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AT1G23080.1
Subcellular Consensus
(Prediction and Experimental)

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SUBAcon:
plasma membrane 1.000
ASURE: plasma membrane
What is SUBAcon?
What is ASURE?
SUBAcon computations
Experimental Localisations and PPI
FP MS/MS PPI
  • PMID:25900983 (2015): Golgi trans-Golgi network
  • PMID:25900983 (2015): Golgi trans-Golgi network early endosome
  • PMID:20843791 (2010): plasma membrane
  • PMID:20374526 (2010): plasma membrane
  • PMID:19334764 (2009): plasma membrane
  • PMID:17317660 (2007): plasma membrane
SUBAcon links
AGI-AGI relationships
Coexpression PPI
Description (TAIR10) protein_coding : Auxin efflux carrier family protein
Curator
Summary (TAIR10)
Encodes a novel component of auxin efflux that is located apically in the basal cell and is involved during embryogenesis in setting up the apical-basal axis in the embryo. It is also involved in pattern specification during root development. In roots, it is expressed at lateral and basal membranes of provascular cells in the meristem and elongation zone, whereas in the columella cells it coincides with the PIN3 domain. Plasma membrane-localized PIN proteins mediate a saturable efflux of auxin. PINs mediate auxin efflux from mammalian and yeast cells without needing additional plant-specific factors. The action of PINs in auxin efflux is distinct from PGPs, rate-limiting, specific to auxins and sensitive to auxin transport inhibitors. PINs are directly involved of in catalyzing cellular auxin efflux.
Computational
Description (TAIR10)
PIN-FORMED 7 (PIN7); FUNCTIONS IN: auxin:hydrogen symporter activity, transporter activity, auxin efflux transmembrane transporter activity; INVOLVED IN: response to cyclopentenone, root development, pattern specification process, auxin polar transport, longitudinal axis specification; LOCATED IN: plasma membrane, membrane; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Auxin efflux carrier, subgroup (InterPro:IPR014024), Auxin efflux carrier (InterPro:IPR004776); BEST Arabidopsis thaliana protein match is: Auxin efflux carrier family protein (TAIR:AT1G70940.1); Has 1748 Blast hits to 1583 proteins in 451 species: Archae - 37; Bacteria - 919; Metazoa - 14; Fungi - 2; Plants - 486; Viruses - 0; Other Eukaryotes - 290 (source: NCBI BLink).
Protein Annotations
BioGrid:24155eggNOG:ENOG410IJ59eggNOG:ENOG410Y9XEEMBL:AC002311EMBL:AF087820EMBL:AY052356EMBL:CP002684
EnsemblPlants:AT1G23080EnsemblPlants:AT1G23080.1entrez:838916ExpressionAtlas:Q940Y5GeneID:838916Genevisible:Q940Y5GO:GO:0005783
GO:GO:0005886GO:GO:0009506GO:GO:0009734GO:GO:0009926GO:GO:0009942GO:GO:0010252GO:GO:0010315
GO:GO:0010329GO:GO:0016020GO:GO:0016021hmmpanther:PTHR31752hmmpanther:PTHR31752:SF14HOGENOM:HOG000238224InParanoid:Q940Y5
IntAct:Q940Y5InterPro:IPR004776InterPro:IPR014024iPTMnet:Q940Y5MINT:MINT-8067764OMA:EESCAMAPaxDb:Q940Y5
Pfam:PF03547Pfam:Q940Y5PhylomeDB:Q940Y5PIR:A86365PRIDE:Q940Y5PRO:PR:Q940Y5ProteinModelPortal:Q940Y5
Proteomes:UP000006548RefSeq:NP_564189.1RefSeq:NP_849700.1STRING:3702.AT1G23080.1TAIR:AT1G23080tair10-symbols:ATPIN7tair10-symbols:PIN7
TCDB:2.A.69.1.3TIGRfam:TIGR00946TIGRFAMs:TIGR00946TMHMM:TMhelixUniGene:At.10543UniProt:Q940Y5
Coordinates (TAIR10) chr1:-:8180768..8183406
Molecular Weight (calculated) 67592.10 Da
IEP (calculated) 7.95
GRAVY (calculated) 0.14
Length 619 amino acids
Sequence (TAIR10)
(BLAST)
001: MITWHDLYTV LTAVIPLYVA MILAYGSVRW WKIFSPDQCS GINRFVAIFA VPLLSFHFIS SNNPYAMNLR FIAADTLQKL IMLTLLIIWA NFTRSGSLEW
101: SITIFSLSTL PNTLVMGIPL LIAMYGEYSG SLMVQIVVLQ CIIWYTLLLF LFEYRGAKIL IMEQFPETGA SIVSFKVESD VVSLDGHDFL ETDAQIGDDG
201: KLHVTVRKSN ASRRSFYGGG GTNMTPRPSN LTGAEIYSLN TTPRGSNFNH SDFYSMMGFP GGRLSNFGPA DMYSVQSSRG PTPRPSNFEE SCAMASSPRF
301: GYYPGGAPGS YPAPNPEFST GNKTGSKAPK ENHHHVGKSN SNDAKELHMF VWGSNGSPVS DRAGLQVDNG ANEQVGKSDQ GGAKEIRMLI SDHTQNGENK
401: AGPMNGDYGG EEESERVKEV PNGLHKLRCN STAELNPKEA IETGETVPVK HMPPASVMTR LILIMVWRKL IRNPNTYSSL IGLIWALVAF RWDVAMPKII
501: QQSISILSDA GLGMAMFSLG LFMALQPKLI ACGNSTATFA MAVRFFTGPA VMAVAAMAIG LRGDLLRVAI VQAALPQGIV PFVFAKEYNV HPAILSTGVI
601: FGMLIALPIT LVYYILLGL
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)