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AT1G50430.1
Subcellular Consensus
(Prediction and Experimental)

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SUBAcon:
endoplasmic reticulum 0.976
What is SUBAcon?
What is ASURE?
SUBAcon computations
Predictors External Curations
AmiGO : endoplasmic reticulum 8631902
SwissProt : endoplasmic reticulum 16381842
TAIR : plasma membrane 17317660
TAIR : endoplasmic reticulum 8631902
Experimental Localisations and PPI
FP MS/MS PPI
  • PMID:23409184 (2013): endoplasmic reticulum
  • PMID:23409184 (2013): plasma membrane
  • PMID:25900983 (2015): Golgi Golgi apparatus Golgi membrane
  • PMID:25900983 (2015): Golgi trans-Golgi network
  • PMID:22430844 (2012): Golgi
  • PMID:17317660 (2007): plasma membrane
SUBAcon links
AGI-AGI relationships
Coexpression PPI
Description (TAIR10) protein_coding : Ergosterol biosynthesis ERG4/ERG24 family
Curator
Summary (TAIR10)
Mutants are defective in Brassinosteroid biosynthesis (delta7-sterol-C7 reduction step) and have a dwarf phenotype.
Computational
Description (TAIR10)
DWARF 5 (DWF5); FUNCTIONS IN: sterol delta7 reductase activity; INVOLVED IN: sterol biosynthetic process, unidimensional cell growth, brassinosteroid biosynthetic process; LOCATED IN: integral to endoplasmic reticulum membrane, plasma membrane; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Sterol reductase, conserved site (InterPro:IPR018083), Ergosterol biosynthesis ERG4/ERG24 (InterPro:IPR001171); BEST Arabidopsis thaliana protein match is: Ergosterol biosynthesis ERG4/ERG24 family (TAIR:AT3G52940.1); Has 989 Blast hits to 986 proteins in 209 species: Archae - 0; Bacteria - 51; Metazoa - 267; Fungi - 416; Plants - 150; Viruses - 3; Other Eukaryotes - 102 (source: NCBI BLink).
Protein Annotations
BioCyc:ARA:AT1G50430-MONOMERBioCyc:ARA:GQT-228-MONOMERBioCyc:MetaCyc:AT1G50430-MONOMERBioGrid:26690BRENDA:1.3.1.21EC:1.3.1.21eggNOG:ENOG410XP67
eggNOG:KOG1435EMBL:AC012561EMBL:AF239701EMBL:AY099589EMBL:BT000245EMBL:CP002684EMBL:U49398
EnsemblPlants:AT1G50430EnsemblPlants:AT1G50430.1entrez:841465ExpressionAtlas:Q0WU95ExpressionAtlas:Q9LDU6GeneID:841465Genevisible:Q9LDU6
GO:GO:0005789GO:GO:0005794GO:GO:0005886GO:GO:0006695GO:GO:0009918GO:GO:0016021GO:GO:0016132
GO:GO:0047598gramene_pathway:1.3.1.21gramene_pathway:PWY-2541gramene_pathway:PWY-6663gramene_plant_reactome:1119370gramene_plant_reactome:6876419hmmpanther:PTHR21257
hmmpanther:PTHR21257:SF34HOGENOM:HOG000193296InParanoid:Q9LDU6IntAct:Q9LDU6InterPro:IPR001171InterPro:IPR018083OMA:ITHALWF
PaxDb:Q0WU95PaxDb:Q9LDU6Pfam:PF01222Pfam:Q9LDU6PhylomeDB:Q0WU95PhylomeDB:Q9LDU6PIR:F96540
PRIDE:Q9LDU6PRO:PR:Q9LDU6PROSITE:PS01017PROSITE:PS01018ProteinModelPortal:Q9LDU6Proteomes:UP000006548Reactome:R-ATH-6807047
Reactome:R-ATH-6807062RefSeq:NP_175460.1scanprosite:PS01017scanprosite:PS01018SMR:Q9LDU6STRING:3702.AT1G50430.1SwissPalm:Q9LDU6
TAIR:AT1G50430tair10-symbols:7REDtair10-symbols:DWF5tair10-symbols:LEtair10-symbols:PAtair10-symbols:ST7RTMHMM:TMhelix
UniGene:At.25165UniPathway:UPA00062UniProt:Q0WU95UniProt:Q9LDU6
Coordinates (TAIR10) chr1:-:18682175..18685555
Molecular Weight (calculated) 49593.70 Da
IEP (calculated) 8.43
GRAVY (calculated) 0.37
Length 432 amino acids
Sequence (TAIR10)
(BLAST)
001: MAETVHSPIV TYASMLSLLA FCPPFVILLW YTMVHQDGSV TQTFGFFWEN GVQGLINIWP RPTLIAWKII FCYGAFEAIL QLLLPGKRVE GPISPAGNRP
101: VYKANGLAAY FVTLATYLGL WWFGIFNPAI VYDHLGEIFS ALIFGSFIFC VLLYIKGHVA PSSSDSGSCG NLIIDFYWGM ELYPRIGKSF DIKVFTNCRF
201: GMMSWAVLAV TYCIKQYEIN GKVSDSMLVN TILMLVYVTK FFWWEAGYWN TMDIAHDRAG FYICWGCLVW VPSVYTSPGM YLVNHPVELG TQLAIYILVA
301: GILCIYINYD CDRQRQEFRR TNGKCLVWGR APSKIVASYT TTSGETKTSL LLTSGWWGLA RHFHYVPEIL SAFFWTVPAL FDNFLAYFYV IFLTLLLFDR
401: AKRDDDRCRS KYGKYWKLYC EKVKYRIIPG IY
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)