AT3G45290.1
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Subcellular Consensus
(Prediction and Experimental) min:  :max.
SUBAcon:plasma membrane 1.000 ASURE: plasma membrane What is SUBAcon? |
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| Experimental Localisations and PPI |
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SUBAcon links
AGI-AGI relationships |
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| Description (TAIR10) | protein_coding : Seven transmembrane MLO family protein | ||||||||||||||||||||||||||||||||||||||||
| Curator Summary (TAIR10) |
A member of a large family of seven-transmembrane domain proteins specific to plants, homologs of the barley mildew resistance locus o (MLO) protein. The Arabidopsis genome contains 15 genes encoding MLO proteins, with localization in plasma membrane. Phylogenetic analysis revealed four clades of closely-related AtMLO genes. ATMLO3 belongs to the clade IV, with AtMLO2, AtMLO6 and AtMLO12. The gene is expressed during early seedling growth, in primary root and lateral root primordia, in fruit abscission zone, in vascular system of cotyledons and in trichomes of young leaves,; it was not expressed in mature rosette leaves, as shown by GUS activity patterns. The expression of several phylogenetically closely-related AtMLO genes showed similar or overlapping tissue specificity and analogous responsiveness to external stimuli, suggesting functional redundancy, co-function, or antagonistic function(s). | ||||||||||||||||||||||||||||||||||||||||
| Computational Description (TAIR10) |
MILDEW RESISTANCE LOCUS O 3 (MLO3); FUNCTIONS IN: calmodulin binding; INVOLVED IN: cell death, defense response; LOCATED IN: integral to membrane, plasma membrane; EXPRESSED IN: 29 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Mlo-related protein (InterPro:IPR004326); BEST Arabidopsis thaliana protein match is: Seven transmembrane MLO family protein (TAIR:AT2G39200.1); Has 534 Blast hits to 527 proteins in 60 species: Archae - 0; Bacteria - 10; Metazoa - 0; Fungi - 0; Plants - 520; Viruses - 0; Other Eukaryotes - 4 (source: NCBI BLink). | ||||||||||||||||||||||||||||||||||||||||
| Protein Annotations |
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| Coordinates (TAIR10) | chr3:+:16617586..16621352 | ||||||||||||||||||||||||||||||||||||||||
| Molecular Weight (calculated) | 58565.70 Da | ||||||||||||||||||||||||||||||||||||||||
| IEP (calculated) | 7.56 | ||||||||||||||||||||||||||||||||||||||||
| GRAVY (calculated) | -0.04 | ||||||||||||||||||||||||||||||||||||||||
| Length | 508 amino acids | ||||||||||||||||||||||||||||||||||||||||
| Sequence (TAIR10) (BLAST) |
001: MTDKEESNHS SEVGAVRSLQ ETPTWALATV CFFFIAVSIC LERLINLLST RLKKNRKTSL LEAVEKLKSV LMVLGFMSLM LNVTEGEVSK ICIPIKYANR 101: MLPCRKTIKS HNDVSEDDDD DDGDNHDNSF FHQCSSKGKT SLISEEGLTQ LSYFFFVLAC MHILCNLAIL LLGMAKMRKW NSWEKETQTV EYLAANDPNR 201: FRITRDTTFA RRHLSSWTET SFQLWIKCFF RQFYNSVAKV DYLTLRHGFI FAHVSSNNAF NFQNYIQRSL HEDFKTVVGI SPLMWLTVVI FMLLDVSGWR 301: VYFYMSFVPL IIVLVIGTKL EMIVAKMAVT IKENNSVIRG TPLVESNDTH FWFSNPRFLL SILHYTLFLN TFEMAFIVWI TWQFGINSCY HDNQGIIITR 401: LVLAVTVQFL SSYITLPLYA IVTQMGSSYK RAILEEQLAN VLRHWQGMVR DKKKTIQTPD TDNNSNNNNG DIDSGESPVQ TEVASEFRFS GRQSPILQEI 501: QIQEKTER |
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| See Also |
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Citation
If you find this resource useful please cite one of the following publications:
Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)
Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)