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AT5G19220.1
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
plastid 1.000
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
  • PMID:31975158 (2020): plastid
  • PMID:31932409 (2020): plastid
  • PMID:31615849 (2019): plastid plastid thylakoid
  • PMID:31186290 (2019): plastid plastid stroma
  • PMID:30962257 (2019): plastid
  • PMID:30783145 (2019): extracellular region plant-type cell wall
  • PMID:30135097 (2018): plastid
  • PMID:29967049 (2018): plastid
  • PMID:28865150 (2017): extracellular region plant-type cell wall
  • PMID:27137770 (2016): plastid plastid stroma
  • PMID:25900983 (2015): Golgi trans-Golgi network
  • PMID:25900983 (2015): Golgi trans-Golgi network multivesicular body
  • PMID:24872594 (2014): plastid plastid stroma
  • PMID:24361574 (2014): plastid plastid stroma
  • PMID:24124904 (2013): plastid
  • PMID:23851315 (2013): plastid
  • PMID:23673981 (2013): plastid plastid stroma plastoglobules
  • PMID:21531424 (2011): plastid
  • PMID:20423899 (2010): plastid
  • PMID:20061580 (2010): plastid plastid stroma
  • PMID:18633119 (2008): plastid plastid stroma
  • PMID:18433418 (2008): plastid plastid thylakoid plastid thylakoid membrane
  • PMID:18431481 (2008): plastid plastid stroma
  • PMID:16207701 (2006): plastid
  • PMID:12938931 (2003): plastid
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : ADP glucose pyrophosphorylase large subunit 1
Curator
Summary (TAIR10)
Encodes the large subunit of ADP-glucose pyrophosphorylase which catalyzes the first, rate limiting step in starch biosynthesis. The large subunit plays a regulatory role whereas the small subunit (ApS) is the catalytic isoform. Four isoforms (ApL1-4) have been identified. ApL1 is the major large subunit isoform present in leaves. Mutational analysis of APS1 suggests that APL1 and APL2 can compensate for loss of APS1 catalytic activity,suggesting both have catalytic as well as regulatory functions.
Computational
Description (TAIR10)
ADP glucose pyrophosphorylase large subunit 1 (APL1); FUNCTIONS IN: glucose-1-phosphate adenylyltransferase activity; INVOLVED IN: cellulose biosynthetic process, biosynthetic process, glycogen biosynthetic process; LOCATED IN: chloroplast, chloroplast stroma, chloroplast envelope; EXPRESSED IN: 26 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Glucose-1-phosphate adenylyltransferase (InterPro:IPR011831), ADP-glucose pyrophosphorylase, conserved site (InterPro:IPR005836), Nucleotidyl transferase (InterPro:IPR005835); BEST Arabidopsis thaliana protein match is: ADPGLC-PPase large subunit (TAIR:AT1G27680.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).
Protein Annotations
BioCyc:ARA:AT5G19220-MONOMERBioCyc:MetaCyc:MONOMER-1823BioGrid:17318EC:2.7.7.27
eggNOG:COG0448eggNOG:ENOG410IMYMEMBL:AB022891EMBL:AC069326
EMBL:AF370503EMBL:BT008884EMBL:CP002688EMBL:U72290
EMBL:X73367EnsemblPlants:AT5G19220EnsemblPlants:AT5G19220.1entrez:832042
Gene3D:3.90.550.10GeneID:832042Genevisible:P55229GO:GO:0005524
GO:GO:0005978GO:GO:0008878GO:GO:0009507GO:GO:0009570
GO:GO:0009941GO:GO:0019252Gramene:AT5G19220.1gramene_plant_reactome:1119477
gramene_plant_reactome:6875956hmmpanther:PTHR22572hmmpanther:PTHR22572:SF119HOGENOM:HOG000278604
InParanoid:P55229InterPro:IPR005835InterPro:IPR005836InterPro:IPR011004
InterPro:IPR011831InterPro:IPR029044iPTMnet:P55229KEGG:00500+2.7.7.27
KEGG:00520+2.7.7.27KEGG:ath:AT5G19220KO:K00975OMA:GCFLDNC
PaxDb:P55229Pfam:P55229Pfam:PF00483PhylomeDB:P55229
PIR:S42548PIR:T52629PRIDE:P55229PRO:PR:P55229
PROSITE:PS00808PROSITE:PS00809PROSITE:PS00810ProteinModelPortal:P55229
Proteomes:UP000006548RefSeq:NP_197423.1SABIO-RK:P55229scanprosite:PS00808
scanprosite:PS00809scanprosite:PS00810SMR:P55229STRING:3702.AT5G19220.1
SUPFAM:SSF51161SUPFAM:SSF53448TAIR:AT5G19220tair10-symbols:ADG2
tair10-symbols:APL1TIGRfam:TIGR02091TIGRFAMs:TIGR02091UniGene:At.31320
UniGene:At.429UniGene:At.69509UniPathway:UPA00152unipathway:UPA00164
UniProt:P55229
Coordinates (TAIR10) chr5:-:6463931..6466775
Molecular Weight (calculated) 57677.10 Da
IEP (calculated) 8.04
GRAVY (calculated) -0.17
Length 522 amino acids
Sequence (TAIR10)
(BLAST)
001: MVVSADCRIS LSAPSCIRSS STGLTRHIKL GSFCNGELMG KKLNLSQLPN IRLRSSTNFS QKRILMSLNS VAGESKVQEL ETEKRDPRTV ASIILGGGAG
101: TRLFPLTKRR AKPAVPIGGA YRLIDVPMSN CINSGINKVY ILTQYNSASL NRHLARAYNS NGLGFGDGYV EVLAATQTPG ESGKRWFQGT ADAVRQFHWL
201: FEDARSKDIE DVLILSGDHL YRMDYMDFIQ DHRQSGADIS ISCIPIDDRR ASDFGLMKID DKGRVISFSE KPKGDDLKAM AVDTTILGLS KEEAEKKPYI
301: ASMGVYVFKK EILLNLLRWR FPTANDFGSE IIPFSAKEFY VNAYLFNDYW EDIGTIRSFF EANLALTEHP GAFSFYDAAK PIYTSRRNLP PSKIDNSKLI
401: DSIISHGSFL TNCLIEHSIV GIRSRVGSNV QLKDTVMLGA DYYETEAEVA ALLAEGNVPI GIGENTKIQE CIIDKNARVG KNVIIANSEG IQEADRSSDG
501: FYIRSGITVI LKNSVIKDGV VI
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)