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AT1G58290.1
Subcellular Consensus
(Prediction and Experimental)

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SUBAcon:
plastid 1.000
ASURE: plastid
What is SUBAcon?
What is ASURE?
SUBAcon computations
Experimental Localisations and PPI
FP MS/MS PPI
  • PMID:25900983 (2015): Golgi trans-Golgi network multivesicular body
  • PMID:24872594 (2014): plastid
  • PMID:15028209 (2004): plastid
SUBAcon links
AGI-AGI relationships
Coexpression PPI
Description (TAIR10) protein_coding : Glutamyl-tRNA reductase family protein
Curator
Summary (TAIR10)
Encodes a protein with glutamyl-tRNA reductase (GluTR) activity, catalyzing the NADPH-dependent reduction of Glu-tRNA(Glu) to glutamate 1-semialdehyde (GSA) with the release of free tRNA(Glu). It is involved in the early steps of chlorophyll biosynthesis.
Computational
Description (TAIR10)
HEMA1; FUNCTIONS IN: glutamyl-tRNA reductase activity; INVOLVED IN: chlorophyll biosynthetic process, heme biosynthetic process, response to light stimulus, porphyrin biosynthetic process; LOCATED IN: chloroplast; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase (InterPro:IPR006151), Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, conserved site (InterPro:IPR018214), Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, C-terminal (InterPro:IPR015896), NAD(P)-binding domain (InterPro:IPR016040), Tetrapyrrole biosynthesis, glutamyl-tRNA reductase (InterPro:IPR000343), Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, N-terminal (InterPro:IPR015895); BEST Arabidopsis thaliana protein match is: Glutamyl-tRNA reductase family protein (TAIR:AT1G09940.1); Has 5070 Blast hits to 5064 proteins in 1817 species: Archae - 226; Bacteria - 3676; Metazoa - 1; Fungi - 0; Plants - 227; Viruses - 0; Other Eukaryotes - 940 (source: NCBI BLink).
Protein Annotations
BioCyc:ARA:AT1G58290-MONOMERBioCyc:MetaCyc:AT1G58290-MONOMERBioGrid:27423EC:1.2.1.70eggNOG:COG0373eggNOG:ENOG410IGX5EMBL:AC008051
EMBL:AK226332EMBL:AY072223EMBL:AY096600EMBL:CP002684EMBL:U03774EnsemblPlants:AT1G58290EnsemblPlants:AT1G58290.1
entrez:842198Gene3D:3.40.50.720GeneID:842198Genevisible:P42804GO:GO:0006782GO:GO:0006783GO:GO:0008883
GO:GO:0009507GO:GO:0015995GO:GO:0031969GO:GO:0043234GO:GO:0050661Gramene:AT1G58290.1gramene_pathway:1.2.1.70
gramene_pathway:PWY-5188HAMAP:MF_00087hmmpanther:PTHR13812hmmpanther:PTHR13812:SF20HOGENOM:HOG000109651InParanoid:P42804IntAct:P42804
InterPro:IPR000343InterPro:IPR006151InterPro:IPR015895InterPro:IPR015896InterPro:IPR016040InterPro:IPR018214KEGG:00860+1.2.1.70
KEGG:ath:AT1G58290KO:K02492MINT:MINT-8300920OMA:CELKAMEPaxDb:P42804PDB:4N7RPDB:4YVQ
PDB:5CHEPDBsum:4N7RPDBsum:4YVQPDBsum:5CHEPfam:P42804Pfam:PF00745Pfam:PF01488
Pfam:PF05201PhylomeDB:P42804PIR:E96616PRIDE:P42804PRO:PR:P42804PROSITE:PS00747ProteinModelPortal:P42804
Proteomes:UP000006548RefSeq:NP_176125.1scanprosite:PS00747SMR:P42804STRING:3702.AT1G58290.1SUPFAM:0038205SUPFAM:0047033
SUPFAM:SSF51735SUPFAM:SSF69075SUPFAM:SSF69742TAIR:AT1G58290tair10-symbols:HEMA1TIGRfam:TIGR01035TIGRFAMs:TIGR01035
UniGene:At.241UniPathway:UPA00251UniPathway:UPA00668UniProt:P42804
Coordinates (TAIR10) chr1:-:21624028..21626051
Molecular Weight (calculated) 59518.80 Da
IEP (calculated) 7.91
GRAVY (calculated) -0.20
Length 543 amino acids
Sequence (TAIR10)
(BLAST)
001: MAVSSAFVGC PKLETLLNHH NLSPSSSSSS SVSQTPLGLN GVRVLPKNNR TRRGLIQKAR CELSASSDSA SNAASISALE QLKNSAADRY TKERSSIVVI
101: GLSIHTAPVE MREKLAIPEA EWPRAIAELC GLNHIEEAAV LSTCNRMEIY VLALSQHRGV KEVTEWMSKT SGIPVSEICQ HRFLLYNKDA TQHIFEVSAG
201: LDSLVLGEGQ ILAQVKQVVK VGQGVNGFGR NISGLFKHAI TVGKRVRTET NIASGAVSVS SAAVELALMK LPQSSNVSAR MCVIGAGKMG KLVIKHLMAK
301: GCTKVVVVNR SEERVSAIRE EMPGIEIIYR PLDEMLACAS EADVVFTSTA SETPLFLKEH VENLPQASPE VGGLRHFVDI SVPRNVGSCV GEVETARVYN
401: VDDLKEVVAA NKEDRMRKAM EAQTIITEES TQFEAWRDSL ETVPTIKKLR AYAERIRVAE LEKCMSKMGD DINKKTTRAV DDLSRGIVNR FLHGPMQHLR
501: CDGSDSRTLS ETLENMHALN RMYGLEKDIL EEKLKAMAEQ QQK
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)