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AT4G37270.1
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
plastid 1.000
ASURE: plastid
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : heavy metal atpase 1
Curator
Summary (TAIR10)
Encodes a P1B-type ATPases that is localized to the chloroplast envelope and is involved in the transport of Cu into chloroplasts. It is essential for growth under high light conditions.
Computational
Description (TAIR10)
heavy metal atpase 1 (HMA1); FUNCTIONS IN: copper-exporting ATPase activity, ATPase activity, calcium-transporting ATPase activity, zinc transporting ATPase activity, cadmium-transporting ATPase activity; INVOLVED IN: cellular copper ion homeostasis, calcium ion transport, response to toxin, zinc ion homeostasis, response to light intensity; LOCATED IN: chloroplast, chloroplast envelope; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Haloacid dehalogenase-like hydrolase (InterPro:IPR005834), ATPase, P-type, heavy metal translocating (InterPro:IPR006416), ATPase, P-type, ATPase-associated domain (InterPro:IPR008250), ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter (InterPro:IPR001757), ATPase, P-type, heavy metal-(Cd/Co/Hg/Pb/Zn)-translocating (InterPro:IPR006404), ATPase, P-type phosphorylation site (InterPro:IPR018303); BEST Arabidopsis thaliana protein match is: heavy metal atpase 2 (TAIR:AT4G30110.1); Has 36740 Blast hits to 31592 proteins in 3081 species: Archae - 714; Bacteria - 24289; Metazoa - 3807; Fungi - 1794; Plants - 1612; Viruses - 8; Other Eukaryotes - 4516 (source: NCBI BLink).
Protein Annotations
BioCyc:ARA:AT4G37270-MONOMEREC:3.6.3.3EC:3.6.3.5eggNOG:COG2217
eggNOG:KOG0207EMBL:AJ400906EMBL:AJ872069EMBL:AL161591
EMBL:CP002687EMBL:Z99707EnsemblPlants:AT4G37270EnsemblPlants:AT4G37270.1
entrez:829881Gene3D:1.20.1110.10Gene3D:2.70.150.10Gene3D:3.40.1110.10
Gene3D:3.40.50.1000GeneID:829881Genevisible:Q9M3H5GO:GO:0005524
GO:GO:0005887GO:GO:0006878GO:GO:0008551GO:GO:0009507
GO:GO:0009536GO:GO:0009642GO:GO:0009706GO:GO:0009941
GO:GO:0015633GO:GO:0016463GO:GO:0016887GO:GO:0046872
GO:GO:0055069GO:GO:0071577Gramene:AT4G37270.1hmmpanther:PTHR24093
hmmpanther:PTHR24093:SF272HOGENOM:HOG000250399InParanoid:Q9M3H5InterPro:IPR001757
InterPro:IPR008250InterPro:IPR018303InterPro:IPR023214InterPro:IPR023298
InterPro:IPR023299InterPro:IPR027256KEGG:ath:AT4G37270OMA:FKSEDES
PaxDb:Q9M3H5Pfam:PF00122Pfam:PF00702Pfam:Q9M3H5
PhylomeDB:Q9M3H5PIR:D85440PRIDE:Q9M3H5PRO:PR:Q9M3H5
PROSITE:PS00154ProteinModelPortal:Q9M3H5Proteomes:UP000006548RefSeq:NP_195444.1
scanprosite:PS00154SMR:Q9M3H5STRING:3702.AT4G37270.1SUPFAM:0049471
SUPFAM:0049473SUPFAM:SSF56784TAIR:AT4G37270tair10-symbols:ATHMA1
tair10-symbols:HMA1TCDB:3.A.3.6.6TIGRfam:TIGR01494TIGRfam:TIGR01525
TIGRFAMs:TIGR01494TIGRFAMs:TIGR01525TMHMM:TMhelixUniGene:At.56989
UniGene:At.74483UniProt:Q9M3H5
Coordinates (TAIR10) chr4:-:17541987..17546352
Molecular Weight (calculated) 88193.70 Da
IEP (calculated) 7.96
GRAVY (calculated) 0.12
Length 819 amino acids
Sequence (TAIR10)
(BLAST)
001: MEPATLTRSS SLTRFPYRRG LSTLRLARVN SFSILPPKTL LRQKPLRISA SLNLPPRSIR LRAVEDHHHD HHHDDEQDHH NHHHHHHQHG CCSVELKAES
101: KPQKMLFGFA KAIGWVRLAN YLREHLHLCC SAAAMFLAAA VCPYLAPEPY IKSLQNAFMI VGFPLVGVSA SLDALMDIAG GKVNIHVLMA LAAFASVFMG
201: NALEGGLLLA MFNLAHIAEE FFTSRSMVDV KELKESNPDS ALLIEVHNGN VPNISDLSYK SVPVHSVEVG SYVLVGTGEI VPVDCEVYQG SATITIEHLT
301: GEVKPLEAKA GDRVPGGARN LDGRMIVKAT KAWNDSTLNK IVQLTEEAHS NKPKLQRWLD EFGENYSKVV VVLSLAIAFL GPFLFKWPFL STAACRGSVY
401: RALGLMVAAS PCALAVAPLA YATAISSCAR KGILLKGAQV LDALASCHTI AFDKTGTLTT GGLTCKAIEP IYGHQGGTNS SVITCCIPNC EKEALAVAAA
501: MEKGTTHPIG RAVVDHSVGK DLPSIFVESF EYFPGRGLTA TVNGVKTVAE ESRLRKASLG SIEFITSLFK SEDESKQIKD AVNASSYGKD FVHAALSVDQ
601: KVTLIHLEDQ PRPGVSGVIA ELKSWARLRV MMLTGDHDSS AWRVANAVGI TEVYCNLKPE DKLNHVKNIA REAGGGLIMV GEGINDAPAL AAATVGIVLA
701: QRASATAIAV ADILLLRDNI TGVPFCVAKS RQTTSLVKQN VALALTSIFL AALPSVLGFV PLWLTVLLHE GGTLLVCLNS VRGLNDPSWS WKQDIVHLIN
801: KLRSQEPTSS SSNSLSSAH
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)