AT1G16420.1
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Subcellular Consensus
(Prediction and Experimental) min:  :max.
SUBAcon:cytosol 0.499 plasma membrane 0.234 What is SUBAcon? |
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| Experimental Localisations and PPI |
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SUBAcon links
AGI-AGI relationships |
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| Description (TAIR10) | protein_coding : metacaspase 8 | ||||||||||||||||||||||||||||||||||||||||||||||||
| Curator Summary (TAIR10) |
Encodes a metacaspase (cysteine-type endopeptidase) that is involved in promoting programmed cell death in response to hydrogen peroxide (H2O2), UV light, and methyl viologen (MV). Transcript levels rise in response to UV-C, H2O2, and MV. In vitro assays demonstrate that this enzyme has a preference for cleaving after an arginine residue, and it has a pH optimum of 8.0. | ||||||||||||||||||||||||||||||||||||||||||||||||
| Computational Description (TAIR10) |
metacaspase 8 (MC8); CONTAINS InterPro DOMAIN/s: Peptidase C14, caspase catalytic (InterPro:IPR011600); BEST Arabidopsis thaliana protein match is: metacaspase 7 (TAIR:AT1G79310.1); Has 1067 Blast hits to 1064 proteins in 261 species: Archae - 3; Bacteria - 286; Metazoa - 0; Fungi - 258; Plants - 304; Viruses - 0; Other Eukaryotes - 216 (source: NCBI BLink). | ||||||||||||||||||||||||||||||||||||||||||||||||
| Protein Annotations |
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| Coordinates (TAIR10) | chr1:-:5612304..5613829 | ||||||||||||||||||||||||||||||||||||||||||||||||
| Molecular Weight (calculated) | 42523.90 Da | ||||||||||||||||||||||||||||||||||||||||||||||||
| IEP (calculated) | 5.73 | ||||||||||||||||||||||||||||||||||||||||||||||||
| GRAVY (calculated) | -0.45 | ||||||||||||||||||||||||||||||||||||||||||||||||
| Length | 381 amino acids | ||||||||||||||||||||||||||||||||||||||||||||||||
| Sequence (TAIR10) (BLAST) |
001: MAKKALLIGI NYPGTAVELR GCVNDVHRMQ KCLIELYGFA NKDIVIMIDT DKSCIQPTGK NICDELDNLI ASGQSGDFLV FHYSGHGTRI PPGIEDSEDP 101: TGFDECITPC DMNLIKDQQF REMVSRVKEG CQLTIISDSC HSGGLIQEVK EQIGESHMKP VDKVKEQIEE SHMKQPKLGI ASYFLNIVMN LLATCGVSKS 201: QRDRGGGEES FRGEIELEKD ETLDIKTRYL PFESYLSLLK EQTGQTNIEP VRIRQTLLKL FGEDPSPNRQ RGLSDLGNCE VDAGDSGASR LNAVTDNGIL 301: LSGCQTDQRS EDVYVTRTGK AYGAFSDAIQ MILSAPRKDK KKITNKELVS EARVFLKKRG YSQRPGLYCH DRFVDKPFIC Y |
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| See Also |
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Citation
If you find this resource useful please cite one of the following publications:
Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)
Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)