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AT1G04020.1
Subcellular Consensus
(Prediction and Experimental)

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SUBAcon:
nucleus 1.000
ASURE: nucleus
What is SUBAcon?
What is ASURE?
SUBAcon computations
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : breast cancer associated RING 1
Curator
Summary (TAIR10)
Encodes a protein containing two tandem BRCA1 C-Terminal (BRCT) domains, which function in phosphorylation-dependent protein–protein interactions.Loss of function mutations cause defects in meristem organization due to failure to repress WUS. BARD1 binds to WUS promoter and over expression of BARD reduces the extent of WUS expression.
Computational
Description (TAIR10)
breast cancer associated RING 1 (BARD1); FUNCTIONS IN: transcription coactivator activity, DNA binding; INVOLVED IN: DNA repair, regulation of meristem structural organization, leaf development; LOCATED IN: intracellular; EXPRESSED IN: 21 plant structures; EXPRESSED DURING: 12 growth stages; CONTAINS InterPro DOMAIN/s: Zinc finger, RING-type, conserved site (InterPro:IPR017907), Zinc finger, RING-type (InterPro:IPR001841), Zinc finger, PHD-type (InterPro:IPR001965), BRCT (InterPro:IPR001357); BEST Arabidopsis thaliana protein match is: breast cancer susceptibility1 (TAIR:AT4G21070.1); Has 5889 Blast hits to 5527 proteins in 313 species: Archae - 0; Bacteria - 10; Metazoa - 4435; Fungi - 374; Plants - 570; Viruses - 11; Other Eukaryotes - 489 (source: NCBI BLink).
Protein Annotations
eggNOG:ENOG410ITQ6eggNOG:ENOG4111WR7EMBL:AC003027EMBL:CP002684EMBL:EU817406EMBL:EU817407EnsemblPlants:AT1G04020
EnsemblPlants:AT1G04020.1entrez:839329ExpressionAtlas:F4I443Gene3D:3.30.40.10Gene3D:3.40.50.10190GeneID:839329Genevisible:F4I443
GO:GO:0000724GO:GO:0003677GO:GO:0004842GO:GO:0005634GO:GO:0005886GO:GO:0006281GO:GO:0006351
GO:GO:0008270GO:GO:0009934GO:GO:0010078GO:GO:0010492GO:GO:0016567GO:GO:0031436GO:GO:0035066
GO:GO:0035067GO:GO:0042127GO:GO:0045717GO:GO:0045892GO:GO:0045944GO:GO:0048366GO:GO:0065004
GO:GO:0070531GO:GO:0071158GO:GO:0080182hmmpanther:PTHR13763HOGENOM:HOG000083707InParanoid:F4I443InterPro:IPR001357
InterPro:IPR001841InterPro:IPR001965InterPro:IPR013083InterPro:IPR017907InterPro:IPR031099KEGG:00220+6.3.2.-KEGG:00261+6.3.2.-
KEGG:00380+6.3.2.-KEGG:ath:AT1G04020KO:K10683OMA:MNPWVLHPANTHER:PTHR13763PaxDb:F4I443Pfam:F4I443
Pfam:PF00533Pfam:PF13771Pfam:PF13920Pfscan:PS50089Pfscan:PS50172PIR:D86171PRIDE:F4I443
PRO:PR:F4I443PROSITE:PS00518PROSITE:PS50089PROSITE:PS50172ProteinModelPortal:F4I443Proteomes:UP000006548Reactome:R-ATH-3108214
RefSeq:NP_171898.2scanprosite:PS00518SMART:SM00184SMART:SM00249SMART:SM00292SMR:F4I443STRING:3702.AT1G04020.1
SUPFAM:SSF52113SUPFAM:SSF57850TAIR:AT1G04020tair10-symbols:ATBARD1tair10-symbols:BARD1tair10-symbols:ROW1UniGene:At.49850
UniProt:F4I443
Coordinates (TAIR10) chr1:+:1036610..1040045
Molecular Weight (calculated) 79694.10 Da
IEP (calculated) 6.96
GRAVY (calculated) -0.59
Length 714 amino acids
Sequence (TAIR10)
(BLAST)
001: MAEFTNMLMN PWVLHLQKLE LELKCPLCLK LLNRPVLLPC DHVFCDSCVH KSSQVESGCP VCKSKHPKKA RRDLRFMESV ISIYKSLNAA VSVHLPQLQI
101: PNDCNYKNDA LNNSNSPKHG ESEDSEMTDK DVSKRSGGTD SSSRDGSPLP TSEESDPRPK HQDWTEKQLS DHLLLYEFES EYDAANHTPE SYTEQAAKNV
201: RDITASEQPS NAARKRICGD SFIQESSPNP KTQDPTLLRL MESLRSDDPT DYVKAQNHQQ LPKSHTEQDS KRKRDITASD AMENHLKVPK RENNLMQKSA
301: DIDCNGKCSA NSDDQLSEKI SKALEQTSSN ITICGFCQSA RVSEATGEML HYSRGRPVDG DDIFRSNVIH VHSACIEWAP QVYYEGDTVK NLKAELARGM
401: KIKCTKCSLK GAALGCFVKS CRRSYHVPCA REISRCRWDY EDFLLLCPAH SSVKFPNEKS GHRVSRAEPL PKINPAELCS LEQTPAFTKE LVLCGSALSK
501: SDKKLMESLA VRFNATISRY WNPSVTHVIA STDEKGACTR TLKVLMGILN GKWIINAAWM KASLKASQPV DEEPFEIQID TQGCQDGPKT ARLRAETNKP
601: KLFEGLKFYF FGDFYKGYKE DLQNLVKVAG GTILNTEDEL GAESSNNVND QRSSSIVVYN IDPPHGCALG EEVTIIWQRA NDAEALASQT GSRLVGHTWV
701: LESIAGYKLH PVIG
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)