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AT1G05830.1
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
nucleus 1.000
ASURE: nucleus
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : trithorax-like protein 2
Curator
Summary (TAIR10)
Encodes a homolog of trithorax, a histone-lysine N-methyltransferase. Paralog of ATX1. Unlike ATX1 which is involved in trimethylating of histone H3-mysine 4, ATX2 is involved in dimethylating of histone H3-lysine 4. ATX1 and ATX2 influence the expression of largely nonoverlapping gene sets. The expression pattern of ATX2 is also different from that of ATX1.
Computational
Description (TAIR10)
trithorax-like protein 2 (ATX2); FUNCTIONS IN: histone methyltransferase activity (H3-K4 specific), DNA binding; INVOLVED IN: histone H3-K4 methylation, regulation of transcription, DNA-dependent, regulation of transcription; LOCATED IN: nucleus; EXPRESSED IN: stigma, rosette leaf, male gametophyte, root; CONTAINS InterPro DOMAIN/s: SET domain (InterPro:IPR001214), Zinc finger, PHD-type, conserved site (InterPro:IPR019786), FY-rich, C-terminal (InterPro:IPR003889), Zinc finger, PHD-type (InterPro:IPR001965), FY-rich, N-terminal (InterPro:IPR003888), Post-SET domain (InterPro:IPR003616), FY-rich, C-terminal subgroup (InterPro:IPR018516), PWWP (InterPro:IPR000313), Zinc finger, FYVE/PHD-type (InterPro:IPR011011), FY-rich, N-terminal subgroup (InterPro:IPR018518), Zinc finger, PHD-finger (InterPro:IPR019787); BEST Arabidopsis thaliana protein match is: homologue of trithorax (TAIR:AT2G31650.1); Has 7263 Blast hits to 7069 proteins in 482 species: Archae - 2; Bacteria - 419; Metazoa - 3302; Fungi - 848; Plants - 1335; Viruses - 0; Other Eukaryotes - 1357 (source: NCBI BLink).
Protein Annotations
BioCyc:ARA:AT1G05830-MONOMERBioCyc:ARA:GQT-2042-MONOMEREC:2.1.1.43eggNOG:COG2940
eggNOG:COG5141eggNOG:KOG1080EMBL:AC009999EMBL:AK226560
EMBL:CP002684EnsemblPlants:AT1G05830EnsemblPlants:AT1G05830.1EnsemblPlants:AT1G05830.2
entrez:837093Gene3D:3.30.40.10GeneID:837093Genevisible:P0CB22
GO:GO:0005634GO:GO:0006355GO:GO:0008270GO:GO:0042800
GO:GO:0051568Gramene:AT1G05830.1Gramene:AT1G05830.2hmmpanther:PTHR13793
hmmpanther:PTHR13793:SF100HOGENOM:HOG000030783InParanoid:P0CB22InterPro:IPR000313
InterPro:IPR001214InterPro:IPR001965InterPro:IPR003616InterPro:IPR003888
InterPro:IPR003889InterPro:IPR011011InterPro:IPR013083InterPro:IPR019786
InterPro:IPR019787iPTMnet:P0CB22KEGG:ath:AT1G05830ncoils:Coil
OMA:DQRLPCYPaxDb:P0CB22Pfam:P0CB22Pfam:PF00855
Pfam:PF00856Pfam:PF05964Pfam:PF05965Pfam:PF13831
Pfam:PF13832Pfscan:PS50016Pfscan:PS50280Pfscan:PS50812
Pfscan:PS50868Pfscan:PS51542Pfscan:PS51543PhylomeDB:P0CB22
PIR:A86193PRIDE:P0CB22PRO:PR:P0CB22PROSITE:PS01359
PROSITE:PS50016PROSITE:PS50280PROSITE:PS50812PROSITE:PS50868
PROSITE:PS51542PROSITE:PS51543ProteinModelPortal:P0CB22Proteomes:UP000006548
RefSeq:NP_001077464.4RefSeq:NP_172074.6scanprosite:PS01359SMART:SM00249
SMART:SM00293SMART:SM00317SMART:SM00541SMART:SM00542
SMR:P0CB22STRING:3702.AT1G05830.1SUPFAM:SSF57903SUPFAM:SSF63748
SUPFAM:SSF82199TAIR:AT1G05830tair10-symbols:ATX2tair10-symbols:SDG30
UniGene:At.46306UniProt:P0CB22
Coordinates (TAIR10) chr1:+:1754452..1761225
Molecular Weight (calculated) 123293.00 Da
IEP (calculated) 7.93
GRAVY (calculated) -0.55
Length 1083 amino acids
Sequence (TAIR10)
(BLAST)
0001: MISMSCVPKE EEGEDTQIKT ELHDHAADNP VRYASLESVY SVSSSSSSLC CKTAAGSHKK VNALKLPMSD SFELQPHRRP EIVHVYCRRK RRRRRRRESF
0101: LELAILQNEG VERDDRIVKI ESAELDDEKE EENKKKKQKK RRIGNGELMK LGVDSTTLSV SATPPLRGCR IKAVCSGNKQ DGSSRSKRNT VKNQEKVVTA
0201: SATAKKWVRL SYDGVDPKHF IGLQCKVFWP LDAVWYPGSI VGYNVETKHH IVKYGDGDGE ELALRREKIK FLISRDDMEL LNMKFGTNDV VVDGQDYDEL
0301: VILAASFEEC QDFEPRDIIW AKLTGHAMWP AIIVDESVIV KRKGLNNKIS GGRSVLVQFF GTHDFARIQV KQAVSFLKGL LSRSPLKCKQ PRFEEAMEEA
0401: KMYLKEYKLP GRMDQLQKVA DTDCSERINS GEEDSSNSGD DYTKDGEVWL RPTELGDCLH RIGDLQIINL GRIVTDSEFF KDSKHTWPEG YTATRKFISL
0501: KDPNASAMYK MEVLRDAESK TRPVFRVTTN SGEQFKGDTP SACWNKIYNR IKKIQIASDN PDVLGEGLHE SGTDMFGFSN PEVDKLIQGL LQSRPPSKVS
0601: QRKYSSGKYQ DHPTGYRPVR VEWKDLDKCN VCHMDEEYEN NLFLQCDKCR MMVHTRCYGQ LEPHNGILWL CNLCRPVALD IPPRCCLCPV VGGAMKPTTD
0701: GRWAHLACAI WIPETCLLDV KKMEPIDGVK KVSKDRWKLL CSICGVSYGA CIQCSNNTCR VAYHPLCARA AGLCVELADE DRLFLLSMDD DEADQCIRLL
0801: SFCKRHRQTS NYHLETEYMI KPAHNIAEYL PPPNPSGCAR TEPYNYLGRR GRKEPEALAG ASSKRLFVEN QPYIVGGYSR HEFSTYERIY GSKMSQITTP
0901: SNILSMAEKY TFMKETYRKR LAFGKSGIHG FGIFAKLPHR AGDMVIEYTG ELVRPPIADK REHLIYNSMV GAGTYMFRID NERVIDATRT GSIAHLINHS
1001: CEPNCYSRVI SVNGDEHIII FAKRDVAKWE ELTYDYRFFS IDERLACYCG FPRCRGVVND TEAEERQANI HASRCELKEW TES
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)