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AT1G02500.1
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
cytosol 1.000
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
  • PMID:31871212 (2020): mitochondrion
  • PMID:31615849 (2019): plastid plastid thylakoid
  • PMID:31520498 (2020): mitochondrion
  • PMID:31186290 (2019): cytosol None
  • PMID:30783145 (2019): extracellular region plant-type cell wall
  • PMID:29104584 (2017): nucleus nuclear matrix nucleolus
  • PMID:26572690 (2016): extracellular region plant-type cell wall
  • PMID:24124904 (2013): plastid
  • PMID:23673981 (2013): plastid plastid stroma plastoglobules
  • PMID:22550958 (2012): plastid
  • PMID:21166475 (2011): cytosol
  • PMID:19334764 (2009): plasma membrane
  • PMID:17317660 (2007): plasma membrane
  • PMID:14505352 (2003): nucleus
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : S-adenosylmethionine synthetase 1
Curator
Summary (TAIR10)
encodes a S-adenosylmethionine synthetase. SAM1 is regulated by protein S-nitrosylation. The covalent binding of nitric oxide (NO) to the Cys114 residue inhibits the enzyme activity.
Computational
Description (TAIR10)
S-adenosylmethionine synthetase 1 (SAM1); FUNCTIONS IN: methionine adenosyltransferase activity; INVOLVED IN: response to cadmium ion, response to salt stress, ethylene biosynthetic process, S-adenosylmethionine biosynthetic process; LOCATED IN: cell wall, plasma membrane, membrane; EXPRESSED IN: 30 plant structures; EXPRESSED DURING: 17 growth stages; CONTAINS InterPro DOMAIN/s: S-adenosylmethionine synthetase (InterPro:IPR002133), S-adenosylmethionine synthetase superfamily (InterPro:IPR022636), S-adenosylmethionine synthetase, N-terminal (InterPro:IPR022628), S-adenosylmethionine synthetase, C-terminal (InterPro:IPR022630), S-adenosylmethionine synthetase, conserved site (InterPro:IPR022631), S-adenosylmethionine synthetase, central domain (InterPro:IPR022629); BEST Arabidopsis thaliana protein match is: S-adenosylmethionine synthetase 2 (TAIR:AT4G01850.2); Has 10905 Blast hits to 10897 proteins in 2898 species: Archae - 12; Bacteria - 5497; Metazoa - 373; Fungi - 167; Plants - 706; Viruses - 1; Other Eukaryotes - 4149 (source: NCBI BLink).
Protein Annotations
BioCyc:ARA:AT1G02500-MONOMERBioCyc:ARA:GQT-680-MONOMERBioCyc:MetaCyc:AT1G02500-MONOMERBioGrid:24736
EC:2.5.1.6eggNOG:COG0192eggNOG:KOG1506EMBL:AC022521
EMBL:AF325061EMBL:AF428440EMBL:AY052311EMBL:AY061895
EMBL:AY087703EMBL:AY092955EMBL:CP002684EMBL:M55077
EMBL:Z17672EMBL:Z17762EnsemblPlants:AT1G02500EnsemblPlants:AT1G02500.1
EnsemblPlants:AT1G02500.2entrez:839501GeneID:839501Genevisible:P23686
GO:GO:0004478GO:GO:0005524GO:GO:0005618GO:GO:0005829
GO:GO:0005886GO:GO:0006556GO:GO:0006730GO:GO:0009651
GO:GO:0009693GO:GO:0016020GO:GO:0046686GO:GO:0046872
GO:GO:0071281Gramene:AT1G02500.1Gramene:AT1G02500.2gramene_plant_reactome:1119334
gramene_plant_reactome:6876869HAMAP:MF_00086HOGENOM:HOG000245710InParanoid:P23686
InterPro:IPR002133InterPro:IPR022628InterPro:IPR022629InterPro:IPR022630
InterPro:IPR022631InterPro:IPR022636KEGG:00270+2.5.1.6KEGG:ath:AT1G02500
KO:K00789MINT:MINT-8064442OMA:SVQHDECPaxDb:P23686
Pfam:P23686Pfam:PF00438Pfam:PF02772Pfam:PF02773
PhylomeDB:P23686PIR:C86155PIR:JN0131PIRSF:PIRSF000497
PRIDE:P23686PRO:PR:P23686PROSITE:PS00376PROSITE:PS00377
ProteinModelPortal:P23686Proteomes:UP000006548Reactome:R-ATH-156581Reactome:R-ATH-1614635
Reactome:R-ATH-2408508RefSeq:NP_171751.1RefSeq:NP_849577.1scanprosite:PS00376
scanprosite:PS00377SMR:P23686STRING:3702.AT1G02500.1SUPFAM:SSF55973
SWISS-2DPAGE:P99056TAIR:AT1G02500tair10-symbols:AtSAM1tair10-symbols:MAT1
tair10-symbols:SAM-1tair10-symbols:SAM1TIGRfam:TIGR01034TIGRFAMs:TIGR01034
UniGene:At.24731UniPathway:UPA00315UniProt:P23686
Coordinates (TAIR10) chr1:+:519037..520218
Molecular Weight (calculated) 43160.40 Da
IEP (calculated) 5.61
GRAVY (calculated) -0.31
Length 393 amino acids
Sequence (TAIR10)
(BLAST)
001: METFLFTSES VNEGHPDKLC DQISDAVLDA CLEQDPDSKV ACETCTKTNM VMVFGEITTK ATVDYEKIVR DTCRAIGFVS DDVGLDADKC KVLVNIEQQS
101: PDIAQGVHGH FTKCPEEIGA GDQGHMFGYA TDETPELMPL SHVLATKLGA RLTEVRKNGT CAWLRPDGKT QVTVEYYNDK GAMVPIRVHT VLISTQHDET
201: VTNDEIARDL KEHVIKPVIP EKYLDEKTIF HLNPSGRFVI GGPHGDAGLT GRKIIIDTYG GWGAHGGGAF SGKDPTKVDR SGAYIVRQAA KSVVANGMAR
301: RALVQVSYAI GVPEPLSVFV DTYETGLIPD KEILKIVKES FDFRPGMMTI NLDLKRGGNG RFLKTAAYGH FGRDDPDFTW EVVKPLKWDK PQA
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)