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AT1G01220.1
Subcellular Consensus
(Prediction and Experimental)
min: heatmap :max

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SUBAcon:
cytosol 1.000
ASURE: cytosol
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
  • PMID:25900983 (2015): Golgi trans-Golgi network
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : L-fucokinase/GDP-L-fucose pyrophosphorylase
Curator
Summary (TAIR10)
Encodes a bifunctional enzyme that has both L-fucokinase and GDP-L-fucose pyrophosphorylase activities. It catalyzes the two steps of the L-fucose salvage pathway for the generation of activated GDP-L-fucose. This pathway seems to be of minor importance for cell wall polysaccharide biosynthesis compared to the de novo GDP-L-fucose biosynthesis pathway in Arabidopsis.
Computational
Description (TAIR10)
L-fucokinase/GDP-L-fucose pyrophosphorylase (FKGP); FUNCTIONS IN: fucose-1-phosphate guanylyltransferase activity, fucokinase activity, ATP binding, galactokinase activity; INVOLVED IN: GDP-L-fucose salvage; LOCATED IN: cytoplasm; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Mevalonate/galactokinase (InterPro:IPR006206), Ribosomal protein S5 domain 2-type fold (InterPro:IPR020568), GHMP kinase (InterPro:IPR006204), L-fucokinase (InterPro:IPR012887), Ribosomal protein S5 domain 2-type fold, subgroup (InterPro:IPR014721), GHMP kinase, C-terminal (InterPro:IPR013750); Has 1878 Blast hits to 1819 proteins in 539 species: Archae - 59; Bacteria - 918; Metazoa - 155; Fungi - 3; Plants - 87; Viruses - 3; Other Eukaryotes - 653 (source: NCBI BLink).
Protein Annotations
EC:2.7.1.52EC:2.7.7.30eggNOG:ENOG4111FB6eggNOG:KOG4644
EMBL:AC023628EMBL:CP002684EnsemblPlants:AT1G01220EnsemblPlants:AT1G01220.1
entrez:839420Gene3D:3.30.230.10Gene3D:3.30.70.890GeneID:839420
Genevisible:Q9LNJ9GO:GO:0005524GO:GO:0005737GO:GO:0005975
GO:GO:0042352GO:GO:0046872GO:GO:0047341GO:GO:0050201
Gramene:AT1G01220.1gramene_pathway:2.7.1.52gramene_pathway:2.7.7.30gramene_pathway:PWY-6
hmmpanther:PTHR32463InParanoid:Q9LNJ9InterPro:IPR006204InterPro:IPR006206
InterPro:IPR012887InterPro:IPR013750InterPro:IPR014721InterPro:IPR020568
iPTMnet:Q9LNJ9KEGG:00052+2.7.1.6KEGG:00520+2.7.1.6KEGG:ath:AT1G01220
KO:K05305ncoils:CoilOMA:WSLERAGPaxDb:Q9LNJ9
Pfam:PF00288Pfam:PF07959Pfam:PF08544Pfam:Q9LNJ9
PIR:D86142PRIDE:Q9LNJ9PRINTS:PR00959PRO:PR:Q9LNJ9
ProteinModelPortal:Q9LNJ9Proteomes:UP000006548Reactome:R-ATH-6787639RefSeq:NP_563620.1
STRING:3702.AT1G01220.1SUPFAM:SSF54211SUPFAM:SSF55060TAIR:AT1G01220
tair10-symbols:AtFKGPtair10-symbols:FKGPUniGene:At.42659unipathway:UPA00214
UniProt:Q9LNJ9
Coordinates (TAIR10) chr1:+:91750..95552
Molecular Weight (calculated) 116358.00 Da
IEP (calculated) 6.24
GRAVY (calculated) -0.08
Length 1055 amino acids
Sequence (TAIR10)
(BLAST)
0001: MSKQRKKADL ATVLRKSWYH LRLSVRHPTR VPTWDAIVLT AASPEQAELY DWQLRRAKRM GRIASSTVTL AVPDPDGKRI GSGAATLNAI YALARHYEKL
0101: GFDLGPEMEV ANGACKWVRF ISAKHVLMLH AGGDSKRVPW ANPMGKVFLP LPYLAADDPD GPVPLLFDHI LAIASCARQA FQDQGGLFIM TGDVLPCFDA
0201: FKMTLPEDAA SIVTVPITLD IASNHGVIVT SKSESLAESY TVSLVNDLLQ KPTVEDLVKK DAILHDGRTL LDTGIISARG RAWSDLVALG CSCQPMILEL
0301: IGSKKEMSLY EDLVAAWVPS RHDWLRTRPL GELLVNSLGR QKMYSYCTYD LQFLHFGTSS EVLDHLSGDA SGIVGRRHLC SIPATTVSDI AASSVILSSE
0401: IAPGVSIGED SLIYDSTVSG AVQIGSQSIV VGIHIPSEDL GTPESFRFML PDRHCLWEVP LVGHKGRVIV YCGLHDNPKN SIHKDGTFCG KPLEKVLFDL
0501: GIEESDLWSS YVAQDRCLWN AKLFPILTYS EMLKLASWLM GLDDSRNKEK IKLWRSSQRV SLEELHGSIN FPEMCNGSSN HQADLAGGIA KACMNYGMLG
0601: RNLSQLCHEI LQKESLGLEI CKNFLDQCPK FQEQNSKILP KSRAYQVEVD LLRACGDEAK AIELEHKVWG AVAEETASAV RYGFREHLLE SSGKSHSENH
0701: ISHPDRVFQP RRTKVELPVR VDFVGGWSDT PPWSLERAGY VLNMAITLEG SLPIGTIIET TNQMGISIQD DAGNELHIED PISIKTPFEV NDPFRLVKSA
0801: LLVTGIVQEN FVDSTGLAIK TWANVPRGSG LGTSSILAAA VVKGLLQISN GDESNENIAR LVLVLEQLMG TGGGWQDQIG GLYPGIKFTS SFPGIPMRLQ
0901: VVPLLASPQL ISELEQRLLV VFTGQVRLAH QVLHKVVTRY LQRDNLLISS IKRLTELAKS GREALMNCEV DEVGDIMSEA WRLHQELDPY CSNEFVDKLF
1001: EFSQPYSSGF KLVGAGGGGF SLILAKDAEK AKELRQRLEE HAEFDVKVYN WSICI
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)