AT1G11400.1
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Subcellular Consensus
(Prediction and Experimental) min:  :max.
SUBAcon:cytosol 0.500 nucleus 0.500 ASURE: cytosol,nucleus What is SUBAcon? |
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| Experimental Localisations and PPI |
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SUBAcon links
AGI-AGI relationships |
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| Description (TAIR10) | protein_coding : partner of Y14-MAGO | ||||||||||||||||||||||||||||||||||||||||||||
| Curator Summary (TAIR10) |
The PYM gene encodes a protein capable of interacting with MAGO, and Y14, whose orthologs form part of the exon junction complex in animal cells. In vitro binding assays indicate that PYM can bind to MAGO and Y14 either individually, or when they are together. But, MAGO-Y14-PYM ternary complexes are difficult to detect in vivo in Arabidopsis based on pull-down experiments. However there is some evidence for a weak association in Arabidopsis flowers. PYM appears primarily cytoplasmic, but it also seems to into the nucleus at times. Its nuclear localization signal has not been rigorously defined, but there is evidence for a nuclear export signal between amino acids 171-205 in the C-terminus. | ||||||||||||||||||||||||||||||||||||||||||||
| Computational Description (TAIR10) |
partner of Y14-MAGO (PYM); CONTAINS InterPro DOMAIN/s: Exon junction complex, Pym (InterPro:IPR015362); Has 344 Blast hits to 344 proteins in 136 species: Archae - 0; Bacteria - 3; Metazoa - 157; Fungi - 114; Plants - 46; Viruses - 0; Other Eukaryotes - 24 (source: NCBI BLink). | ||||||||||||||||||||||||||||||||||||||||||||
| Protein Annotations |
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| Coordinates (TAIR10) | chr1:+:3838777..3839978 | ||||||||||||||||||||||||||||||||||||||||||||
| Molecular Weight (calculated) | 22589.70 Da | ||||||||||||||||||||||||||||||||||||||||||||
| IEP (calculated) | 10.13 | ||||||||||||||||||||||||||||||||||||||||||||
| GRAVY (calculated) | -1.22 | ||||||||||||||||||||||||||||||||||||||||||||
| Length | 204 amino acids | ||||||||||||||||||||||||||||||||||||||||||||
| Sequence (TAIR10) (BLAST) |
001: MGSRSGEQGK RMAELSKNLK EGERILEPTR RPDGTLRKPI RIRPGYTPED EVVKYQSKGS LMKKEMASQG PPGYEPDPAP KPKTKAAKRN ERKKEKRLQA 101: TAEKANSSED GSASNGSQSV NVLASEMEAL DVSSNNDVCG GAPNPGTTGE DVEKRIRALK KKIRLTEAQQ QKTASRDLNP EQLEKFSKLE EWRQELKALE 201: DKAA |
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| See Also |
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Citation
If you find this resource useful please cite one of the following publications:
Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)
Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)