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AT4G39640.1
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
extracellular 1.000
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
  • PMID:31673584 (2019): extracellular region plant-type cell wall
  • PMID:31615849 (2019): plastid plastid thylakoid
  • PMID:30961429 (2019): nucleus
  • PMID:30783145 (2019): extracellular region apoplast
  • PMID:30783145 (2019): extracellular region plant-type cell wall
  • PMID:28865150 (2017): extracellular region plant-type cell wall
  • PMID:28155257 (2017): extracellular region plant-type cell wall
  • PMID:26572690 (2016): extracellular region plant-type cell wall
  • PMID:23903016 (2013): plant-type vacuole plant-type vacuole membrane
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : gamma-glutamyl transpeptidase 1
Curator
Summary (TAIR10)
The gene encodes a gamma-glutamyltransferase (AKA gamma-glutamyl transpeptidase, EC 2.3.2.2) that is located in vascular tissues (predominantly phloem) of leaves and is involved in the degradation of glutathione. The encoded enzyme also mitigates oxidative stress by metabolizing GSSG (oxidized form of GSH - glutathione) in the apoplast.
Computational
Description (TAIR10)
gamma-glutamyl transpeptidase 1 (GGT1); FUNCTIONS IN: gamma-glutamyltransferase activity, glutathione gamma-glutamylcysteinyltransferase activity; INVOLVED IN: response to oxidative stress, glutathione catabolic process; LOCATED IN: apoplast, plant-type cell wall; EXPRESSED IN: 26 plant structures; EXPRESSED DURING: 10 growth stages; CONTAINS InterPro DOMAIN/s: Gamma-glutamyltranspeptidase (InterPro:IPR000101); BEST Arabidopsis thaliana protein match is: gamma-glutamyl transpeptidase 2 (TAIR:AT4G39650.1); Has 9168 Blast hits to 9144 proteins in 1483 species: Archae - 86; Bacteria - 4247; Metazoa - 703; Fungi - 305; Plants - 110; Viruses - 1; Other Eukaryotes - 3716 (source: NCBI BLink).
Protein Annotations
BioCyc:ARA:AT4G39640-MONOMERBioCyc:ARA:GQT-2509-MONOMERBRENDA:2.3.2.2EC:2.3.2.2
EC:3.4.19.13eggNOG:COG0405eggNOG:KOG2410EMBL:AK317779
EMBL:AL022605EMBL:AL161595EMBL:AY069872EMBL:BT000495
EMBL:CP002687EnsemblPlants:AT4G39640EnsemblPlants:AT4G39640.1EnsemblPlants:AT4G39640.2
entrez:830118GeneID:830118Genevisible:Q8VYW6GO:GO:0003840
GO:GO:0006751GO:GO:0006979GO:GO:0009505GO:GO:0009506
GO:GO:0016756GO:GO:0036374GO:GO:0048046Gramene:AT4G39640.1
Gramene:AT4G39640.2gramene_pathway:2.3.2.2gramene_pathway:PWY-4041gramene_pathway:PWYQT-4432
hmmpanther:PTHR11686hmmpanther:PTHR11686:SF9HOGENOM:HOG000175620InParanoid:Q8VYW6
InterPro:IPR000101InterPro:IPR029055iPTMnet:Q8VYW6KEGG:00430+2.3.2.2
KEGG:00460+2.3.2.2KEGG:00480+2.3.2.2+3.4.19.13KEGG:ath:AT4G39640KO:K18592
MEROPS:T03.008OMA:MWNQIDDPANTHER:PTHR11686PaxDb:Q8VYW6
Pfam:PF01019Pfam:Q8VYW6PhylomeDB:Q8VYW6PIR:T05001
PRIDE:Q8VYW6PRINTS:PR01210PRO:PR:Q8VYW6ProteinModelPortal:Q8VYW6
Proteomes:UP000006548Reactome:R-ATH-174403Reactome:R-ATH-2142691Reactome:R-ATH-5423646
RefSeq:NP_195674.2RefSeq:NP_974717.1SMR:Q8VYW6STRING:3702.AT4G39640.1
SUPFAM:SSF56235TAIR:AT4G39640tair10-symbols:GGT1TIGRfam:TIGR00066
TIGRFAMs:TIGR00066UniGene:At.21562UniPathway:UPA00204UniProt:Q8VYW6
Coordinates (TAIR10) chr4:+:18400608..18402861
Molecular Weight (calculated) 61193.40 Da
IEP (calculated) 10.06
GRAVY (calculated) -0.05
Length 572 amino acids
Sequence (TAIR10)
(BLAST)
001: MSLVRTVTIV LFIIAFLQNA AAQKRQQSIV KSRGAVATDD GRCSVIGMRV LREGGNAIDA SVAAALCLGV VSPASSGIGG GAFTVVKIAG GKEIAYDSRE
101: TAPLRATENM YGGNVDLKKK GALSVGVPGE VAGLFTAWKQ HGKLPWKRLV TPAEKLAEGF KISKYLYMQM NATRSDILAD KGLSDLFVSN GELKKPGTIC
201: HNPKLALTLK LIGEYGPKAF YNGTVGVNLA RDIKKSGGII TLKDLQSYRV KIKEPLSADI LGYRVLGMPP PSSGGAAMML VLNILSQYGI PSGVSGPLGV
301: HRLIEALKHA FAVRMNLGDP DFTDVTKVVS DMLSPKFAKD LKSKINDQKT FDPKYYGGMW NQIDDHGTSH LSIIDRERNA VSMTSTINGY FGALMLSPST
401: GIVLNNEMDD FSIPMKSNGN LDVPPPAPAN FIRPGKRPLS SMSPTIVLKD GKVKAAVGAS GGANIIAGTT EVYLNHFFLK MDPLSSVLAP RIYHQLIPNR
501: ASYENWTTVF NDHFEIPKAT RVVLEKKGHV LSPIAGGTIA QFIVQESGEN SGGRSELVAV SDPRKGGFPS GY
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)