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AT1G03090.1
Subcellular Consensus
(Prediction and Experimental)

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SUBAcon:
mitochondrion 1.000
ASURE: mitochondrion
What is SUBAcon?
What is ASURE?
SUBAcon computations
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : methylcrotonyl-CoA carboxylase alpha chain, mitochondrial / 3-methylcrotonyl-CoA carboxylase 1 (MCCA)
Curator
Summary (TAIR10)
MCCA is the biotinylated subunit of the dimer MCCase, which is involved in leucine degradation. Both subunits are nuclear coded and the active enzyme is located in the mitochondrion.
Computational
Description (TAIR10)
MCCA; FUNCTIONS IN: cobalt ion binding, methylcrotonoyl-CoA carboxylase activity; INVOLVED IN: leucine catabolic process; LOCATED IN: mitochondrion, cytosolic ribosome; EXPRESSED IN: 26 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Single hybrid motif (InterPro:IPR011053), Biotin/lipoyl attachment (InterPro:IPR000089), Carbamoyl phosphate synthase, large subunit, N-terminal (InterPro:IPR005481), Carbamoyl phosphate synthetase, large subunit, ATP-binding (InterPro:IPR005479), PreATP-grasp-like fold (InterPro:IPR016185), Biotin-binding site (InterPro:IPR001882), Biotin carboxylation domain (InterPro:IPR011764), Biotin carboxylase, C-terminal (InterPro:IPR005482), ATP-grasp fold (InterPro:IPR011761), ATP-grasp fold, subdomain 2 (InterPro:IPR013816), Rudiment single hybrid motif (InterPro:IPR011054), Pre-ATP-grasp fold (InterPro:IPR013817); BEST Arabidopsis thaliana protein match is: acetyl Co-enzyme a carboxylase biotin carboxylase subunit (TAIR:AT5G35360.1); Has 35200 Blast hits to 30603 proteins in 3073 species: Archae - 603; Bacteria - 22615; Metazoa - 922; Fungi - 892; Plants - 784; Viruses - 0; Other Eukaryotes - 9384 (source: NCBI BLink).
Protein Annotations
EnsemblPlants:AT1G03090EnsemblPlants:AT1G03090.1entrez:838362hmmpanther:PTHR18866Pfam:PF00289Pfam:PF00364Pfam:PF02785
Pfam:PF02786Pfscan:PS50968Pfscan:PS50975Pfscan:PS50979scanprosite:PS00188scanprosite:PS00866scanprosite:PS00867
SUPFAM:SSF56059tair10-symbols:MCCA
Coordinates (TAIR10) chr1:+:739715..743819
Molecular Weight (calculated) 78373.40 Da
IEP (calculated) 6.78
GRAVY (calculated) -0.28
Length 714 amino acids
Sequence (TAIR10)
(BLAST)
001: MSMMTVWALR RNVRRKNHSM LVRYISGSAS MKPKEQCIEK ILVANRGEIA CRIMRTAKRL GIQTVAVYSD ADRDSLHVKS ADEAVRIGPP SARLSYLSGV
101: TIMEAAARTG AQAIHPGYGF LSESSDFAQL CEDSGLTFIG PPASAIRDMG DKSASKRIMG AAGVPLVPGY HGHEQDIDHM KSEAEKIGYP IIIKPTHGGG
201: GKGMRIVQSG KDFADSFLGA QREAAASFGV NTILLEKYIT RPRHIEVQIF GDKHGNVLHL YERDCSVQRR HQKIIEEAPA AVGYYNAGTV EFIVDTESDQ
301: FYFMEMNTRL QVEHPVTEMI VGQDLVEWQI RVANGEPLPL SQSEVPMSGH AFEARIYAEN VPKGFLPATG VLNHYRPVAV SPSVRVETGV EQGDTVSMHY
401: DPMIAKLVVW GGNRGEALVK LKDCLSNFQV AGVPTNINFL QKLASHKEFA VGNVETHFIE HHKSDLFADE SNPAATEVAY KAVKHSAALV AACISTIEHS
501: TWNESNHGKV PSIWYSNPPF RVHHEAKQTI ELEWNNECEG TGSNLISLGV RYQPDGSYLI EEGNDSPSLE LRVTRAGKCD FRVEAAGLSM NVSLAAYLKD
601: GYKHIHIWHG SEHHQFKQKV GIEFSEDEEG VQHRTSSETS SHPPGTIVAP MAGLVVKVLV ENEAKVDQGQ PILVLEAMKM EHVVKAPSSG SIQDLKVKAG
701: QQVSDGSALF RIKG
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)