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AT1G31230.1
Subcellular Consensus
(Prediction and Experimental)

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SUBAcon:
plastid 1.000
What is SUBAcon?
What is ASURE?
SUBAcon computations
Experimental Localisations and PPI
FP MS/MS PPI
  • PMID:24361574 (2014): plastid plastid stroma
  • PMID:23549413 (2013): plastid plastid stroma
  • PMID:21531424 (2011): plastid
  • PMID:20423899 (2010): plastid
  • PMID:20061580 (2010): plastid plastid stroma
  • PMID:18633119 (2008): plastid plastid stroma
  • PMID:18431481 (2008): plastid plastid stroma
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : aspartate kinase-homoserine dehydrogenase i
Curator
Summary (TAIR10)
Encodes a bifunctional aspartate kinase/homoserine dehydrogenase. These two activities catalyze the first and the third steps toward the synthesis of the essential amino acids threonine, isoleucine and methionine.
Computational
Description (TAIR10)
aspartate kinase-homoserine dehydrogenase i (AK-HSDH I); FUNCTIONS IN: homoserine dehydrogenase activity, aspartate kinase activity; INVOLVED IN: aspartate family amino acid biosynthetic process; LOCATED IN: chloroplast stroma, chloroplast; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Aspartate/glutamate/uridylate kinase (InterPro:IPR001048), Homoserine dehydrogenase, catalytic (InterPro:IPR001342), Amino acid-binding ACT (InterPro:IPR002912), Aspartate/homoserine dehydrogenase, NAD-binding (InterPro:IPR005106), Aspartate kinase, conserved site (InterPro:IPR018042), Bifunctional aspartokinase/homoserine dehydrogenase I (InterPro:IPR011147), NAD(P)-binding domain (InterPro:IPR016040), Aspartate kinase domain (InterPro:IPR001341), Homoserine dehydrogenase, conserved site (InterPro:IPR019811); BEST Arabidopsis thaliana protein match is: aspartate kinase-homoserine dehydrogenase ii (TAIR:AT4G19710.2); Has 17266 Blast hits to 16993 proteins in 2572 species: Archae - 397; Bacteria - 11403; Metazoa - 7; Fungi - 300; Plants - 257; Viruses - 0; Other Eukaryotes - 4902 (source: NCBI BLink).
Protein Annotations
BioGrid:25246EC:1.1.1.3EC:2.7.2.4eggNOG:COG0460eggNOG:COG0527eggNOG:ENOG410IFE2EMBL:AC004793
EMBL:AC007654EMBL:AK118779EMBL:CP002684EMBL:X71364EnsemblPlants:AT1G31230EnsemblPlants:AT1G31230.1entrez:840011
Gene3D:3.40.1160.10Gene3D:3.40.50.720GeneID:840011Genevisible:Q9SA18GO:GO:0004072GO:GO:0004412GO:GO:0005524
GO:GO:0009086GO:GO:0009088GO:GO:0009089GO:GO:0009507GO:GO:0009570GO:GO:0016597GO:GO:0050661
Gramene:AT1G31230.1gramene_pathway:1.1.1.3gramene_pathway:2.7.2.4gramene_pathway:HOMOSERSYN-PWYgramene_pathway:PWY-5097hmmpanther:PTHR21499hmmpanther:PTHR21499:SF30
HOGENOM:HOG000271593InParanoid:Q9SA18IntAct:Q9SA18InterPro:IPR001048InterPro:IPR001341InterPro:IPR001342InterPro:IPR002912
InterPro:IPR005106InterPro:IPR016040InterPro:IPR018042InterPro:IPR019811InterPro:IPR027795iPTMnet:Q9SA18KEGG:00260+1.1.1.3
KEGG:00260+2.7.2.4KEGG:00261+2.7.2.4KEGG:00270+1.1.1.3KEGG:00270+2.7.2.4KEGG:00300+1.1.1.3KEGG:00300+2.7.2.4KEGG:ath:AT1G31230
KO:K12524MINT:MINT-8067838ncoils:CoilOMA:RYYSPIPPaxDb:Q9SA18Pfam:PF00696Pfam:PF00742
Pfam:PF01842Pfam:PF03447Pfam:PF13840Pfam:Q9SA18Pfscan:PS51671PhylomeDB:Q9SA18PIR:E86438
PIR:S46497PRIDE:Q9SA18PRO:PR:Q9SA18PROSITE:PS00324PROSITE:PS01042PROSITE:PS51671ProteinModelPortal:Q9SA18
Proteomes:UP000006548RefSeq:NP_174408.1SABIO-RK:Q9SA18scanprosite:PS00324scanprosite:PS01042SMR:Q9SA18STRING:3702.AT1G31230.1
SUPFAM:SSF51735SUPFAM:SSF53633SUPFAM:SSF55021SUPFAM:SSF55347TAIR:AT1G31230tair10-symbols:AK-HSDHtair10-symbols:AK-HSDH I
TIGRfam:TIGR00657TIGRFAMs:TIGR00657UniGene:At.48251UniGene:At.71214UniPathway:UPA00034UniPathway:UPA00050UniPathway:UPA00051
UniProt:Q9SA18
Coordinates (TAIR10) chr1:-:11158744..11163055
Molecular Weight (calculated) 99409.60 Da
IEP (calculated) 6.75
GRAVY (calculated) -0.02
Length 911 amino acids
Sequence (TAIR10)
(BLAST)
001: MPVVSLAKVV TSPAVAGDLA VRVPFIYGKR LVSNRVSFGK LRRRSCIGQC VRSELQSPRV LGSVTDLALD NSVENGHLPK GDSWAVHKFG GTCVGNSERI
101: KDVAAVVVKD DSERKLVVVS AMSKVTDMMY DLIHRAESRD DSYLSALSGV LEKHRATAVD LLDGDELSSF LARLNDDINN LKAMLRAIYI AGHATESFSD
201: FVVGHGELWS AQMLAAVVRK SGLDCTWMDA RDVLVVIPTS SNQVDPDFVE SEKRLEKWFT QNSAKIIIAT GFIASTPQNI PTTLKRDGSD FSAAIMSALF
301: RSHQLTIWTD VDGVYSADPR KVSEAVVLKT LSYQEAWEMS YFGANVLHPR TIIPVMKYDI PIVIRNIFNL SAPGTMICRQ IDDEDGFKLD APVKGFATID
401: NLALVNVEGT GMAGVPGTAS AIFSAVKEVG ANVIMISQAS SEHSVCFAVP EKEVKAVSEA LNSRFRQALA GGRLSQIEII PNCSILAAVG QKMASTPGVS
501: ATFFNALAKA NINIRAIAQG CSEFNITVVV KREDCIRALR AVHSRFYLSR TTLAVGIIGP GLIGGTLLDQ IRDQAAVLKE EFKIDLRVIG ITGSSKMLMS
601: ESGIDLSRWR ELMKEEGEKA DMEKFTQYVK GNHFIPNSVM VDCTADADIA SCYYDWLLRG IHVVTPNKKA NSGPLDQYLK IRDLQRKSYT HYFYEATVGA
701: GLPIISTLRG LLETGDKILR IEGIFSGTLS YLFNNFVGTR SFSEVVAEAK QAGFTEPDPR DDLSGTDVAR KVTILARESG LKLDLEGLPV QNLVPKPLQA
801: CASAEEFMEK LPQFDEELSK QREEAEAAGE VLRYVGVVDA VEKKGTVELK RYKKDHPFAQ LSGADNIIAF TTKRYKEQPL IVRGPGAGAQ VTAGGIFSDI
901: LRLAFYLGAP S
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)