AT1G50030.1
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Subcellular Consensus
(Prediction and Experimental) min:  :max.
SUBAcon:nucleus 1.000 What is SUBAcon? |
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| Experimental Localisations and PPI |
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SUBAcon links
AGI-AGI relationships |
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| Description (TAIR10) | protein_coding : target of rapamycin | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Curator Summary (TAIR10) |
Related to TOR proteins from yeast and mammals, regulators of cell growth in response to nutrient availability. TOR proteins belong to the family of phosphatidylinositol 3-kinase and are targets of the antiproliferative drug rapamycin. AtTOR binds the yeast FKBP12 protein in the presence of Rapamycin, is involved in embryogenesis and is expressed in embryos, endosperm and meristems. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Computational Description (TAIR10) |
target of rapamycin (TOR); FUNCTIONS IN: protein binding, 1-phosphatidylinositol-3-kinase activity; INVOLVED IN: embryo development ending in seed dormancy; LOCATED IN: chloroplast; EXPRESSED IN: 28 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Phosphatidylinositol 3-/4-kinase, catalytic (InterPro:IPR000403), Armadillo-like helical (InterPro:IPR011989), FKBP12-rapamycin-associated protein, FKBP12-rapamycin-binding (InterPro:IPR009076), Protein kinase-like domain (InterPro:IPR011009), PIK-related kinase, FAT (InterPro:IPR003151), PIK-related kinase (InterPro:IPR014009), Armadillo-type fold (InterPro:IPR016024), PIK-related kinase, FATC (InterPro:IPR003152), Phosphatidylinositol 3/4-kinase, conserved site (InterPro:IPR018936); BEST Arabidopsis thaliana protein match is: Ataxia telangiectasia-mutated and RAD3-related (TAIR:AT5G40820.1); Has 4645 Blast hits to 4114 proteins in 299 species: Archae - 0; Bacteria - 46; Metazoa - 1929; Fungi - 1123; Plants - 507; Viruses - 4; Other Eukaryotes - 1036 (source: NCBI BLink). | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Protein Annotations |
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| Coordinates (TAIR10) | chr1:-:18522626..18539619 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Molecular Weight (calculated) | 279206.00 Da | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| IEP (calculated) | 6.82 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| GRAVY (calculated) | -0.14 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Length | 2481 amino acids | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Sequence (TAIR10) (BLAST) |
0001: MSTSSQSFVA GRPASMASPS QSHRFCGPSA TASGGGSFDT LNRVIADLCS RGNPKEGAPL AFRKHVEEAV RDLSGEASSR FMEQLYDRIA NLIESTDVAE 0101: NMGALRAIDE LTEIGFGENA TKVSRFAGYM RTVFELKRDP EILVLASRVL GHLARAGGAM TSDEVEFQMK TAFDWLRVDR VEYRRFAAVL ILKEMAENAS 0201: TVFNVHVPEF VDAIWVALRD PQLQVRERAV EALRACLRVI EKRETRWRVQ WYYRMFEATQ DGLGRNAPVH SIHGSLLAVG ELLRNTGEFM MSRYREVAEI 0301: VLRYLEHRDR LVRLSITSLL PRIAHFLRDR FVTNYLTICM NHILTVLRIP AERASGFIAL GEMAGALDGE LIHYLPTIMS HLRDAIAPRK GRPLLEAVAC 0401: VGNIAKAMGS TVETHVRDLL DVMFSSSLSS TLVDALDQIT ISIPSLLPTV QDRLLDCISL VLSKSHYSQA KPPVTIVRGS TVGMAPQSSD PSCSAQVQLA 0501: LQTLARFNFK GHDLLEFARE SVVVYLDDED AATRKDAALC CCRLIANSLS GITQFGSSRS TRAGGRRRRL VEEIVEKLLR TAVADADVTV RKSIFVALFG 0601: NQCFDDYLAQ ADSLTAIFAS LNDEDLDVRE YAISVAGRLS EKNPAYVLPA LRRHLIQLLT YLELSADNKC REESAKLLGC LVRNCERLIL PYVAPVQKAL 0701: VARLSEGTGV NANNNIVTGV LVTVGDLARV GGLAMRQYIP ELMPLIVEAL MDGAAVAKRE VAVSTLGQVV QSTGYVVTPY KEYPLLLGLL LKLLKGDLVW 0801: STRREVLKVL GIMGALDPHV HKRNQQSLSG SHGEVPRGTG DSGQPIPSID ELPVELRPSF ATSEDYYSTV AINSLMRILR DASLLSYHKR VVRSLMIIFK 0901: SMGLGCVPYL PKVLPELFHT VRTSDENLKD FITWGLGTLV SIVRQHIRKY LPELLSLVSE LWSSFTLPGP IRPSRGLPVL HLLEHLCLAL NDEFRTYLPV 1001: ILPCFIQVLG DAERFNDYTY VPDILHTLEV FGGTLDEHMH LLLPALIRLF KVDAPVAIRR DAIKTLTRVI PCVQVTGHIS ALVHHLKLVL DGKNDELRKD 1101: AVDALCCLAH ALGEDFTIFI ESIHKLLLKH RLRHKEFEEI HARWRRREPL IVATTATQQL SRRLPVEVIR DPVIENEIDP FEEGTDRNHQ VNDGRLRTAG 1201: EASQRSTKED WEEWMRHFSI ELLKESPSPA LRTCAKLAQL QPFVGRELFA AGFVSCWAQL NESSQKQLVR SLEMAFSSPN IPPEILATLL NLAEFMEHDE 1301: KPLPIDIRLL GALAEKCRVF AKALHYKEME FEGPRSKRMD ANPVAVVEAL IHINNQLHQH EAAVGILTYA QQHLDVQLKE SWYEKLQRWD DALKAYTLKA 1401: SQTTNPHLVL EATLGQMRCL AALARWEELN NLCKEYWSPA EPSARLEMAP MAAQAAWNMG EWDQMAEYVS RLDDGDETKL RGLASPVSSG DGSSNGTFFR 1501: AVLLVRRAKY DEAREYVERA RKCLATELAA LVLESYERAY SNMVRVQQLS ELEEVIEYYT LPVGNTIAEE RRALIRNMWT QRIQGSKRNV EVWQALLAVR 1601: ALVLPPTEDV ETWLKFASLC RKSGRISQAK STLLKLLPFD PEVSPENMQY HGPPQVMLGY LKYQWSLGEE RKRKEAFTKL QILTRELSSV PHSQSDILAS 1701: MVSSKGANVP LLARVNLKLG TWQWALSSGL NDGSIQEIRD AFDKSTCYAP KWAKAWHTWA LFNTAVMSHY ISRGQIASQY VVSAVTGYFY SIACAANAKG 1801: VDDSLQDILR LLTLWFNHGA TADVQTALKT GFSHVNINTW LVVLPQIIAR IHSNNRAVRE LIQSLLIRIG ENHPQALMYP LLVACKSISN LRRAAAQEVV 1901: DKVRQHSGAL VDQAQLVSHE LIRVAILWHE MWHEALEEAS RLYFGEHNIE GMLKVLEPLH DMLDEGVKKD STTIQERAFI EAYRHELKEA HECCCNYKIT 2001: GKDAELTQAW DLYYHVFKRI DKQLASLTTL DLESVSPELL LCRDLELAVP GTYRADAPVV TISSFSRQLV VITSKQRPRK LTIHGNDGED YAFLLKGHED 2101: LRQDERVMQL FGLVNTLLEN SRKTAEKDLS IQRYSVIPLS PNSGLIGWVP NCDTLHHLIR EHRDARKIIL NQENKHMLSF APDYDNLPLI AKVEVFEYAL 2201: ENTEGNDLSR VLWLKSRSSE VWLERRTNYT RSLAVMSMVG YILGLGDRHP SNLMLHRYSG KILHIDFGDC FEASMNREKF PEKVPFRLTR MLVKAMEVSG 2301: IEGNFRSTCE NVMQVLRTNK DSVMAMMEAF VHDPLINWRL FNFNEVPQLA LLGNNNPNAP ADVEPDEEDE DPADIDLPQP QRSTREKEIL QAVNMLGDAN 2401: EVLNERAVVV MARMSHKLTG RDFSSSAIPS NPIADHNNLL GGDSHEVEHG LSVKVQVQKL INQATSHENL CQNYVGWCPF W |
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Citation
If you find this resource useful please cite one of the following publications:
Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)
Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)