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AT1G53500.1
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
cytosol 1.000
ASURE: cytosol
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
  • PMID:31520498 (2020): mitochondrion
  • PMID:30961429 (2019): nucleus
  • PMID:30783145 (2019): extracellular region plant-type cell wall
  • PMID:28865150 (2017): extracellular region plant-type cell wall
  • PMID:21166475 (2011): cytosol
  • PMID:19334764 (2009): plasma membrane
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : NAD-dependent epimerase/dehydratase family protein
Curator
Summary (TAIR10)
encodes a putative NDP-L-rhamnose synthase, an enzyme required for the synthesis of the pectin rhamnogalacturonan I, the major component of Arabidopsis mucilage. Gene is involved in seed coat mucilage cell development. Mutant analyses suggest that MUM4 is required for complete mucilage synthesis, cytoplasmic rearrangement and seed coat development.
Computational
Description (TAIR10)
MUCILAGE-MODIFIED 4 (MUM4); FUNCTIONS IN: UDP-4-keto-rhamnose-4-keto-reductase activity, UDP-4-keto-6-deoxy-glucose-3,5-epimerase activity, catalytic activity, UDP-glucose 4,6-dehydratase activity, UDP-L-rhamnose synthase activity; INVOLVED IN: seed coat development, UDP-rhamnose biosynthetic process, mucilage biosynthetic process, metabolic process; LOCATED IN: soluble fraction; EXPRESSED IN: 28 plant structures; EXPRESSED DURING: 17 growth stages; CONTAINS InterPro DOMAIN/s: NAD-dependent epimerase/dehydratase (InterPro:IPR001509), NAD(P)-binding domain (InterPro:IPR016040), dTDP-4-dehydrorhamnose reductase (InterPro:IPR005913); BEST Arabidopsis thaliana protein match is: rhamnose biosynthesis 3 (TAIR:AT3G14790.1); Has 53909 Blast hits to 53717 proteins in 3029 species: Archae - 941; Bacteria - 31079; Metazoa - 1146; Fungi - 539; Plants - 1500; Viruses - 107; Other Eukaryotes - 18597 (source: NCBI BLink).
Protein Annotations
BioCyc:MetaCyc:AT1G53500-MONOMERBioGrid:27010EC:1.1.1.-EC:4.2.1.76
EC:5.1.3.-eggNOG:COG1088eggNOG:KOG0747EMBL:AC018748
EMBL:AC024260EMBL:AJ565874EMBL:AY328518EMBL:CP002684
EnsemblPlants:AT1G53500EnsemblPlants:AT1G53500.1entrez:841785Gene3D:3.40.50.720
GeneID:841785Genevisible:Q9LPG6GO:GO:0005829GO:GO:0008460
GO:GO:0010192GO:GO:0010214GO:GO:0010253GO:GO:0010280
GO:GO:0010489GO:GO:0010490GO:GO:0050377Gramene:AT1G53500.1
gramene_pathway:4.2.1.76gramene_pathway:PWY-3261hmmpanther:PTHR10366hmmpanther:PTHR10366:SF385
HOGENOM:HOG000167988InParanoid:Q9LPG6InterPro:IPR005888InterPro:IPR016040
InterPro:IPR029903iPTMnet:Q9LPG6KEGG:00521+4.2.1.46KEGG:00523+4.2.1.46
KEGG:ath:AT1G53500KO:K12450MINT:MINT-8067929OMA:HKGEIGH
PaxDb:Q9LPG6Pfam:PF04321Pfam:PF16363Pfam:Q9LPG6
PhylomeDB:Q9LPG6PIR:B96575PRIDE:Q9LPG6PRO:PR:Q9LPG6
ProteinModelPortal:Q9LPG6Proteomes:UP000006548RefSeq:NP_564633.2SMR:Q9LPG6
STRING:3702.AT1G53500.1SUPFAM:SSF51735TAIR:AT1G53500tair10-symbols:ATMUM4
tair10-symbols:ATRHM2tair10-symbols:MUM4tair10-symbols:RHM2TIGRfam:TIGR01181
TIGRFAMs:TIGR01181UniGene:At.20215UniProt:Q9LPG6
Coordinates (TAIR10) chr1:-:19967157..19969239
Molecular Weight (calculated) 75229.60 Da
IEP (calculated) 6.41
GRAVY (calculated) -0.40
Length 667 amino acids
Sequence (TAIR10)
(BLAST)
001: MDDTTYKPKN ILITGAAGFI ASHVANRLIR NYPDYKIVVL DKLDYCSDLK NLDPSFSSPN FKFVKGDIAS DDLVNYLLIT ENIDTIMHFA AQTHVDNSFG
101: NSFEFTKNNI YGTHVLLEAC KVTGQIRRFI HVSTDEVYGE TDEDAAVGNH EASQLLPTNP YSATKAGAEM LVMAYGRSYG LPVITTRGNN VYGPNQFPEK
201: MIPKFILLAM SGKPLPIHGD GSNVRSYLYC EDVAEAFEVV LHKGEIGHVY NVGTKRERRV IDVARDICKL FGKDPESSIQ FVENRPFNDQ RYFLDDQKLK
301: KLGWQERTNW EDGLKKTMDW YTQNPEWWGD VSGALLPHPR MLMMPGGRLS DGSSEKKDVS SNTVQTFTVV TPKNGDSGDK ASLKFLIYGK TGWLGGLLGK
401: LCEKQGITYE YGKGRLEDRA SLVADIRSIK PTHVFNAAGL TGRPNVDWCE SHKPETIRVN VAGTLTLADV CRENDLLMMN FATGCIFEYD ATHPEGSGIG
501: FKEEDKPNFF GSFYSKTKAM VEELLREFDN VCTLRVRMPI SSDLNNPRNF ITKISRYNKV VDIPNSMTVL DELLPISIEM AKRNLRGIWN FTNPGVVSHN
601: EILEMYKNYI EPGFKWSNFT VEEQAKVIVA ARSNNEMDGS KLSKEFPEML SIKESLLKYV FEPNKRT
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)