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AT3G20475.1
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
nucleus 1.000
ASURE: nucleus
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : MUTS-homologue 5
Curator
Summary (TAIR10)
Encodes MSH5, a homologue of the MutS-homolog family of genes required for normal levels of recombination in budding yeast, mouse and Caenorhabditis elegans. Involved in meiotic recombination. Required for the formation of Class I interference-sensitive crossovers. Transcripts of AtMSH5 are specific to reproductive tissues and expression of the protein is abundant during prophase I of meiosis. Involved in meiotic recombination. Required for the formation of Class I interference-sensitive crossovers.
Computational
Description (TAIR10)
MUTS-homologue 5 (MSH5); FUNCTIONS IN: damaged DNA binding, mismatched DNA binding, ATP binding; INVOLVED IN: mismatch repair, chiasma assembly, reciprocal meiotic recombination; LOCATED IN: condensed nuclear chromosome; EXPRESSED IN: male gametophyte, flower, pollen tube; EXPRESSED DURING: L mature pollen stage, M germinated pollen stage, IL.00 inflorescence just visible; CONTAINS InterPro DOMAIN/s: DNA mismatch repair protein MutS, core (InterPro:IPR007696), DNA mismatch repair protein MutS, C-terminal (InterPro:IPR000432); BEST Arabidopsis thaliana protein match is: MUTS homolog 2 (TAIR:AT3G18524.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).
Protein Annotations
eggNOG:COG0249eggNOG:KOG0219eggNOG:KOG0221EMBL:AB024036
EMBL:AK221687EMBL:AK230222EMBL:BT012280EMBL:CP002686
EMBL:EF471448EnsemblPlants:AT3G20475EnsemblPlants:AT3G20475.1entrez:821593
Gene3D:3.40.50.300GeneID:821593Genevisible:F4JEP5GO:GO:0000794
GO:GO:0000795GO:GO:0005524GO:GO:0007131GO:GO:0010777
GO:GO:0030983GO:GO:0043073GO:GO:0045143GO:GO:0051026
Gramene:AT3G20475.1hmmpanther:PTHR11361hmmpanther:PTHR11361:SF20HOGENOM:HOG000006649
InParanoid:F4JEP5InterPro:IPR000432InterPro:IPR007696InterPro:IPR011184
InterPro:IPR027417KEGG:ath:AT3G20475KO:K08741OMA:LAFKKFV
PaxDb:F4JEP5Pfam:F4JEP5Pfam:PF00488Pfam:PF05192
PIRSF:PIRSF005813PRIDE:F4JEP5PRO:PR:F4JEP5PROSITE:PS00486
ProteinModelPortal:F4JEP5Proteomes:UP000006548RefSeq:NP_188683.3scanprosite:PS00486
SMART:SM00533SMART:SM00534SMR:F4JEP5STRING:3702.AT3G20475.1
SUPFAM:SSF48334SUPFAM:SSF52540TAIR:AT3G20475tair10-symbols:ATMSH5
tair10-symbols:MSH5UniGene:At.50208UniProt:F4JEP5
Coordinates (TAIR10) chr3:+:7143546..7150811
Molecular Weight (calculated) 91127.90 Da
IEP (calculated) 4.90
GRAVY (calculated) -0.00
Length 807 amino acids
Sequence (TAIR10)
(BLAST)
001: MEEMEDTETE PQVYMACIQH GRRVGVSYYD CSVRQLHVLE FWEEDCSDFT LINMVKYQAK PSIIYASTKS EESFVAALQQ NDGTDETTMV KLVKSSTFSY
101: EQAWHRLVYL RVTGMDDGLN IKERICYLSS MMDVGSEVQV RVSGGLLAIL ESERIVETLE QNESGSASIA IDSVMEVPLN KFLKLDAAAH EALQIFQTDK
201: HPSHMGIGRA KEGFSVFGMM NKCATPMGRR LLRSWFMRPI LDLEVLDRRL NAISFFISSV ELMASLRETL KSVKDISHLL KKFNSPTSLC TSNDWTAFLK
301: SISALLHVNK IFEVGVSESL REHMRRFNLD IIEKAGLCIS TELDYVYELV IGVIDVTRSK ERGYQTLVKE GFCAELDELR QIYEELPEFL QEVSAMELEH
401: FPHLHKEKLP PCIVYIQQIG YLMCIFGEKL DETALNRLTE FEFAFSDMDG ETQRFFYHTS KTRELDNLLG DIYHKILDME RAIIRDLLSH TLLFSAHLLK
501: AVNFVAELDC ILSLACVAHQ NNYVRPVLTV ESLLDIRNGR HVLQEMAVDT FIPNDTEIND NGRIHIITGP NYSGKSIYVK QVALIVFLSH IGSFVPADAA
601: TVGLTDRIFC AMGSKFMTAE QSTFMIDLHQ VGMMLRQATS RSLCLLDEFG KGTLTEDGIG LLGGTISHFA TCAEPPRVVV CTHLTELLNE SCLPVSEKIK
701: FYTMSVLRPD TESANMEEIV FLYRLIPGQT LLSYGLHCAL LAGVPEEVVK RAAIVLDAFE SNNNVDKLSL DKISSQDQAF KDAVDKFAEL DISKGDIHAF
801: FQDIFTS
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)