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AT1G20330.1
Subcellular Consensus
(Prediction and Experimental)

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SUBAcon:
endoplasmic reticulum 1.000
What is SUBAcon?
What is ASURE?
SUBAcon computations
Predictors External Curations
AmiGO : endoplasmic reticulum 12215504
AmiGO : endoplasmic reticulum 16618929
TAIR : endoplasmic reticulum 16618929
Experimental Localisations and PPI
FP MS/MS PPI
  • PMID:26781341 (2016): plasma membrane
  • PMID:25900983 (2015): plant-type vacuole plant-type vacuole membrane
  • PMID:25900983 (2015): Golgi trans-Golgi network multivesicular body
  • PMID:25900983 (2015): Golgi trans-Golgi network early endosome
  • PMID:25900983 (2015): Golgi trans-Golgi network
  • PMID:25900983 (2015): Golgi Golgi apparatus Golgi membrane
  • PMID:25900983 (2015): Golgi
  • PMID:25641898 (2015): plasma membrane
  • PMID:22923678 (2012): endoplasmic reticulum
  • PMID:22430844 (2012): Golgi
  • PMID:22215637 (2012): plasma membrane
  • PMID:19334764 (2009): plasma membrane
  • PMID:16618929 (2006): endoplasmic reticulum
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : sterol methyltransferase 2
Curator
Summary (TAIR10)
Encodes a sterol-C24-methyltransferases involved in sterol biosynthesis. Mutants display altered sterol composition, serrated petals and sepals and altered cotyledon vascular patterning as well as ectopic endoreduplication. This suggests that suppression of endoreduplication is important for petal morphogenesis and that normal sterol composition is required for this suppression.
Computational
Description (TAIR10)
sterol methyltransferase 2 (SMT2); FUNCTIONS IN: S-adenosylmethionine-dependent methyltransferase activity; INVOLVED IN: xylem and phloem pattern formation, negative regulation of DNA endoreduplication, multidimensional cell growth, sterol biosynthetic process, pattern specification process; LOCATED IN: endoplasmic reticulum; EXPRESSED IN: 30 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Sterol methyltransferase C-terminal (InterPro:IPR013705), Methyltransferase type 11 (InterPro:IPR013216); BEST Arabidopsis thaliana protein match is: sterol methyltransferase 3 (TAIR:AT1G76090.1); Has 13231 Blast hits to 13223 proteins in 2296 species: Archae - 440; Bacteria - 9200; Metazoa - 162; Fungi - 455; Plants - 664; Viruses - 0; Other Eukaryotes - 2310 (source: NCBI BLink).
Protein Annotations
BioCyc:MetaCyc:AT1G20330-MONOMERBioGrid:23860EC:2.1.1.143eggNOG:ENOG410XP5GeggNOG:KOG1269EMBL:AC026234EMBL:AF332417
EMBL:AY046042EMBL:AY086699EMBL:AY113961EMBL:AY128389EMBL:BT000750EMBL:BT002093EMBL:CP002684
EMBL:X89867EnsemblPlants:AT1G20330EnsemblPlants:AT1G20330.1entrez:838621Gene3D:3.40.50.150GeneID:838621Genevisible:Q39227
GO:GO:0005783GO:GO:0005794GO:GO:0007389GO:GO:0008757GO:GO:0009825GO:GO:0010051GO:GO:0016126
GO:GO:0030797GO:GO:0032876Gramene:AT1G20330.1gramene_plant_reactome:1119370gramene_plant_reactome:6876503hmmpanther:PTHR10108hmmpanther:PTHR10108:SF858
HOGENOM:HOG000171097InParanoid:Q39227InterPro:IPR013216InterPro:IPR013705InterPro:IPR029063InterPro:IPR030384iPTMnet:Q39227
KEGG:ath:AT1G20330KO:K08242MINT:MINT-8063517OMA:KMGRVAYPaxDb:Q39227Pfam:PF08241Pfam:PF08498
Pfam:Q39227Pfscan:PS51685PhylomeDB:Q39227PIR:S63686PRIDE:Q39227PRO:PR:Q39227PROSITE:PS51685
ProteinModelPortal:Q39227Proteomes:UP000006548RefSeq:NP_173458.1SMR:Q39227STRING:3702.AT1G20330.1SUPFAM:SSF53335SwissPalm:Q39227
TAIR:AT1G20330tair10-symbols:CVP1tair10-symbols:FRL1tair10-symbols:SMT2TMHMM:TMhelixUniGene:At.186UniGene:At.71890
UniPathway:UPA00766UniProt:Q39227
Coordinates (TAIR10) chr1:-:7038968..7040053
Molecular Weight (calculated) 40452.40 Da
IEP (calculated) 6.02
GRAVY (calculated) -0.23
Length 361 amino acids
Sequence (TAIR10)
(BLAST)
001: MDSLTLFFTG ALVAVGIYWF LCVLGPAERK GKRAVDLSGG SISAEKVQDN YKQYWSFFRR PKEIETAEKV PDFVDTFYNL VTDIYEWGWG QSFHFSPSIP
101: GKSHKDATRL HEEMAVDLIQ VKPGQKILDV GCGVGGPMRA IASHSRANVV GITINEYQVN RARLHNKKAG LDALCEVVCG NFLQMPFDDN SFDGAYSIEA
201: TCHAPKLEEV YAEIYRVLKP GSMYVSYEWV TTEKFKAEDD EHVEVIQGIE RGDALPGLRA YVDIAETAKK VGFEIVKEKD LASPPAEPWW TRLKMGRLAY
301: WRNHIVVQIL SAVGVAPKGT VDVHEMLFKT ADYLTRGGET GIFSPMHMIL CRKPESPEES S
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)