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AT1G26830.1
Subcellular Consensus
(Prediction and Experimental)

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SUBAcon:
cytosol 0.996
What is SUBAcon?
What is ASURE?
SUBAcon computations
Experimental Localisations and PPI
FP MS/MS PPI
  • PMID:25900983 (2015): Golgi
  • PMID:25900983 (2015): Golgi trans-Golgi network
  • PMID:25900983 (2015): Golgi trans-Golgi network multivesicular body
  • PMID:21166475 (2011): cytosol
SUBAcon links
AGI-AGI relationships
Coexpression PPI
Description (TAIR10) protein_coding : cullin 3
Curator
Summary (TAIR10)
Cullin, putative, similar to Cullin homolog 3 (CUL-3) SP:Q13618, GI:3639052 from (Homo sapiens); contains Pfam profile PF00888: Cullin family. Interacts with other components of E3 ligase complex suggesting it functions in RUB-modification. Forms complexes with BTB domain proteins forming a novel class of E3-based ubiquitin protein-ligase complexes. Mutant is early flowering and has a reduced sensitivity to far-red light. cul3a/cul3b homozygous/heterozygous plants are embryo lethal.
Computational
Description (TAIR10)
cullin 3 (CUL3); CONTAINS InterPro DOMAIN/s: Winged helix-turn-helix transcription repressor DNA-binding (InterPro:IPR011991), Cullin homology (InterPro:IPR016158), Cullin protein, neddylation domain (InterPro:IPR019559), Cullin, N-terminal (InterPro:IPR001373), Cullin repeat-like-containing domain (InterPro:IPR016159); BEST Arabidopsis thaliana protein match is: cullin 3B (TAIR:AT1G69670.1); Has 2310 Blast hits to 2269 proteins in 235 species: Archae - 0; Bacteria - 9; Metazoa - 1034; Fungi - 455; Plants - 372; Viruses - 0; Other Eukaryotes - 440 (source: NCBI BLink).
Protein Annotations
BioGrid:24462DIP:DIP-33568NeggNOG:COG5647eggNOG:KOG2166EMBL:AC005508EMBL:AC006535EMBL:AJ319540
EMBL:AJ344252EMBL:AK230392EMBL:CP002684EnsemblPlants:AT1G26830EnsemblPlants:AT1G26830.1entrez:839226Gene3D:1.10.10.10
GeneID:839226Genevisible:Q9ZVH4GO:GO:0005829GO:GO:0009639GO:GO:0009911GO:GO:0031625GO:GO:0042787
Gramene:AT1G26830.1hmmpanther:PTHR11932hmmpanther:PTHR11932:SF86HOGENOM:HOG000176712InParanoid:Q9ZVH4IntAct:Q9ZVH4InterPro:IPR001373
InterPro:IPR011991InterPro:IPR016158InterPro:IPR016159InterPro:IPR019559KEGG:ath:AT1G26830KO:K03869OMA:HKIRAPR
PaxDb:Q9ZVH4Pfam:PF00888Pfam:PF10557Pfam:Q9ZVH4Pfscan:PS50069PhylomeDB:Q9ZVH4PIR:A86395
PRIDE:Q9ZVH4PRO:PR:Q9ZVH4PROSITE:PS50069ProteinModelPortal:Q9ZVH4Proteomes:UP000006548Reactome:R-ATH-5632684RefSeq:NP_174005.1
SMART:SM00182SMART:SM00884SMR:Q9ZVH4STRING:3702.AT1G26830.1SUPFAM:SSF46785SUPFAM:SSF74788SUPFAM:SSF75632
TAIR:AT1G26830tair10-symbols:ATCUL3tair10-symbols:ATCUL3Atair10-symbols:CUL3tair10-symbols:CUL3AUniGene:At.27879UniProt:Q9ZVH4
Coordinates (TAIR10) chr1:+:9296063..9298374
Molecular Weight (calculated) 85317.90 Da
IEP (calculated) 8.02
GRAVY (calculated) -0.54
Length 732 amino acids
Sequence (TAIR10)
(BLAST)
001: MSNQKKRNFQ IEAFKHRVVV DPKYADKTWQ ILERAIHQIY NQDASGLSFE ELYRNAYNMV LHKFGEKLYT GFIATMTSHL KEKSKLIEAA QGGSFLEELN
101: KKWNEHNKAL EMIRDILMYM DRTYIESTKK THVHPMGLNL WRDNVVHFTK IHTRLLNTLL DLVQKERIGE VIDRGLMRNV IKMFMDLGES VYQEDFEKPF
201: LDASSEFYKV ESQEFIESCD CGDYLKKSEK RLTEEIERVA HYLDAKSEEK ITSVVEKEMI ANHMQRLVHM ENSGLVNMLL NDKYEDLGRM YNLFRRVTNG
301: LVTVRDVMTS HLREMGKQLV TDPEKSKDPV EFVQRLLDER DKYDKIINTA FGNDKTFQNA LNSSFEYFIN LNARSPEFIS LFVDDKLRKG LKGITDVDVE
401: VILDKVMMLF RYLQEKDVFE KYYKQHLAKR LLSGKTVSDD AERSLIVKLK TECGYQFTSK LEGMFTDMKT SEDTMRGFYG SHPELSEGPT LIVQVLTTGS
501: WPTQPAVPCN LPAEVSVLCE KFRSYYLGTH TGRRLSWQTN MGTADIKAIF GKGQKHELNV STFQMCVLML FNNSDRLSYK EIEQATEIPA ADLKRCLQSL
601: ACVKGKNVIK KEPMSKDIGE EDLFVVNDKF TSKFYKVKIG TVVAQKETEP EKQETRQRVE EDRKPQIEAA IVRIMKSRKI LDHNNIIAEV TKQLQPRFLA
701: NPTEIKKRIE SLIERDFLER DSTDRKLYRY LA
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)