B9DGM9RefSeq:NP_001031208.1
RefSeq:NP_176184.1SMART:SM01019SMR:B9DGM9STRING:3702.AT1G59750.1
SUPFAM:SSF101936SUPFAM:SSF54277TAIR:AT1G59750tair10-symbols:ARF1
UniGene:At.74832UniProt:B9DGM9UniProt:Q8L7G0
Coordinates (TAIR10) chr1:+:21980414..21984193
Molecular Weight (calculated) 73671.40 Da
IEP (calculated) 6.15
GRAVY (calculated) -0.57
Length 665 amino acids
Sequence (TAIR10)
(BLAST)
001: MAASNHSSGK PGGVLSDALC RELWHACAGP LVTLPREGER VYYFPEGHME QLEASMHQGL EQQMPSFNLP SKILCKVINI QRRAEPETDE VYAQITLLPE
101: LDQSEPTSPD APVQEPEKCT VHSFCKTLTA SDTSTHGGFS VLRRHADDCL PPLDMSQQPP WQELVATDLH NSEWHFRHIF RGQPRRHLLT TGWSVFVSSK
201: KLVAGDAFIF LRGENEELRV GVRRHMRQQT NIPSSVISSH SMHIGVLATA AHAITTGTIF SVFYKPRTSR SEFIVSVNRY LEAKTQKLSV GMRFKMRFEG
301: EEAPEKRFSG TIVGVQENKS SVWHDSEWRS LKVQWDEPSS VFRPERVSPW ELEPLVANST PSSQPQPPQR NKRPRPPGLP SPATGPSGPV TPDGVWKSPA
401: DTPSSVPLFS PPAKAATFGH GGNKSFGVSI GSAFWPTNAD SAAESFASAF NNESTEKKQT NGNVCRLFGF ELVENVNVDE CFSAASVSGA VAVDQPVPSN
501: EFDSGQQSEP LNINQSDIPS GSGDPEKSSL RSPQESQSRQ IRSCTKVHMQ GSAVGRAIDL TRSECYEDLF KKLEEMFDIK GELLESTKKW QVVYTDDEDD
601: MMMVGDDPWN EFCGMVRKIF IYTPEEVKKL SPKNKLAVNA RMQLKADAEE NGNTEGRSSS MAGSR
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)