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AT1G49040.1
Subcellular Consensus
(Prediction and Experimental)

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SUBAcon:
plasma membrane 1.000
What is SUBAcon?
What is ASURE?
SUBAcon computations
Experimental Localisations and PPI
FP MS/MS PPI
  • PMID:26781341 (2016): plasma membrane
  • PMID:25900983 (2015): Golgi
  • PMID:25900983 (2015): Golgi trans-Golgi network
  • PMID:25900983 (2015): Golgi trans-Golgi network multivesicular body
  • PMID:24134884 (2013): cytoskeleton microtubules
  • PMID:21433285 (2011): plasma membrane
  • PMID:19334764 (2009): plasma membrane
SUBAcon links
AGI-AGI relationships
Coexpression PPI
Description (TAIR10) protein_coding : stomatal cytokinesis defective / SCD1 protein (SCD1)
Curator
Summary (TAIR10)
Encodes soluble protein containing N-terminal DENN domain and eight C-terminal WD-40 repeats. Involved in cytokinesis of guard mother cells and leaf epidermal cells. The overall growth and development of mutant plants is severely affected, they are smaller than wt, with defects in seedling development, leaf expansion and flower morphology which renders the mutant conditionally sterile.
Computational
Description (TAIR10)
STOMATAL CYTOKINESIS-DEFECTIVE 1 (SCD1); CONTAINS InterPro DOMAIN/s: WD40 repeat 2 (InterPro:IPR019782), dDENN (InterPro:IPR005112), WD40 repeat, conserved site (InterPro:IPR019775), WD40 repeat (InterPro:IPR001680), G-protein beta WD-40 repeat, region (InterPro:IPR020472), uDENN (InterPro:IPR005113), WD40 repeat-like-containing domain (InterPro:IPR011046), DENN (InterPro:IPR001194), WD40-repeat-containing domain (InterPro:IPR017986), WD40/YVTN repeat-like-containing domain (InterPro:IPR015943), WD40 repeat, subgroup (InterPro:IPR019781); BEST Arabidopsis thaliana protein match is: Transducin/WD40 repeat-like superfamily protein (TAIR:AT5G23430.2); Has 71080 Blast hits to 32273 proteins in 828 species: Archae - 56; Bacteria - 8068; Metazoa - 28161; Fungi - 15613; Plants - 9829; Viruses - 0; Other Eukaryotes - 9353 (source: NCBI BLink).
Protein Annotations
eggNOG:ENOG410XQMXeggNOG:KOG2127EMBL:AC016041EMBL:AY082605EMBL:CP002684EnsemblPlants:AT1G49040EnsemblPlants:AT1G49040.1
entrez:841327ExpressionAtlas:Q8RXA7Gene3D:2.130.10.10GeneID:841327Genevisible:Q8RXA7GO:GO:0000911GO:GO:0005886
GO:GO:0009825GO:GO:0010235GO:GO:0030136GO:GO:0040008GO:GO:0045824GO:GO:0080008hmmpanther:PTHR22844
hmmpanther:PTHR22844:SF202HOGENOM:HOG000029412InParanoid:Q8RXA7InterPro:IPR001194InterPro:IPR001680InterPro:IPR005112InterPro:IPR005113
InterPro:IPR015943InterPro:IPR017986InterPro:IPR019775InterPro:IPR020472iPTMnet:Q8RXA7OMA:WGEDHDLPaxDb:Q8RXA7
Pfam:PF00400Pfam:PF02141Pfam:PF03456Pfam:Q8RXA7Pfscan:PS50082Pfscan:PS50211Pfscan:PS50294
Pfscan:PS50946Pfscan:PS50947PhylomeDB:Q8RXA7PIR:H96527PRIDE:Q8RXA7PRINTS:PR00320PRO:PR:Q8RXA7
PROSITE:PS00678PROSITE:PS50082PROSITE:PS50211PROSITE:PS50294PROSITE:PS50946PROSITE:PS50947ProteinModelPortal:Q8RXA7
Proteomes:UP000006548RefSeq:NP_850959.1scanprosite:PS00678SMART:SM00320SMART:SM00799SMART:SM00800SMART:SM00801
SMR:Q8RXA7STRING:3702.AT1G49040.1SUPFAM:SSF50978TAIR:AT1G49040tair10-symbols:SCD1UniGene:At.38309UniProt:Q8RXA7
Coordinates (TAIR10) chr1:-:18139419..18148826
Molecular Weight (calculated) 131600.00 Da
IEP (calculated) 5.54
GRAVY (calculated) -0.16
Length 1187 amino acids
Sequence (TAIR10)
(BLAST)
0001: MGRIFEYFVV CGLGPEMRTV DGDLGFHGMQ TFYLPALLDQ FPPTDQSPYP APPPQLPTCV LPAGVEFHSS GFVSSDPASF PRSYPIVLTE GDGSKIFVSC
0101: IAFRDRVCED IIEAYRLPPN TYADKCICLV SHAPNFRVLR NSLEEIFVLC FSSEGSCKPL WDIIAYMVSN VPLPTPGKDR VLFAVENCLL SVEAPPEDSL
0201: PQADISLQPL VQCLDVDNLI KLFTSVLVER RILIRSNKYS LLTLVSESIC HLIYPFRWLQ VYIPLLFFSG VDYIDAPTPY MMGLHSDVDT SNLAMDGVVV
0301: VDLDINQITT SEEIPQIPEP EFSTLRNDIL KLLHPNVVAI DQLKGFGNSV EQCPKSLSKP WGEDHDLQLR VIFLKCFASI LGGYRNFIEN KVFSTDAFLK
0401: RRSRSTNQPP EPMLVQFLGS FAFLDYLERR LSSDEKSTNL LEKLQDAVGR GQDAMSILPK SSMEPEIITI AEPEVEESAT RYTYDRFPAS VRSEEQEEKR
0501: KQILAAASGA LESNGRHPPS SPPGKNTKED NFSSMERAAE RERMVLDIQV KLQGLWLRLL KLGSDEDPLS SFEYGTILAL IESDAEGIGG SGFIECIREH
0601: LYSGWHGQLS EEQFIAVKEL LKMAVGRAAS RSDLSTVRDA LEVSAEMFKK DANNVSDYVQ RHLISIPIWE ELRFWEGYFE YLMEQPANES VNYATLVTAR
0701: LIIVASHMAG LGLPDTEAWN MIETIAEKQK LGYKLLIKLR GFLSHVQQLR VGYWGASSFK QQAISAGLPS PRPKDVSVSD ETQQPSEASG RSWVQSMFSR
0801: DTASRANSFS RVRKWVSDNA SSDITAAAQK KIQTNVRVLK GHGGAVTALH SVTRREVCDL VGDREDAGFF ISGSTDCLVK IWDPSLRGSE LRATLKGHTG
0901: TVRAISSDRG KIVSGSDDLS VIVWDKQTTQ LLEELKGHDS QVSCVKMLSG ERVLTAAHDG TVKMWDVRTD MCVATVGRCS SAILSLEYDD STGILAAAGR
1001: DTVANIWDIR SGKQMHKLKG HTKWIRSIRM VEDTLITGSD DWTARVWSVS RGSCDAVLAC HAGPVQSVEY SPFDKGIITG SADGLLRFWE NDEGGIKCVK
1101: NITLHSSSIL SINAGENWLG IGAADNSMSL FHRPSNAGTK VSGWQLYRVP QRTAAVVRCV ASDLERKRIC SGGRNGVLRL WDATINI
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)