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AT1G04220.1
Subcellular Consensus
(Prediction and Experimental)

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SUBAcon:
plasma membrane 0.435
vacuole 0.428
What is SUBAcon?
What is ASURE?
SUBAcon computations
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : 3-ketoacyl-CoA synthase 2
Curator
Summary (TAIR10)
Encodes KCS2, a member of the 3-ketoacyl-CoA synthase family involved in the biosynthesis of VLCFA (very long chain fatty acids).
Computational
Description (TAIR10)
3-ketoacyl-CoA synthase 2 (KCS2); FUNCTIONS IN: fatty acid elongase activity; INVOLVED IN: response to wounding, response to osmotic stress, suberin biosynthetic process; LOCATED IN: membrane; EXPRESSED IN: 17 plant structures; EXPRESSED DURING: 6 growth stages; CONTAINS InterPro DOMAIN/s: Thiolase-like (InterPro:IPR016039), Very-long-chain 3-ketoacyl-CoA synthase (InterPro:IPR012392), 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C-terminal (InterPro:IPR013747), FAE1/Type III polyketide synthase-like protein (InterPro:IPR013601), Thiolase-like, subgroup (InterPro:IPR016038); BEST Arabidopsis thaliana protein match is: 3-ketoacyl-CoA synthase 20 (TAIR:AT5G43760.1); Has 5259 Blast hits to 5241 proteins in 1449 species: Archae - 0; Bacteria - 2406; Metazoa - 0; Fungi - 4; Plants - 2679; Viruses - 0; Other Eukaryotes - 170 (source: NCBI BLink).
Protein Annotations
BioCyc:ARA:AT1G04220-MONOMERBioGrid:24813ChEMBL:CHEMBL2242736EC:2.3.1.199eggNOG:ENOG410IHMWeggNOG:ENOG410Y5VHEMBL:AC002411
EMBL:AK222101EMBL:AY074518EMBL:BT015917EMBL:CP002684EnsemblPlants:AT1G04220EnsemblPlants:AT1G04220.1entrez:839578
Gene3D:3.40.47.10GeneID:839578Genevisible:Q5XEP9GO:GO:0006633GO:GO:0006970GO:GO:0009611GO:GO:0009922
GO:GO:0010345GO:GO:0016021Gramene:AT1G04220.1gramene_pathway:2.3.1.-gramene_pathway:PWY-5080hmmpanther:PTHR31561hmmpanther:PTHR31561:SF25
HOGENOM:HOG000238893InParanoid:Q5XEP9InterPro:IPR012392InterPro:IPR013601InterPro:IPR013747InterPro:IPR016039KEGG:00061+2.3.1.180
KEGG:00062+2.3.1.199KEGG:ath:AT1G04220KO:K15397MINT:MINT-8063327OMA:FTTRPRKPANTHER:PTHR31561PaxDb:Q5XEP9
Pfam:PF08392Pfam:PF08541Pfam:Q5XEP9PhylomeDB:Q5XEP9PIR:T00951PIRSF:PIRSF036417PRIDE:Q5XEP9
PRO:PR:Q5XEP9ProteinModelPortal:Q5XEP9Proteomes:UP000006548RefSeq:NP_171918.1SMR:Q5XEP9STRING:3702.AT1G04220.1SUPFAM:SSF53901
TAIR:AT1G04220tair10-symbols:KCS2TMHMM:TMhelixUniGene:At.20865UniGene:At.48152UniPathway:UPA00094UniProt:Q5XEP9
Coordinates (TAIR10) chr1:-:1119853..1122483
Molecular Weight (calculated) 59531.20 Da
IEP (calculated) 9.58
GRAVY (calculated) -0.11
Length 528 amino acids
Sequence (TAIR10)
(BLAST)
001: MNENHIQSDH MNNTIHVTNK KLPNFLLSVR LKYVKLGYHY LISNAVYILI LPVGLLAATS SSFSLTDLTL LYNHLLKFHF LSSTLFAALL IFLTTLYFTT
101: RPRRIFLLDF ACYKPDSSLI CTRETFMDRS QRVGIFTEDN LAFQQKILER SGLGQKTYFP EALLRVPPNP CMSEARKEAE TVMFGAIDAV LEKTGVNPKD
201: IGILVVNCSL FNPTPSLSAM IVNKYKLRGN VLSYNLGGMG CSAGLISIDL AKQLLQVQPN SYALVVSTEN ITLNWYLGND RSMLLSNCIF RMGGAAVLLS
301: NRSSDRCRSK YQLIHTVRTH KGSDDNAFNC VYQREDNDDN KQIGVSLSKN LMAIAGEALK TNITTLGPLV LPMSEQLLFF ATLVARKVFN VKKIKPYIPD
401: FKLAFEHFCI HAGGRAVLDE IEKNLDLSEW HMEPSRMTLN RFGNTSSSSL WYELAYSEAK GRIKRGDRTW QIAFGSGFKC NSAVWRALRT IDPSKEKKKK
501: TNPWIDEIHE FPVPVPRTSP VTSSSESR
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)