AT1G28380.1
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Subcellular Consensus
(Prediction and Experimental) min:  :max.
SUBAcon:plasma membrane 0.932 What is SUBAcon? |
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| Experimental Localisations and PPI |
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SUBAcon links
AGI-AGI relationships |
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| Description (TAIR10) | protein_coding : MAC/Perforin domain-containing protein | ||||||||||||||||||||||||||||||||||||||||||||||||
| Curator Summary (TAIR10) |
This gene is predicted to encode a protein involved in negatively regulating salicylic acid-related defense responses and cell death programs. nsl1 mutants develop necrotic lesions spontaneously and show other features of a defense response, such as higher levels of SA and disease resistance-related transcripts, in the absence of a biotic stimulus. The NSL1 protein is predicted to have a MACPF domain, found in proteins that form a transmembrane pore in mammalian immune responses. NSL1 transcript levels do not appear to change in response to biotic stresses, but are elevated by cycloheximide in seedlings, and by sodium chloride in roots. | ||||||||||||||||||||||||||||||||||||||||||||||||
| Computational Description (TAIR10) |
necrotic spotted lesions 1 (NSL1); CONTAINS InterPro DOMAIN/s: Membrane attack complex component/perforin (MACPF) domain (InterPro:IPR020864); BEST Arabidopsis thaliana protein match is: MAC/Perforin domain-containing protein (TAIR:AT4G24290.2); Has 203 Blast hits to 202 proteins in 18 species: Archae - 0; Bacteria - 0; Metazoa - 1; Fungi - 0; Plants - 202; Viruses - 0; Other Eukaryotes - 0 (source: NCBI BLink). | ||||||||||||||||||||||||||||||||||||||||||||||||
| Protein Annotations |
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| Coordinates (TAIR10) | chr1:+:9963696..9966060 | ||||||||||||||||||||||||||||||||||||||||||||||||
| Molecular Weight (calculated) | 67983.80 Da | ||||||||||||||||||||||||||||||||||||||||||||||||
| IEP (calculated) | 9.13 | ||||||||||||||||||||||||||||||||||||||||||||||||
| GRAVY (calculated) | -0.25 | ||||||||||||||||||||||||||||||||||||||||||||||||
| Length | 612 amino acids | ||||||||||||||||||||||||||||||||||||||||||||||||
| Sequence (TAIR10) (BLAST) |
001: MAFNNFTRLD AHSAAEKAVS VIGLGYDLCS DVRFSACKTT PDGSRLVEID PTRNRDLIFP GGIVVNNVSS SIKCDKGERT RLRSDILSFN QMSEKFNQDM 101: CLSGKIPSGM FNNMFAFSKC WPKDASSVKT LAYDGWFISL YSVEIVRKQL TLRDEVKREV PSSWDSAALA GFIEKYGTHV VVGVTMGGKD VIHVKQMRKS 201: NHEPEEIQKM LKHWGDERFC VDPVESKSPA SVYSGKPKEE NLLQWGLQPF GTSVSSAVVM HTKNEEIMRV CIRRGGVDLG QSHERWLSTV SQAPNVISMC 301: FVPITSLLSG LPGTGFLSHA VNLYLRYKPP IEELHQFLEF QLPRQWAPVY GDLPLGLRRS KQSSPSLQFS LMGPKLYVNT SKVDSGERPV TGLRFFLEGK 401: KGNHLAIHLQ HLSACPPSLH LSHDDTYEPI EEPVEKGYYV PVKWGIFSHV CTYPVQYNGA RSDDTASIVT KAWLEVKGMG MRKVLFLRLG FSLDASAVTR 501: KSCWDNLSTN SRKSGVFSMI STRLSTGLSP NPATTKPQSK IDINSAVYPR GPSPPVKPKL LSLVDTKEVM RGPEEQPGYW VVTGAKLCVE AGKISIKAKY 601: SLLTVISEDS LV |
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| See Also |
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Citation
If you find this resource useful please cite one of the following publications:
Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)
Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)