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AT1G20330.1
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
endoplasmic reticulum 1.000
What is SUBAcon?
Predictors External Curations
AmiGO : endoplasmic reticulum 12215504
AmiGO : endoplasmic reticulum 16618929
TAIR : endoplasmic reticulum 16618929
Experimental Localisations and PPI
FP MS/MS PPI
  • PMID:31818904 (2020): mitochondrion
  • PMID:31615849 (2019): plastid plastid thylakoid
  • PMID:31520498 (2020): mitochondrion
  • PMID:28865150 (2017): extracellular region plant-type cell wall
  • PMID:27137770 (2016): plastid plastid stroma
  • PMID:26781341 (2016): plasma membrane
  • PMID:25900983 (2015): plant-type vacuole plant-type vacuole membrane
  • PMID:25900983 (2015): Golgi trans-Golgi network multivesicular body
  • PMID:25900983 (2015): Golgi trans-Golgi network early endosome
  • PMID:25900983 (2015): Golgi trans-Golgi network
  • PMID:25900983 (2015): Golgi Golgi apparatus Golgi membrane
  • PMID:25900983 (2015): Golgi
  • PMID:25641898 (2015): plasma membrane
  • PMID:22923678 (2012): endoplasmic reticulum
  • PMID:22550958 (2012): plastid
  • PMID:22430844 (2012): Golgi
  • PMID:22215637 (2012): plasma membrane
  • PMID:21533090 (2011): extracellular region plant-type cell wall
  • PMID:19334764 (2009): plasma membrane
  • PMID:16618929 (2006): endoplasmic reticulum
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : sterol methyltransferase 2
Curator
Summary (TAIR10)
Encodes a sterol-C24-methyltransferases involved in sterol biosynthesis. Mutants display altered sterol composition, serrated petals and sepals and altered cotyledon vascular patterning as well as ectopic endoreduplication. This suggests that suppression of endoreduplication is important for petal morphogenesis and that normal sterol composition is required for this suppression.
Computational
Description (TAIR10)
sterol methyltransferase 2 (SMT2); FUNCTIONS IN: S-adenosylmethionine-dependent methyltransferase activity; INVOLVED IN: xylem and phloem pattern formation, negative regulation of DNA endoreduplication, multidimensional cell growth, sterol biosynthetic process, pattern specification process; LOCATED IN: endoplasmic reticulum; EXPRESSED IN: 30 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Sterol methyltransferase C-terminal (InterPro:IPR013705), Methyltransferase type 11 (InterPro:IPR013216); BEST Arabidopsis thaliana protein match is: sterol methyltransferase 3 (TAIR:AT1G76090.1); Has 13231 Blast hits to 13223 proteins in 2296 species: Archae - 440; Bacteria - 9200; Metazoa - 162; Fungi - 455; Plants - 664; Viruses - 0; Other Eukaryotes - 2310 (source: NCBI BLink).
Protein Annotations
BioCyc:MetaCyc:AT1G20330-MONOMERBioGrid:23860EC:2.1.1.143eggNOG:ENOG410XP5G
eggNOG:KOG1269EMBL:AC026234EMBL:AF332417EMBL:AY046042
EMBL:AY086699EMBL:AY113961EMBL:AY128389EMBL:BT000750
EMBL:BT002093EMBL:CP002684EMBL:X89867EnsemblPlants:AT1G20330
EnsemblPlants:AT1G20330.1entrez:838621Gene3D:3.40.50.150GeneID:838621
Genevisible:Q39227GO:GO:0005783GO:GO:0005794GO:GO:0007389
GO:GO:0008757GO:GO:0009825GO:GO:0010051GO:GO:0016126
GO:GO:0030797GO:GO:0032876Gramene:AT1G20330.1gramene_plant_reactome:1119370
gramene_plant_reactome:6876503hmmpanther:PTHR10108hmmpanther:PTHR10108:SF858HOGENOM:HOG000171097
InParanoid:Q39227InterPro:IPR013216InterPro:IPR013705InterPro:IPR029063
InterPro:IPR030384iPTMnet:Q39227KEGG:ath:AT1G20330KO:K08242
MINT:MINT-8063517OMA:KMGRVAYPaxDb:Q39227Pfam:PF08241
Pfam:PF08498Pfam:Q39227Pfscan:PS51685PhylomeDB:Q39227
PIR:S63686PRIDE:Q39227PRO:PR:Q39227PROSITE:PS51685
ProteinModelPortal:Q39227Proteomes:UP000006548RefSeq:NP_173458.1SMR:Q39227
STRING:3702.AT1G20330.1SUPFAM:SSF53335SwissPalm:Q39227TAIR:AT1G20330
tair10-symbols:CVP1tair10-symbols:FRL1tair10-symbols:SMT2TMHMM:TMhelix
UniGene:At.186UniGene:At.71890UniPathway:UPA00766UniProt:Q39227
Coordinates (TAIR10) chr1:-:7038968..7040053
Molecular Weight (calculated) 40452.40 Da
IEP (calculated) 6.02
GRAVY (calculated) -0.23
Length 361 amino acids
Sequence (TAIR10)
(BLAST)
001: MDSLTLFFTG ALVAVGIYWF LCVLGPAERK GKRAVDLSGG SISAEKVQDN YKQYWSFFRR PKEIETAEKV PDFVDTFYNL VTDIYEWGWG QSFHFSPSIP
101: GKSHKDATRL HEEMAVDLIQ VKPGQKILDV GCGVGGPMRA IASHSRANVV GITINEYQVN RARLHNKKAG LDALCEVVCG NFLQMPFDDN SFDGAYSIEA
201: TCHAPKLEEV YAEIYRVLKP GSMYVSYEWV TTEKFKAEDD EHVEVIQGIE RGDALPGLRA YVDIAETAKK VGFEIVKEKD LASPPAEPWW TRLKMGRLAY
301: WRNHIVVQIL SAVGVAPKGT VDVHEMLFKT ADYLTRGGET GIFSPMHMIL CRKPESPEES S
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)