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AT1G44900.1
Subcellular Consensus
(Prediction and Experimental)

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SUBAcon:
nucleus 1.000
What is SUBAcon?
What is ASURE?
SUBAcon computations
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : minichromosome maintenance (MCM2/3/5) family protein
Curator
Summary (TAIR10)
Encodes MCM2 (MINICHROMOSOME MAINTENANCE 2), a protein essential to embryo development. Overexpression results in altered root meristem function.
Computational
Description (TAIR10)
MINICHROMOSOME MAINTENANCE 2 (MCM2); FUNCTIONS IN: DNA-dependent ATPase activity, DNA binding, ATP binding; INVOLVED IN: in 7 processes; LOCATED IN: nuclear chromatin; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 12 growth stages; CONTAINS InterPro DOMAIN/s: Nucleic acid-binding, OB-fold-like (InterPro:IPR016027), Nucleic acid-binding, OB-fold (InterPro:IPR012340), DNA-dependent ATPase MCM (InterPro:IPR001208), DNA-dependent ATPase MCM, conserved site (InterPro:IPR018525), MCM protein 2 (InterPro:IPR008045), MCM protein 2, N-terminal (InterPro:IPR021092); BEST Arabidopsis thaliana protein match is: Minichromosome maintenance (MCM2/3/5) family protein (TAIR:AT2G16440.1); Has 6038 Blast hits to 5672 proteins in 1024 species: Archae - 381; Bacteria - 1139; Metazoa - 1602; Fungi - 1087; Plants - 469; Viruses - 28; Other Eukaryotes - 1332 (source: NCBI BLink).
Protein Annotations
BioGrid:26281EC:3.6.4.12eggNOG:COG1241eggNOG:KOG0477EMBL:AC020576EMBL:AK227536EMBL:CP002684
EMBL:Y08301EnsemblPlants:AT1G44900EnsemblPlants:AT1G44900.1entrez:841056ExpressionAtlas:Q9LPD9Gene3D:2.40.50.140Gene3D:3.40.50.300
GeneID:841056Genevisible:Q9LPD9GO:GO:0000347GO:GO:0003677GO:GO:0003678GO:GO:0005524GO:GO:0005829
GO:GO:0006268GO:GO:0006270GO:GO:0007049GO:GO:0009793GO:GO:0010082GO:GO:0016032GO:GO:0042127
GO:GO:0042555GO:GO:0046872GO:GO:0048364hmmpanther:PTHR11630hmmpanther:PTHR11630:SF44HOGENOM:HOG000224124InParanoid:Q9LPD9
IntAct:Q9LPD9InterPro:IPR001208InterPro:IPR008045InterPro:IPR012340InterPro:IPR018525InterPro:IPR027417InterPro:IPR027925
InterPro:IPR031327iPTMnet:Q9LPD9MINT:MINT-6799282OMA:KYDRIAHPANTHER:PTHR11630:SF44PaxDb:Q9LPD9Pfam:PF00493
Pfam:PF12619Pfam:PF14551Pfam:Q9LPD9Pfscan:PS50051PhylomeDB:Q9LPD9PIR:E96508PRIDE:Q9LPD9
PRINTS:PR01657PRINTS:PR01658PRO:PR:Q9LPD9PROSITE:PS00847PROSITE:PS50051ProteinModelPortal:Q9LPD9Proteomes:UP000006548
Reactome:R-ATH-68867Reactome:R-ATH-68949Reactome:R-ATH-68962Reactome:R-ATH-69052Reactome:R-ATH-69300RefSeq:NP_175112.2scanprosite:PS00847
SMART:SM00350SMR:Q9LPD9STRING:3702.AT1G44900.1SUPFAM:SSF50249SUPFAM:SSF52540TAIR:AT1G44900tair10-symbols:ATMCM2
tair10-symbols:MCM2UniGene:At.5390UniProt:Q9LPD9
Coordinates (TAIR10) chr1:+:16970291..16974457
Molecular Weight (calculated) 105589.00 Da
IEP (calculated) 4.76
GRAVY (calculated) -0.57
Length 936 amino acids
Sequence (TAIR10)
(BLAST)
001: MAGENSDNEP SSPASPSSAG FNTDQLPIST SQNSENFSDE EEAAVDTQVI RDEPDEAEDE EEEEGEDLFN DTFMNDYRKM DENDQYESNG IDDSVDDERD
101: LGQAMLDRRA ADADLDAREN RLANRKLPHL LHDNDSDDWN YRPSKRSRTT VPPRGNGGDP DGNPPSSPGV SQPDISMTDQ TDDYQDEDDN DDEAEFEMYR
201: IQGTLREWVM RDEVRRFIAK KFKDFLLTYV KPKNENGDIE YVRLINEMVS ANKCSLEIDY KEFIHVHPNI AIWLADAPQP VLEVMEEVSE KVIFDLHPNY
301: KNIHTKIYVR VTNLPVNDQI RNIRQIHLNT MIRIGGVVTR RSGVFPQLQQ VKYDCNKCGA VLGPFFQNSY SEVKVGSCSE CQSKGPFTVN VEQTIYRNYQ
401: KLTIQESPGT VPAGRLPRHK EVILLNDLID CARPGEEIEV TGIYTNNFDL SLNTKNGFPV FATVVEANYV TKKQDLFSAY KLTQEDKTQI EELSKDPRIV
501: ERIIKSIAPS IYGHEDIKTA LALAMFGGQE KNIKGKHRLR GDINVLLLGD PGTAKSQFLK YVEKTGQRAV YTTGKGASAV GLTAAVHKDP VTREWTLEGG
601: ALVLADRGIC LIDEFDKMND QDRVSIHEAM EQQSISISKA GIVTSLQARC SVIAAANPVG GRYDSSKSFA QNVELTDPIL SRFDILCVVK DVVDPVTDEM
701: LAEFVVNSHF KSQPKGGKME DSDPEDGIQG SSGSTDPEVL PQNLLKKYLT YSKLYVFPKL GELDAKKLET VYANLRRESM NGQGVSIATR HLESMIRMSE
801: AHARMHLRQY VTEEDVNMAI RVLLDSFIST QKFGVQRTLR ESFKRYITYK KDFNSLLLVL LKELVKNALK FEEIISGSNS GLPTIEVKIE ELQTKAKEYD
901: IADLRPFFSS TDFSKAHFEL DHGRGMIKCP KRLITW
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)