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AT2G26260.1
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
golgi 0.582
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : 3beta-hydroxysteroid-dehydrogenase/decarboxylase isoform 2
Curator
Summary (TAIR10)
Encodes an enzyme with 3&#946;-hydroxysteroid dehydrogenase/C4-decarboxylase activity <i>in vitro</i>. The activity of the enzyme was determined using microsomal extracts of yeast overexpressing the <i>Arabidopsis</i> gene. Cytosolic fractions failed to be associated to the activity, leading to the speculation that the enzyme is membrane-bound.
Computational
Description (TAIR10)
3beta-hydroxysteroid-dehydrogenase/decarboxylase isoform 2 (3BETAHSD/D2); FUNCTIONS IN: 3-beta-hydroxy-delta5-steroid dehydrogenase activity, sterol-4-alpha-carboxylate 3-dehydrogenase (decarboxylating) activity; INVOLVED IN: steroid biosynthetic process, metabolic process; LOCATED IN: membrane; EXPRESSED IN: 12 plant structures; EXPRESSED DURING: 4 anthesis, petal differentiation and expansion stage, E expanded cotyledon stage, D bilateral stage; CONTAINS InterPro DOMAIN/s: Reticulon (InterPro:IPR003388), NAD(P)-binding domain (InterPro:IPR016040), 3-beta hydroxysteroid dehydrogenase/isomerase (InterPro:IPR002225); BEST Arabidopsis thaliana protein match is: 3beta-hydroxysteroid-dehydrogenase/decarboxylase isoform 1 (TAIR:AT1G47290.2); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).
Protein Annotations
BioCyc:ARA:GQT-1992-MONOMERBioCyc:MetaCyc:AT2G26260-MONOMEREC:1.1.1.170eggNOG:COG0451
eggNOG:KOG1430EMBL:AC004484EMBL:AK176177EMBL:BX818951
EMBL:CP002685EMBL:DQ302749EnsemblPlants:AT2G26260EnsemblPlants:AT2G26260.1
entrez:817166ExpressionAtlas:Q67ZE1Gene3D:3.40.50.720GeneID:817166
Genevisible:Q67ZE1GO:GO:0003854GO:GO:0005789GO:GO:0016020
GO:GO:0016021GO:GO:0016126GO:GO:0047012gramene_pathway:1.1.1.-
gramene_pathway:1.1.1.170gramene_pathway:PWY-6663gramene_pathway:PWY66-341hmmpanther:PTHR10366
hmmpanther:PTHR10366:SF471HOGENOM:HOG000167989InParanoid:Q67ZE1InterPro:IPR002225
InterPro:IPR003388InterPro:IPR016040KEGG:ath:AT2G26260KO:K07748
OMA:FKSFACKPaxDb:Q67ZE1Pfam:PF01073Pfam:PF02453
Pfam:Q67ZE1Pfscan:PS50845PhylomeDB:Q67ZE1PIR:C84658
PRIDE:Q67ZE1PRO:PR:Q67ZE1PROSITE:PS50845ProteinModelPortal:Q67ZE1
Proteomes:UP000006548Reactome:R-ATH-191273RefSeq:NP_001031422.1RefSeq:NP_180194.2
SMR:Q67ZE1STRING:3702.AT2G26260.1SUPFAM:SSF51735TAIR:AT2G26260
tair10-symbols:3BETAHSD/D2tair10-symbols:AT3BETAHSD/D2TMHMM:TMhelixUniGene:At.38921
UniPathway:UPA00770UniProt:Q67ZE1
Coordinates (TAIR10) chr2:+:11178237..11182872
Molecular Weight (calculated) 61707.80 Da
IEP (calculated) 8.58
GRAVY (calculated) 0.15
Length 564 amino acids
Sequence (TAIR10)
(BLAST)
001: MSPAATETER WCVVTGGRGF AARHLVEMLV RYEMFCVRIA DLAPAIMLDP QEGNGVLDEG LRSGRVQYIS ADLRDKSQVV KAFQGAEVVF HMAAPDSSIN
101: NHQLQYSVNV QGTQNVIDAC VDVGVKRLIY TSSPSVVFDG VHGILNGTES MAYPIKHNDS YSATKAEGEE LIMKANGRNG LLTCCIRPSS IFGPGDRLLV
201: PSLVAAARAG KSKFIIGDGN NLYDFTYVEN VAHAHVCAER ALASGGDVST KAAGQAYFIT NMEPIKFWEF MSQLLDGLGY ERPSIKIPAF IMMPIAHLVE
301: LTYKVLGPYG MTVPQLTPSR VRLLSCSRTF DSTKAKDRLG YAPVVPLQEG IRRTIDSFSH LTAGSQSKRE GPSKASRILG GGKVADTLLW KDLKQTLIAI
401: FILISIYYNF VATGSTVVTA LSKALLVASV FLFLHGILPE KIFGYTVEKI PASQFHLSKD SSHDLSLSVI SSWNTTVKAL RSLCQGNDWS FFFKVVFVLL
501: ALSLAGAISL HSIFVIGLPI AFLAFLVYEK KEQEIDSIVV SFKSFACKHK SDVYEKLFGS KKHD
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)