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AT2G40840.1
Subcellular Consensus
(Prediction and Experimental)

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SUBAcon:
cytosol 1.000
ASURE: cytosol
What is SUBAcon?
What is ASURE?
SUBAcon computations
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : disproportionating enzyme 2
Curator
Summary (TAIR10)
Encodes a cytosolic protein with transglucosidase and amylomaltase activity. It is an essential component of the pathway from starch to sucrose and cellular metabolism in leaves at night. The protein binds to heteroglycans and utilizes glucose, mannose and xylose as acceptors. Fucose and galactose can also act as acceptors but less efficiently than the previous three. It was also was also recently reported to act on maltodextrins. On the other hand, arabinose and fructose were not efficiently used. Its role probably includes metabolizing maltose exported from the chloroplast. Studies using maltose extracted from the double mutant be2-1 be3-2 showed that this enzyme is preferentially active of β-maltose.
Computational
Description (TAIR10)
disproportionating enzyme 2 (DPE2); FUNCTIONS IN: 4-alpha-glucanotransferase activity, heteroglycan binding; INVOLVED IN: polysaccharide metabolic process, circadian rhythm, maltose catabolic process, maltose metabolic process, starch catabolic process; LOCATED IN: cytosol; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Immunoglobulin-like fold (InterPro:IPR013783), Carbohydrate-binding-like fold (InterPro:IPR013784), Glycoside hydrolase, family 77 (InterPro:IPR003385), Glycoside hydrolase, catalytic core (InterPro:IPR017853), Glycoside hydrolase, carbohydrate-binding (InterPro:IPR002044), Glycoside hydrolase, subgroup, catalytic core (InterPro:IPR013781); BEST Arabidopsis thaliana protein match is: disproportionating enzyme (TAIR:AT5G64860.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).
Protein Annotations
BioCyc:ARA:AT2G40840-MONOMERBioGrid:4019BRENDA:2.4.1.25CAZy:CBM20CAZy:GH77EC:2.4.1.25eggNOG:COG1640
eggNOG:ENOG410IE02EMBL:AC002409EMBL:AY081315EMBL:BT010364EMBL:CP002685EnsemblPlants:AT2G40840EnsemblPlants:AT2G40840.1
entrez:818682Gene3D:2.60.40.10Gene3D:3.20.20.80GeneID:818682Genevisible:Q8RXD9GO:GO:0000023GO:GO:0000025
GO:GO:0004134GO:GO:0005829GO:GO:0005976GO:GO:0005977GO:GO:0005983GO:GO:0010297GO:GO:2001070
Gramene:AT2G40840.1gramene_pathway:2.4.1.25gramene_pathway:PWY-842hmmpanther:PTHR32518hmmpanther:PTHR32518:SF3HOGENOM:HOG000291097InParanoid:Q8RXD9
InterPro:IPR002044InterPro:IPR003385InterPro:IPR013781InterPro:IPR013783InterPro:IPR013784InterPro:IPR017853iPTMnet:Q8RXD9
KEGG:00500+2.4.1.25KEGG:ath:AT2G40840KO:K00705OMA:FHYYIQYPaxDb:Q8RXD9Pfam:PF00686Pfam:PF02446
Pfam:Q8RXD9Pfscan:PS51166PhylomeDB:Q8RXD9PIR:T00748PRIDE:Q8RXD9PRO:PR:Q8RXD9PROSITE:PS51166
ProteinModelPortal:Q8RXD9Proteomes:UP000006548RefSeq:NP_181616.3SMART:SM01065SMR:Q8RXD9STRING:3702.AT2G40840.1SUPFAM:SSF49452
SUPFAM:SSF51445TAIR:AT2G40840tair10-symbols:DPE2UniGene:At.44028UniProt:Q8RXD9
Coordinates (TAIR10) chr2:+:17045368..17050779
Molecular Weight (calculated) 109782.00 Da
IEP (calculated) 5.59
GRAVY (calculated) -0.43
Length 955 amino acids
Sequence (TAIR10)
(BLAST)
001: MMNLGSLSLS TSKSSKPMVS ISFWIPYFTH WGESLLVCGS APGLGSGNVK KGLLLKPSQQ DDQLIWSGSV SVPPGFSSDY CYYVVDDSKS VLRSEFGMKR
101: KLVVPETLTG GESVHLRDLW QSGDQALPFR SAFKDVIFHH SFDVKVEKPL GVFMNKSDQD DSVVVQFKIC CPDIGEGTSV YVLGTPEKLG NWKVENGLRL
201: NYVDDSIWEA DCLIPKADFP IKYRYCKVQK EDSIGFESGG NRELSLHSIG SKQEYIVMSD GLFRAMPWRG AGVAVPMFSV RSEDDVGVGE FLDLKLLVDW
301: AVDSGLHLVQ LLPVNDTSVH KMWWDSYPYS SLSVFALHPL YLRVQALSER LPEDIKEEIQ KAKNQLDKND VDYEATMETK LSIAKKIFDI EKDQTLNSST
401: FQKFFSENEG WLKPYAAFCF LRDFFETSDH SQWGTFSDYT DDKLEKLISK DNLHYNTICF HYYIQYHLHV QLSAAAEYAR KKGVVLKGDL PIGVDRNSVD
501: TWVYRNLFRM NTSTGAPPDY FDKNGQNWGF PTYNWEEMSK DNYAWWRARL TQMGKYFTAY RIDHILGFFR IWELPAHAMT GLVGKFRPSI PLSQEELEKE
601: GIWDFDRLSK PYIQKKFLEE KFGDFWPFIA SNFLNETQKD MYEFKEDCNT EKKIVAKLKS LAEKSLLLEN EDKVRRDVFD ILRNVVLIKD PEDARKFYPR
701: FNIEDTSSFQ DLDDHSKNVL KRLYYDYYFQ RQEDLWRKNA LKTLPALLNS SNMLACGEDL GLIPSCVHPV MQELGLVGLR IQRMPSESDV KFGIPSNYDY
801: MTVCAPSCHD CSTLRAWWEE DEERRQQYFK EVIGVDGIPP SQCIPEITHF ILRQHVEAPS MWAIFPLQDM MALKEEYTTR PATEETINDP TNPKHYWRYR
901: VHVTLDSLLK DTDLKSTIKN LVSSSGRSVP ANVSGEDINK SRGEVIANGS TKPNP
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)