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AT1G08860.1
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
cytosol 0.887
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : Calcium-dependent phospholipid-binding Copine family protein
Curator
Summary (TAIR10)
Encodes a copine-like protein, which is a member of a newly identified class of calcium-dependent, phospholipid binding proteins that are present in a wide range of organisms. Overexpression of this gene suppresses bon1-1 phenotypes. Double mutant analyses with bon1-1 suggest that BON1 and BON3 have overlapping functions in maintaining cellular homeostasis and inhibiting cell death.
Computational
Description (TAIR10)
BONZAI 3 (BON3); FUNCTIONS IN: calcium-dependent phospholipid binding; INVOLVED IN: N-terminal protein myristoylation, cellular homeostasis, positive regulation of cellular defense response, negative regulation of cell death; EXPRESSED IN: sperm cell, male gametophyte, flower, pollen tube; EXPRESSED DURING: L mature pollen stage, M germinated pollen stage, 4 anthesis, petal differentiation and expansion stage; CONTAINS InterPro DOMAIN/s: C2 membrane targeting protein (InterPro:IPR018029), C2 calcium/lipid-binding domain, CaLB (InterPro:IPR008973), Copine (InterPro:IPR010734), C2 calcium-dependent membrane targeting (InterPro:IPR000008), von Willebrand factor, type A (InterPro:IPR002035); BEST Arabidopsis thaliana protein match is: DCD (Development and Cell Death) domain protein (TAIR:AT5G61910.4); Has 1559 Blast hits to 1479 proteins in 107 species: Archae - 0; Bacteria - 0; Metazoa - 903; Fungi - 12; Plants - 319; Viruses - 0; Other Eukaryotes - 325 (source: NCBI BLink).
Protein Annotations
BioGrid:22649eggNOG:ENOG410XPC8eggNOG:KOG1327EMBL:AC000106
EMBL:AY741136EMBL:CP002684EMBL:DQ459165EnsemblPlants:AT1G08860
EnsemblPlants:AT1G08860.1entrez:837408Gene3D:2.60.40.150GeneID:837408
Genevisible:Q5XQC7GO:GO:0005544GO:GO:0005886GO:GO:0006952
GO:GO:0060548GO:GO:0090332Gramene:AT1G08860.1hmmpanther:PTHR10857
hmmpanther:PTHR10857:SF26HOGENOM:HOG000220898InParanoid:Q5XQC7IntAct:Q5XQC7
InterPro:IPR000008InterPro:IPR002035InterPro:IPR010734InterPro:IPR031116
KEGG:ath:AT1G08860OMA:FLGEANCPANTHER:PTHR10857:SF26PaxDb:Q5XQC7
Pfam:PF00168Pfam:PF07002Pfam:Q5XQC7Pfscan:PS50004
Pfscan:PS50234PhylomeDB:Q5XQC7PIR:D86220PRIDE:Q5XQC7
PRO:PR:Q5XQC7PROSITE:PS50004PROSITE:PS50234ProteinModelPortal:Q5XQC7
Proteomes:UP000006548Reactome:R-ATH-1483206RefSeq:NP_172362.3SMART:SM00239
SMART:SM00327SMR:Q5XQC7STRING:3702.AT1G08860.1SUPFAM:SSF49562
SUPFAM:SSF53300TAIR:AT1G08860tair10-symbols:BON3UniGene:At.51165
UniProt:Q5XQC7
Coordinates (TAIR10) chr1:+:2842153..2846138
Molecular Weight (calculated) 64205.70 Da
IEP (calculated) 5.90
GRAVY (calculated) -0.10
Length 584 amino acids
Sequence (TAIR10)
(BLAST)
001: MGGCLSGDVK GGKQAIGGVQ QRPTSSTIAN NAAHNDAVDF FFRSRGQYPL FSQIELTLSA SNLLDCDITS KSDPMAVMYL RKKDGRLEEI GRTEVILNNL
101: NPKWIEKITV SFQFEAVQTL VFHVYDVDTR YHNVPVKTLK LKDQDFLGEG TCVLSEIMTR QNRTLTLTLT GNVRAGVNRN LGTLSIQAEE TVASKTVAEI
201: NFRCVNLDNK DLFSKSDPFL RISRVVETSA AVPICRTEVV DNNLNPMWRP VCLTMQQFGS KDTPLVIECL DFNTSGNHEL IGKTEKSVAE LERLCLQKEA
301: ANFVYPSLSH GRNKVLKGQL IVDRYVEKVQ YSFLDYISSG FELNFMVAVD FTASNGDPRT PSSLHYIDPS GRLNSYQQAI MEVGEVIQFY DSDKRFPAWG
401: FGGRTSDGSV SHAFNLNGAS YGDEVVGVEG IMVAYASALR NVSLAGPTLF SNVVDKAAHT ASQSLSQNSP KYFVLLIITD GVLTDMAGTV DALVRASDLP
501: LSVLIVGVGN TDFKQMEMLD ADNGRRLESS TGRIATRDIV QFVPMKDIHS GLVSVVQALL EELPGQFLTY VRSRKINPIG APAI
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)