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AT1G01040.1
Subcellular Consensus
(Prediction and Experimental)

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SUBAcon:
nucleus 1.000
What is SUBAcon?
What is ASURE?
SUBAcon computations
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
Description (TAIR10) protein_coding : dicer-like 1
Curator
Summary (TAIR10)
Encodes a Dicer homolog. Dicer is a RNA helicase involved in microRNA processing. Mutations in this locus can result in embryo lethality. Embryo shape at seed maturity is globular-elongate. Other mutants convert the floral meristems to an indeterminate state, others yet show defects in ovule development. mRNA is expressed in all shoot tissues. DCL1 is able to produce miRNAs and siRNAs.
Computational
Description (TAIR10)
dicer-like 1 (DCL1); CONTAINS InterPro DOMAIN/s: Restriction endonuclease, type I, R subunit/Type III, Res subunit (InterPro:IPR006935), Double-stranded RNA-binding (InterPro:IPR001159), Argonaute/Dicer protein, PAZ (InterPro:IPR003100), Ribonuclease III (InterPro:IPR000999), Double-stranded RNA-binding-like (InterPro:IPR014720), DEAD-like helicase, N-terminal (InterPro:IPR014001), DNA/RNA helicase, C-terminal (InterPro:IPR001650), Helicase, superfamily 1/2, ATP-binding domain (InterPro:IPR014021), Dicer double-stranded RNA-binding fold (InterPro:IPR005034); BEST Arabidopsis thaliana protein match is: dicer-like 3 (TAIR:AT3G43920.2); Has 21958 Blast hits to 17420 proteins in 2982 species: Archae - 328; Bacteria - 11461; Metazoa - 3615; Fungi - 1668; Plants - 1373; Viruses - 45; Other Eukaryotes - 3468 (source: NCBI BLink).
Protein Annotations
BioCyc:ARA:AT1G01040-MONOMERBioCyc:ARA:GQT-1487-MONOMERBioGrid:24809DIP:DIP-33454NEC:3.1.26.-eggNOG:COG0571eggNOG:COG1111
eggNOG:KOG0701EMBL:AC007323EMBL:AF187317EMBL:AF292940EMBL:AF292941EMBL:CP002684EnsemblPlants:AT1G01040
EnsemblPlants:AT1G01040.1entrez:839574ExpressionAtlas:Q9SP32Gene3D:1.10.1520.10Gene3D:3.30.160.20Gene3D:3.40.50.300GeneID:839574
Genevisible:Q9SP32GO:GO:0003677GO:GO:0003723GO:GO:0004386GO:GO:0004525GO:GO:0005524GO:GO:0005634
GO:GO:0006396GO:GO:0016075GO:GO:0031047GO:GO:0046872HAMAP:MF_00104hmmpanther:PTHR14950hmmpanther:PTHR14950:SF3
HOGENOM:HOG000239675InParanoid:Q9SP32IntAct:Q9SP32InterPro:IPR000999InterPro:IPR001650InterPro:IPR003100InterPro:IPR005034
InterPro:IPR006935InterPro:IPR011907InterPro:IPR014001InterPro:IPR014720InterPro:IPR027417iPTMnet:Q9SP32PaxDb:Q9SP32
PDB:2LRSPDBsum:2LRSPfam:PF00035Pfam:PF00271Pfam:PF00636Pfam:PF02170Pfam:PF03368
Pfam:PF04851Pfam:PF14709Pfam:Q9SP32Pfscan:PS50137Pfscan:PS50142Pfscan:PS50821Pfscan:PS51192
Pfscan:PS51194Pfscan:PS51327PhylomeDB:Q9SP32PRIDE:Q9SP32PRO:PR:Q9SP32PROSITE:PS00517PROSITE:PS50137
PROSITE:PS50142PROSITE:PS50821PROSITE:PS51192PROSITE:PS51194PROSITE:PS51327ProteinModelPortal:Q9SP32Proteomes:UP000006548
RefSeq:NP_171612.1scanprosite:PS00517SMART:SM00358SMART:SM00487SMART:SM00490SMART:SM00535SMART:SM00949
SMR:Q9SP32STRING:3702.AT1G01040.2SUPFAM:SSF101690SUPFAM:SSF52540SUPFAM:SSF54768SUPFAM:SSF69065TAIR:AT1G01040
tair10-symbols:ASU1tair10-symbols:ATDCL1tair10-symbols:CAFtair10-symbols:DCL1tair10-symbols:EMB60tair10-symbols:EMB76tair10-symbols:SIN1
tair10-symbols:SUS1UniGene:At.22088UniGene:At.57123UniProt:Q9SP32
Coordinates (TAIR10) chr1:+:23519..31079
Molecular Weight (calculated) 213585.00 Da
IEP (calculated) 6.16
GRAVY (calculated) -0.42
Length 1909 amino acids
Sequence (TAIR10)
(BLAST)
0001: MVMEDEPREA TIKPSYWLDA CEDISCDLID DLVSEFDPSS VAVNESTDEN GVINDFFGGI DHILDSIKNG GGLPNNGVSD TNSQINEVTV TPQVIAKETV
0101: KENGLQKNGG KRDEFSKEEG DKDRKRARVC SYQSERSNLS GRGHVNNSRE GDRFMNRKRT RNWDEAGNNK KKRECNNYRR DGRDREVRGY WERDKVGSNE
0201: LVYRSGTWEA DHERDVKKVS GGNRECDVKA EENKSKPEER KEKVVEEQAR RYQLDVLEQA KAKNTIAFLE TGAGKTLIAI LLIKSVHKDL MSQNRKMLSV
0301: FLVPKVPLVY QQAEVIRNQT CFQVGHYCGE MGQDFWDSRR WQREFESKQV LVMTAQILLN ILRHSIIRME TIDLLILDEC HHAVKKHPYS LVMSEFYHTT
0401: PKDKRPAIFG MTASPVNLKG VSSQVDCAIK IRNLETKLDS TVCTIKDRKE LEKHVPMPSE IVVEYDKAAT MWSLHETIKQ MIAAVEEAAQ ASSRKSKWQF
0501: MGARDAGAKD ELRQVYGVSE RTESDGAANL IHKLRAINYT LAELGQWCAY KVGQSFLSAL QSDERVNFQV DVKFQESYLS EVVSLLQCEL LEGAAAEKVA
0601: AEVGKPENGN AHDEMEEGEL PDDPVVSGGE HVDEVIGAAV ADGKVTPKVQ SLIKLLLKYQ HTADFRAIVF VERVVAALVL PKVFAELPSL SFIRCASMIG
0701: HNNSQEMKSS QMQDTISKFR DGHVTLLVAT SVAEEGLDIR QCNVVMRFDL AKTVLAYIQS RGRARKPGSD YILMVERGNV SHAAFLRNAR NSEETLRKEA
0801: IERTDLSHLK DTSRLISIDA VPGTVYKVEA TGAMVSLNSA VGLVHFYCSQ LPGDRYAILR PEFSMEKHEK PGGHTEYSCR LQLPCNAPFE ILEGPVCSSM
0901: RLAQQAVCLA ACKKLHEMGA FTDMLLPDKG SGQDAEKADQ DDEGEPVPGT ARHREFYPEG VADVLKGEWV SSGKEVCESS KLFHLYMYNV RCVDFGSSKD
1001: PFLSEVSEFA ILFGNELDAE VLSMSMDLYV ARAMITKASL AFKGSLDITE NQLSSLKKFH VRLMSIVLDV DVEPSTTPWD PAKAYLFVPV TDNTSMEPIK
1101: GINWELVEKI TKTTAWDNPL QRARPDVYLG TNERTLGGDR REYGFGKLRH NIVFGQKSHP TYGIRGAVAS FDVVRASGLL PVRDAFEKEV EEDLSKGKLM
1201: MADGCMVAED LIGKIVTAAH SGKRFYVDSI CYDMSAETSF PRKEGYLGPL EYNTYADYYK QKYGVDLNCK QQPLIKGRGV SYCKNLLSPR FEQSGESETV
1301: LDKTYYVFLP PELCVVHPLS GSLIRGAQRL PSIMRRVESM LLAVQLKNLI SYPIPTSKIL EALTAASCQE TFCYERAELL GDAYLKWVVS RFLFLKYPQK
1401: HEGQLTRMRQ QMVSNMVLYQ FALVKGLQSY IQADRFAPSR WSAPGVPPVF DEDTKDGGSS FFDEEQKPVS EENSDVFEDG EMEDGELEGD LSSYRVLSSK
1501: TLADVVEALI GVYYVEGGKI AANHLMKWIG IHVEDDPDEV DGTLKNVNVP ESVLKSIDFV GLERALKYEF KEKGLLVEAI THASRPSSGV SCYQRLEFVG
1601: DAVLDHLITR HLFFTYTSLP PGRLTDLRAA AVNNENFARV AVKHKLHLYL RHGSSALEKQ IREFVKEVQT ESSKPGFNSF GLGDCKAPKV LGDIVESIAG
1701: AIFLDSGKDT TAAWKVFQPL LQPMVTPETL PMHPVRELQE RCQQQAEGLE YKASRSGNTA TVEVFIDGVQ VGVAQNPQKK MAQKLAARNA LAALKEKEIA
1801: ESKEKHINNG NAGEDQGENE NGNKKNGHQP FTRQTLNDIC LRKNWPMPSY RCVKEGGPAH AKRFTFGVRV NTSDRGWTDE CIGEPMPSVK KAKDSAAVLL
1901: LELLNKTFS
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)