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AT1G74260.1
Subcellular Consensus
(Prediction and Experimental)

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SUBAcon:
plastid 0.500
mitochondrion 0.500
ASURE: mitochondrion,plastid
What is SUBAcon?
What is ASURE?
SUBAcon computations
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : purine biosynthesis 4
Curator
Summary (TAIR10)
Encodes formylglycinamidine ribonucleotide synthase an enzyme involved in de novo purine biosynthesis. PUR4 is localizes to the chloroplast and mitochondria. Loss of PUR4 function affects male but not female gametophyte development.
Computational
Description (TAIR10)
purine biosynthesis 4 (PUR4); FUNCTIONS IN: phosphoribosylformylglycinamidine synthase activity, catalytic activity, ATP binding; INVOLVED IN: microgametogenesis, pollen development; LOCATED IN: mitochondrion, chloroplast stroma, chloroplast; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: PurM, N-terminal-like (InterPro:IPR016188), Phosphoribosylformylglycinamidine synthase, eukaryote/proteobacteria (InterPro:IPR010073), AIR synthase related protein (InterPro:IPR000728), AIR synthase related protein, C-terminal (InterPro:IPR010918), Glutamine amidotransferase type 1 (InterPro:IPR017926); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).
Protein Annotations
BioCyc:ARA:AT1G74260-MONOMEREC:6.3.5.3eggNOG:COG0046eggNOG:COG0047eggNOG:ENOG410JUJJeggNOG:KOG1907EMBL:AC020579
EMBL:CP002684EMBL:EU091297EnsemblPlants:AT1G74260EnsemblPlants:AT1G74260.1entrez:843766Gene3D:3.30.1330.10Gene3D:3.40.50.880
GeneID:843766Genevisible:Q9M8D3GO:GO:0004642GO:GO:0005524GO:GO:0005739GO:GO:0006189GO:GO:0006541
GO:GO:0009507GO:GO:0046872Gramene:AT1G74260.1gramene_pathway:6.3.5.3gramene_pathway:PWY-6121HAMAP:MF_00419hmmpanther:PTHR10099
hmmpanther:PTHR10099:SF1HOGENOM:HOG000261358InParanoid:Q9M8D3InterPro:IPR010073InterPro:IPR010918InterPro:IPR016188InterPro:IPR017926
InterPro:IPR029062KEGG:00230+6.3.5.3KEGG:ath:AT1G74260KO:K01952OMA:LSANWMWPaxDb:Q9M8D3Pfam:PF02769
Pfam:PF13507Pfam:Q9M8D3Pfscan:PS51273PIR:A96771PRIDE:Q9M8D3PRO:PR:Q9M8D3PROSITE:PS51273
ProteinModelPortal:Q9M8D3Proteomes:UP000006548Reactome:R-ATH-73817RefSeq:NP_177566.3SMR:Q9M8D3STRING:3702.AT1G74260.1SUPFAM:0049526
SUPFAM:SSF52317SUPFAM:SSF55326SUPFAM:SSF56042SUPFAM:SSF82697TAIR:AT1G74260tair10-symbols:PUR4TIGRfam:TIGR01735
TIGRFAMs:TIGR01735UniGene:At.34898UniPathway:UPA00074UniProt:Q9M8D3
Coordinates (TAIR10) chr1:-:27923005..27927764
Molecular Weight (calculated) 153962.00 Da
IEP (calculated) 5.00
GRAVY (calculated) -0.14
Length 1407 amino acids
Sequence (TAIR10)
(BLAST)
0001: MNTSQATRAA LFLNGSNRQA MLLQRSSMSQ LWGSVRMRTS RLSLNRTKAV SLRCSAQPNK PKAAVSTGSF VTADELPSLV EKPAAEVIHF YRVPLIQESA
0101: NAELLKAVQT KISNQIVSLT TEQSFNIGLE SKLKDEKLSV LKWILQETYE PENLGTDSFL ERKKQEGLHA VIVEVGPRLS FTTAWSTNAV SICRACGLDE
0201: VTRLERSRRY LLFSKEPLLE NQIKEFAAMV HDRMTECVYT QKLVSFETNV VPEEVKYVPV MEKGRKALEE INQEMGLAFD EQDLQYYTRL FREDIKRDPT
0301: NVELFDIAQS NSEHSRHWFF AGNMVIDGKP MDKSLMQIVK STWEANRNNS VIGFKDNSSA IRGFLVNQLR PLLPGSVCLL DVSARDLDIL FTAETHNFPC
0401: AVAPYPGAET GAGGRIRDTH ATGRGSFVVA STSGYCVGNL NMEGSYAPWE DSSFQYPSNL ASPLQILIDA SNGASDYGNK FGEPMIQGYT RTFGMRLPSG
0501: DRREWLKPIM FSAGIGQIDH THITKGEPEV GMLVVKIGGP AYRIGMGGGA ASSMVSGQND AELDFNAVQR GDAEMSQKLY RVVRACIEMG EKNPIISIHD
0601: QGAGGNCNVV KEIIYPQGAE IDIRAVVVGD HTMSVLEIWG AEYQEQDAIL VKAESREILQ SICKRERLSM AVIGTINGGG RCTLIDSTAA AKCSKEGLPP
0701: PPPAVDLELE KVLGDMPKKT FKFNRIAYAR EPLDIAPGIT LMDALKRVLR LPSVSSKRFL TTKVDRCVTG LVAQQQTVGP LQITLADVAV IAQTFTDLTG
0801: GACAIGEQPI KGLLDPKAMA RLAVGEALTN LVWAKVTALS DVKASGNWMY AAKLEGEGSA MYDAAIALSE AMIELGIAID GGKDSLSMAA HADGEVVKAP
0901: GNLVISAYVT CPDITKTVTP DLKLGGDDGI LLHVDLAKGK RRLGGSALAQ VFGQIGNDCP DLDDVPYLKN VFDGVQALIA ENLVSAGHDI SDGGLVVTAL
1001: EMAFAGNKGI NLDLASNGIS LFETLFSEEL GLVLEISKTN LDAVMEKLRA FDVTAEIIGN VTDSPLIEVK VDGITHLSEK TSFLRDMWED TSFQLEKLQR
1101: LASCVEMEKE GLKFRHEPNW KLSFIPSSTN NNYMSQDVKP KVAVIREEGS NGDREMSAAF YAAGFEPWDV TVSDLLAGDI TLDQFRGIVF VGGFSYADVL
1201: DSAKGWAASI RFNEPVLSQF QEFYKRPDTF SLGICNGCQL MALLGWVPGP QVGGSLDTSQ PRFVHNESGR FECRFTSVTI KDSPSIMLKG MEGSTLGVWA
1301: AHGEGRAYFP DEGVLDHMLH SDLAPLRYCD DDGNVTEAYP FNLNGSPLGI AAICSPDGRH LAMMPHPERC FLMWQFPWYP TSWDVEKAGP SPWLKMFQNA
1401: RDWLESC
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)