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AT1G18450.1
Subcellular Consensus
(Prediction and Experimental)

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SUBAcon:
nucleus 1.000
ASURE: nucleus
What is SUBAcon?
What is ASURE?
SUBAcon computations
Experimental Localisations and PPI
FP MS/MS PPI
  • PMID:25900983 (2015): plant-type vacuole plant-type vacuole membrane
  • PMID:25900983 (2015): Golgi trans-Golgi network multivesicular body
  • PMID:25900983 (2015): Golgi trans-Golgi network early endosome
  • PMID:25900983 (2015): Golgi trans-Golgi network
  • PMID:25900983 (2015): Golgi Golgi apparatus Golgi membrane
  • PMID:25900983 (2015): Golgi
  • PMID:24134884 (2013): cytoskeleton microtubules
  • PMID:23396599 (2013): nucleus nuclear envelope nuclear inner membrane
  • PMID:21433285 (2011): plasma membrane
  • PMID:15496452 (2005): nucleus
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : actin-related protein 4
Curator
Summary (TAIR10)
Encodes a gene similar to actin-related proteins in other organisms. Member of nuclear ARP family of genes. Component of chromatin remodeling complexes, involved in chromatin-mediated gene regulation. Phenotype of the arp4-1 mutant allele revealed partial sterility due to defects in anther development. Targeting the distinct, 3' UTR of AtARP4 transcripts with RNA interference caused a drastic reduction in the level of AtARP4 protein expression, and resulted in strong pleiotropic phenotypes such as altered organization of plant organs, early flowering, delayed flower senescence and high levels of sterility. Western blot analysis and immunolabelling demonstrated a clear correlation between reductions in the level of AtARP4 expression and severity of the phenotypes.
Computational
Description (TAIR10)
actin-related protein 4 (ARP4); FUNCTIONS IN: structural constituent of cytoskeleton; INVOLVED IN: long-day photoperiodism, flowering, chromatin organization, pollen sperm cell differentiation; LOCATED IN: nucleolus, nucleus; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Actin/actin-like (InterPro:IPR004000); BEST Arabidopsis thaliana protein match is: actin-11 (TAIR:AT3G12110.1); Has 13669 Blast hits to 13362 proteins in 2792 species: Archae - 2; Bacteria - 480; Metazoa - 5593; Fungi - 3430; Plants - 1457; Viruses - 2; Other Eukaryotes - 2705 (source: NCBI BLink).
Protein Annotations
BioGrid:23664eggNOG:COG5277eggNOG:KOG0679EMBL:AC013354EMBL:AF507912EMBL:AK228098EMBL:AY087788
EMBL:BK000422EMBL:BT006474EMBL:CP002684EnsemblPlants:AT1G18450EnsemblPlants:AT1G18450.1entrez:838425GeneID:838425
Genevisible:Q84M92GO:GO:0005200GO:GO:0005634GO:GO:0005730GO:GO:0005737GO:GO:0006281GO:GO:0006325
GO:GO:0006338GO:GO:0006355GO:GO:0031011GO:GO:0035267GO:GO:0048235GO:GO:0048574Gramene:AT1G18450.1
hmmpanther:PTHR11937hmmpanther:PTHR11937:SF235HOGENOM:HOG000233340InParanoid:Q84M92InterPro:IPR004000InterPro:IPR027667iPTMnet:Q84M92
KEGG:ath:AT1G18450KO:K11340OMA:WDIVENIPANTHER:PTHR11937PANTHER:PTHR11937:SF235PaxDb:Q84M92Pfam:PF00022
Pfam:Q84M92PhylomeDB:Q84M92PIR:C86318PRIDE:Q84M92PRO:PR:Q84M92ProteinModelPortal:Q84M92Proteomes:UP000006548
RefSeq:NP_564051.1SMART:SM00268SMR:Q84M92STRING:3702.AT1G18450.1SUPFAM:SSF53067TAIR:AT1G18450tair10-symbols:ARP4
tair10-symbols:ATARP4UniGene:At.16658UniProt:Q84M92
Coordinates (TAIR10) chr1:+:6348199..6351766
Molecular Weight (calculated) 48939.30 Da
IEP (calculated) 4.99
GRAVY (calculated) -0.36
Length 441 amino acids
Sequence (TAIR10)
(BLAST)
001: MYGGDEVSAI VVDLGSHTCK AGYAGEDAPK AVFPSVIGAV DGVEAMDVDV DSTKTNSNSE DSKTESEKEK SKRKLYVGSQ AMSYRRDHME VLSPIKDGIV
101: SDWDLVDNIW EHAFKSCLMI DPTEHPMLLA EPPLNTQQQR EKAAELMFEK YKVPALFMAK NPVLTSFATG RATSLVVDCG GGSTTISPVH DGYVLQKAVV
201: SSPLGGEFLT DCLLKSLESK GIKIRPRYSF KRKEVRAGEF QVEDVDIPDT TESYKLFCQR MIVGDIKDSI CRVPDTPYDD KSYSNIPTTS YELPDGQTLE
301: IGADRFKVPD VMFNPSIVQT IPGMEKYAEM IPSVRGLPHM VMESINKCDV DIRRELYSSI LLAGGTSSMQ QLKERLEKDL IEESPHSARV KVLASGNTTE
401: RRFSVWIGGS ILASLGSFQQ MWFSKSEYEE HGASYIQRKC P
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)