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AT1G31360.1
Subcellular Consensus
(Prediction and Experimental)

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SUBAcon:
nucleus 1.000
What is SUBAcon?
What is ASURE?
SUBAcon computations
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
Description (TAIR10) protein_coding : RECQ helicase L2
Curator
Summary (TAIR10)
Encodes a (d)NTP-dependent 3'->5' DNA helicase. This protein can also disrupt D loop structures and may mediate branch migration of Holliday junctions when tested in vitro. The unwinding activity of the enzyme depends on the presence of divalent cations (Mg2+, Mn2+, or Ca2+, but not Zn2+).(d)NTPs are also required with ATP and dATP supporting the greatest amount of DNA unwinding in vitro.
Computational
Description (TAIR10)
RECQ helicase L2 (RECQL2); CONTAINS InterPro DOMAIN/s: DNA/RNA helicase, DEAD/DEAH box type, N-terminal (InterPro:IPR011545), RQC domain (InterPro:IPR018982), DNA helicase, ATP-dependent, RecQ type (InterPro:IPR004589), DNA helicase, ATP-dependent, RecQ type, N-terminal (InterPro:IPR018329), DEAD-like helicase, N-terminal (InterPro:IPR014001), DNA/RNA helicase, C-terminal (InterPro:IPR001650), Helicase, superfamily 1/2, ATP-binding domain (InterPro:IPR014021), Helicase/RNase D C-terminal, HRDC domain (InterPro:IPR002121); BEST Arabidopsis thaliana protein match is: DNA helicase (RECQl4A) (TAIR:AT1G10930.1); Has 32628 Blast hits to 32552 proteins in 2916 species: Archae - 507; Bacteria - 20337; Metazoa - 3383; Fungi - 2416; Plants - 1613; Viruses - 17; Other Eukaryotes - 4355 (source: NCBI BLink).
Protein Annotations
BioCyc:ARA:GQT-1356-MONOMERBioCyc:ARA:GQT-2186-MONOMEREC:3.6.4.12eggNOG:COG0514eggNOG:KOG0351EMBL:AC007654EMBL:AJ404471
EMBL:CP002684EnsemblPlants:AT1G31360EnsemblPlants:AT1G31360.1entrez:840026Gene3D:1.10.10.10Gene3D:3.40.50.300GeneID:840026
Genevisible:Q9FT73GO:GO:0003677GO:GO:0005524GO:GO:0006260GO:GO:0006281GO:GO:0006310GO:GO:0006351
GO:GO:0006355GO:GO:0009378GO:GO:0016592GO:GO:0032508GO:GO:0043138GO:GO:0043140GO:GO:0046872
hmmpanther:PTHR13710hmmpanther:PTHR13710:SF72HOGENOM:HOG000044388InParanoid:Q9FT73IntAct:Q9FT73InterPro:IPR001650InterPro:IPR002121
InterPro:IPR004589InterPro:IPR010997InterPro:IPR011545InterPro:IPR011991InterPro:IPR014001InterPro:IPR018982InterPro:IPR027417
InterPro:IPR032284iPTMnet:Q9FT73KEGG:ath:AT1G31360KO:K10899ncoils:CoilOMA:QKFRPLQPaxDb:Q9FT73
Pfam:PF00270Pfam:PF00271Pfam:PF00570Pfam:PF09382Pfam:PF16124Pfam:Q9FT73Pfscan:PS50967
Pfscan:PS51192Pfscan:PS51194PhylomeDB:Q9FT73PRIDE:Q9FT73PRO:PR:Q9FT73PROSITE:PS50967PROSITE:PS51192
PROSITE:PS51194ProteinModelPortal:Q9FT73Proteomes:UP000006548RefSeq:NP_001077639.1RefSeq:NP_174421.2SMART:SM00487SMART:SM00490
SMART:SM00956SMR:Q9FT73STRING:3702.AT1G31360.1SUPFAM:SSF47819SUPFAM:SSF52540TAIR:AT1G31360tair10-symbols:ATRECQ2
tair10-symbols:MED34tair10-symbols:RECQL2TIGRfam:TIGR00614TIGRFAMs:TIGR00614UniGene:At.40359UniProt:Q9FT73
Coordinates (TAIR10) chr1:+:11232422..11237412
Molecular Weight (calculated) 79373.30 Da
IEP (calculated) 7.49
GRAVY (calculated) -0.39
Length 705 amino acids
Sequence (TAIR10)
(BLAST)
001: MESEAIQEDL QNLDVELKDV QGQISALIEH QDRLYERKSE LKTLLKALAA SGSPVASSGG SSAIENWSET FEWDSRADDV RFNVFGISKY RANQKEIINA
101: IMTGRDVLVI MAAGGGKSLC YQLPAMLRGG TTLVVSPLLS LIQDQVMGLA ALGISAYMLT STSGKENEKF VYKALEKGED DLKILYVTPE KVSKSKRFMS
201: KLEKCHNAGR LSLISIDEAH CCSQWGHDFR PDYKNLSILK TQFPKVPMVA LTATATQKVQ NDLIEMLHIP KCVKFVSSVN RPNLFYSVRE KSAVGKLVVD
301: EIAEFIRESY SNNESGIVYC FSRKECEQIA GDLRERGISA DYYHADMDAN MREKVHMRWS KNKLQVIVGT VAFGMGINKP DVRFVIHHSL SKSMETYYQE
401: SGRAGRDGLP SECILFFRSA DVPRQSSMVF YEYSGLQNLY DIVRYCQSKT KCRRSAFFRH FGEPSQDCNG MCDNCALSSE VKEVDVSDLS KLVVSMVQET
501: QAKDQRVTML QLGDKLRNKH KDLIAELKRD EVEHLVIKLI VDSVLKEEFQ HTPYSTNAYV TMGPLANQLL QGRKTIKMET SSRQTKKLKR SITFSGLELK
601: LDELRKEISA ADGSILPHTV LSTQQIGSIS SQKPVSLQEL ESIIGKLKTE KYGDRILEEV MRHEAVSEQL VEDPTKEETC KSRLRKRAKT QKDVVLVESS
701: GEEEA
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)