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AT2G07050.1
Subcellular Consensus
(Prediction and Experimental)

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SUBAcon:
golgi 0.994
What is SUBAcon?
What is ASURE?
SUBAcon computations
Experimental Localisations and PPI
FP MS/MS PPI
  • PMID:27943495 (2017): mitochondrion
  • PMID:25900983 (2015): Golgi
  • PMID:25900983 (2015): plant-type vacuole plant-type vacuole membrane
  • PMID:25900983 (2015): Golgi trans-Golgi network multivesicular body
  • PMID:25900983 (2015): Golgi trans-Golgi network early endosome
  • PMID:25900983 (2015): Golgi trans-Golgi network
  • PMID:25900983 (2015): Golgi Golgi apparatus Golgi membrane
  • PMID:23903016 (2013): plant-type vacuole plant-type vacuole membrane
  • PMID:22215637 (2012): plasma membrane
  • PMID:21433285 (2011): plasma membrane
  • PMID:19334764 (2009): plasma membrane
  • PMID:15539469 (2004): plant-type vacuole
  • PMID:15215502 (2004): plant-type vacuole
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : cycloartenol synthase 1
Curator
Summary (TAIR10)
Involved in the biosynthesis of brassinosteroids. Catalyzes the reaction from epoxysqualene to cycloartenol.
Computational
Description (TAIR10)
cycloartenol synthase 1 (CAS1); FUNCTIONS IN: cycloartenol synthase activity; INVOLVED IN: pentacyclic triterpenoid biosynthetic process, thylakoid membrane organization, pollen development; LOCATED IN: vacuole; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Terpene synthase, conserved site (InterPro:IPR002365), Terpenoid cylases/protein prenyltransferase alpha-alpha toroid (InterPro:IPR008930), Squalene cyclase (InterPro:IPR018333), Prenyltransferase/squalene oxidase (InterPro:IPR001330); BEST Arabidopsis thaliana protein match is: lanosterol synthase 1 (TAIR:AT3G45130.1); Has 2063 Blast hits to 1929 proteins in 563 species: Archae - 2; Bacteria - 902; Metazoa - 86; Fungi - 243; Plants - 616; Viruses - 0; Other Eukaryotes - 214 (source: NCBI BLink).
Protein Annotations
BindingDB:P38605BioCyc:ARA:AT2G07050-MONOMERBioCyc:MetaCyc:AT2G07050-MONOMERBRENDA:5.4.99.8ChEMBL:CHEMBL5356EC:5.4.99.8eggNOG:COG1657
eggNOG:KOG0497EMBL:AC005171EMBL:AY094394EMBL:BT001118EMBL:CP002685EMBL:U02555EnsemblPlants:AT2G07050
EnsemblPlants:AT2G07050.1entrez:815275Gene3D:1.50.10.20GeneID:815275Genevisible:P38605GO:GO:0005773GO:GO:0009555
GO:GO:0010027GO:GO:0016871GO:GO:0019745Gramene:AT2G07050.1gramene_pathway:5.4.99.-gramene_pathway:5.4.99.8gramene_pathway:PWY-112
gramene_pathway:PWY-2541gramene_pathway:PWY-5377gramene_pathway:PWY-6663hmmpanther:PTHR11764hmmpanther:PTHR11764:SF15HOGENOM:HOG000234317InParanoid:P38605
InterPro:IPR002365InterPro:IPR008930InterPro:IPR018333InterPro:IPR032696InterPro:IPR032697KEGG:ath:AT2G07050KO:K01853
ncoils:CoilOMA:SQWYRHIPaxDb:P38605Pfam:P38605Pfam:PF13243Pfam:PF13249PhylomeDB:P38605
PIR:A49398PIR:H84481PRIDE:P38605PRO:PR:P38605PROSITE:PS01074ProteinModelPortal:P38605Proteomes:UP000006548
Reactome:R-ATH-191273RefSeq:NP_178722.1scanprosite:PS01074SMR:P38605STRING:3702.AT2G07050.1SUPFAM:SSF48239TAIR:AT2G07050
tair10-symbols:CAS1TIGRfam:TIGR01787TIGRFAMs:TIGR01787UniGene:At.10550UniProt:P38605
Coordinates (TAIR10) chr2:+:2924629..2930295
Molecular Weight (calculated) 86037.90 Da
IEP (calculated) 6.01
GRAVY (calculated) -0.24
Length 759 amino acids
Sequence (TAIR10)
(BLAST)
001: MWKLKIAEGG SPWLRTTNNH VGRQFWEFDP NLGTPEDLAA VEEARKSFSD NRFVQKHSAD LLMRLQFSRE NLISPVLPQV KIEDTDDVTE EMVETTLKRG
101: LDFYSTIQAH DGHWPGDYGG PMFLLPGLII TLSITGALNT VLSEQHKQEM RRYLYNHQNE DGGWGLHIEG PSTMFGSVLN YVTLRLLGEG PNDGDGDMEK
201: GRDWILNHGG ATNITSWGKM WLSVLGAFEW SGNNPLPPEI WLLPYFLPIH PGRMWCHCRM VYLPMSYLYG KRFVGPITST VLSLRKELFT VPYHEVNWNE
301: ARNLCAKEDL YYPHPLVQDI LWASLHKIVE PVLMRWPGAN LREKAIRTAI EHIHYEDENT RYICIGPVNK VLNMLCCWVE DPNSEAFKLH LPRIHDFLWL
401: AEDGMKMQGY NGSQLWDTGF AIQAILATNL VEEYGPVLEK AHSFVKNSQV LEDCPGDLNY WYRHISKGAW PFSTADHGWP ISDCTAEGLK AALLLSKVPK
501: AIVGEPIDAK RLYEAVNVII SLQNADGGLA TYELTRSYPW LELINPAETF GDIVIDYPYV ECTSAAIQAL ISFRKLYPGH RKKEVDECIE KAVKFIESIQ
601: AADGSWYGSW AVCFTYGTWF GVKGLVAVGK TLKNSPHVAK ACEFLLSKQQ PSGGWGESYL SCQDKVYSNL DGNRSHVVNT AWAMLALIGA GQAEVDRKPL
701: HRAARYLINA QMENGDFPQQ EIMGVFNRNC MITYAAYRNI FPIWALGEYR CQVLLQQGE
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)