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AT1G01580.1
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
vacuole 0.996
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
Description (TAIR10) protein_coding : ferric reduction oxidase 2
Curator
Summary (TAIR10)
Encodes the low-iron-inducible ferric chelate reductase responsible for reduction of iron at the root surface. It is likely to be the major Fe(III) chelate reductase in Arabidopsis iron metabolism. Coordinately regulated with IRT1, the major transporter responsible for high-affinity iron uptake from the soil, at both transcriptional and posttranscriptional levels. Steady state mRNA levels are regulated by several metals. Its transcription is regulated by FIT1.
Computational
Description (TAIR10)
ferric reduction oxidase 2 (FRO2); CONTAINS InterPro DOMAIN/s: Ferredoxin reductase-type FAD-binding domain (InterPro:IPR017927), Ferric reductase, NAD binding (InterPro:IPR013121), FAD-binding 8 (InterPro:IPR013112), Riboflavin synthase-like beta-barrel (InterPro:IPR017938), Ferric reductase-like transmembrane component, N-terminal (InterPro:IPR013130); BEST Arabidopsis thaliana protein match is: ferric reduction oxidase 1 (TAIR:AT1G01590.1); Has 2711 Blast hits to 2707 proteins in 388 species: Archae - 5; Bacteria - 307; Metazoa - 560; Fungi - 1180; Plants - 483; Viruses - 0; Other Eukaryotes - 176 (source: NCBI BLink).
Protein Annotations
BioCyc:ARA:AT1G01580-MONOMERBioGrid:24646EC:1.16.1.7eggNOG:ENOG410XNZY
eggNOG:KOG0039EMBL:AC061957EMBL:AY302057EMBL:CP002684
EMBL:Y09581EnsemblPlants:AT1G01580EnsemblPlants:AT1G01580.1entrez:839411
GeneID:839411GO:GO:0000293GO:GO:0005886GO:GO:0006811
GO:GO:0009617GO:GO:0015688GO:GO:0016021GO:GO:0046872
GO:GO:0055072Gramene:AT1G01580.1gramene_pathway:1.16.1.7gramene_pathway:PWY-5934
hmmpanther:PTHR11972hmmpanther:PTHR11972:SF41HOGENOM:HOG000006154InParanoid:P92949
InterPro:IPR013112InterPro:IPR013121InterPro:IPR013130InterPro:IPR017927
InterPro:IPR017938KEGG:ath:AT1G01580OMA:RMFELFYPaxDb:P92949
Pfam:P92949Pfam:PF01794Pfam:PF08022Pfam:PF08030
Pfscan:PS51384PhylomeDB:P92949PIR:E86146PRIDE:P92949
PRO:PR:P92949PROSITE:PS51384ProteinModelPortal:P92949Proteomes:UP000006548
RefSeq:NP_171664.1SMR:P92949STRING:3702.AT1G01580.1SUPFAM:SSF52343
SUPFAM:SSF63380TAIR:AT1G01580tair10-symbols:ATFRO2tair10-symbols:FRD1
tair10-symbols:FRO2TMHMM:TMhelixUniGene:At.42640UniProt:P92949
Coordinates (TAIR10) chr1:+:209395..212810
Molecular Weight (calculated) 81505.60 Da
IEP (calculated) 9.74
GRAVY (calculated) 0.25
Length 725 amino acids
Sequence (TAIR10)
(BLAST)
001: MEIEKSNNGG SNPSAGEEFK DMIKGVTKFL MMVIFLGTIM LWIMMPTLTY RTKWLPHLRI KFGTSTYFGA TGTTLFMYMF PMMVVACLGC VYLHFKNRKS
101: PHHIDRETKG GVWSKLRKPM LVKGPLGIVS VTEITFLAMF VALLLWCFIT YLRNSFATIT PKSAAAHDES LWQAKLESAA LRLGLIGNIC LAFLFLPVAR
201: GSSLLPAMGL TSESSIKYHI WLGHMVMALF TVHGLCYIIY WASMHEISQM IMWDTKGVSN LAGEIALAAG LVMWATTYPK IRRRFFEVFF YTHYLYIVFM
301: LFFVLHVGIS FSFIALPGFY IFLVDRFLRF LQSRENVRLL AARILPSDTM ELTFSKNSKL VYSPTSIMFV NIPSISKLQW HPFTITSSSK LEPEKLSIVI
401: KKEGKWSTKL HQRLSSSDQI DRLAVSVEGP YGPASADFLR HEALVMVCGG SGITPFISVI RDLIATSQKE TCKIPKITLI CAFKKSSEIS MLDLVLPLSG
501: LETELSSDIN IKIEAFITRD NDAGDEAKAG KIKTLWFKPS LSDQSISSIL GPNSWLWLGA ILASSFLIFM IIIGIITRYY IYPIDHNTNK IYSLTSKTII
601: YILVISVSIM ATCSAAMLWN KKKYGKVESK QVQNVDRPSP TSSPTSSWGY NSLREIESTP QESLVQRTNL HFGERPNLKK LLLDVEGSSV GVLVCGPKKM
701: RQKVAEICSS GLAENLHFES ISFSW
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)