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AT1G47290.1
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
golgi 0.407
plasma membrane 0.327
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
Description (TAIR10) protein_coding : 3beta-hydroxysteroid-dehydrogenase/decarboxylase isoform 1
Curator
Summary (TAIR10)
Encodes an enzyme with 3&#946;-hydroxysteroid dehydrogenase/C4-decarboxylase activity <i>in vitro</i>. The activity of the enzyme was determined using microsomal extracts of yeast overexpressing the <i>Arabidopsis</i> gene. Cytosolic fractions failed to be associated to the activity, leading to the speculation that the enzyme is membrane-bound.
Computational
Description (TAIR10)
3beta-hydroxysteroid-dehydrogenase/decarboxylase isoform 1 (3BETAHSD/D1); FUNCTIONS IN: 3-beta-hydroxy-delta5-steroid dehydrogenase activity, sterol-4-alpha-carboxylate 3-dehydrogenase (decarboxylating) activity; INVOLVED IN: steroid biosynthetic process, metabolic process; LOCATED IN: membrane; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: 3-beta hydroxysteroid dehydrogenase/isomerase (InterPro:IPR002225), NAD(P)-binding domain (InterPro:IPR016040); BEST Arabidopsis thaliana protein match is: 3beta-hydroxysteroid-dehydrogenase/decarboxylase isoform 2 (TAIR:AT2G26260.1); Has 24441 Blast hits to 24428 proteins in 2873 species: Archae - 619; Bacteria - 15419; Metazoa - 693; Fungi - 529; Plants - 1563; Viruses - 132; Other Eukaryotes - 5486 (source: NCBI BLink).
Protein Annotations
EnsemblPlants:AT1G47290EnsemblPlants:AT1G47290.1entrez:841132gramene_pathway:1.1.1.-
gramene_pathway:1.1.1.170gramene_pathway:PWY-6663gramene_pathway:PWY66-341hmmpanther:PTHR10366
hmmpanther:PTHR10366:SF471Pfam:PF01073tair10-symbols:3BETAHSD/D1tair10-symbols:AT3BETAHSD/D1
Coordinates (TAIR10) chr1:+:17336121..17339030
Molecular Weight (calculated) 41910.80 Da
IEP (calculated) 8.62
GRAVY (calculated) -0.06
Length 382 amino acids
Sequence (TAIR10)
(BLAST)
001: MVMEVTETER WCVVTGGRGF AARHLVEMLV RYQMFHVRIA DLAPAIVLNP HEETGILGEA IRSGRVQYVS ADLRNKTQVV KGFQGAEVVF HMAAPDSSIN
101: NHQLQYSVNV QGTTNVIDAC IEVGVKRLIY TSSPSVVFDG VHGTLNADES LPYPPKHNDS YSATKAEGEA LILKANGRSG LLTCCIRPSS IFGPGDKLMV
201: PSLVTAARAG KSKFIIGDGS NFYDFTYVEN VVHAHVCAER ALASGGEVCA KAAGQAYFIT NMEPIKFWEF MSQLLEGLGY ERPSIKIPAS LMMPIAYLVE
301: LAYKLLGPYG MKVPVLTPSR VRLLSCNRTF DSSKAKDRLG YSPVVPLQEG IKRTIDSFSH LKAQNQPKTE EKMKVFGSKK ID
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)